Zobrazeno 1 - 10
of 192
pro vyhledávání: '"Ruth, Dobson"'
Autor:
Benjamin M. Jacobs, Daniel Stow, Sam Hodgson, Julia Zöllner, Miriam Samuel, Stavroula Kanoni, Saeed Bidi, Genes & Health Research Team, Klaudia Walter, Claudia Langenberg, Ruth Dobson, Sarah Finer, Caroline Morton, Moneeza K. Siddiqui, Hilary C. Martin, Maik Pietzner, Rohini Mathur, David A. van Heel
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Understanding the genetic basis of routinely-acquired blood tests can provide insights into several aspects of human physiology. We report a genome-wide association study of 42 quantitative blood test traits defined using Electronic Healthca
Externí odkaz:
https://doaj.org/article/a55af57d72a54cd593f54dfaf2d077e0
Autor:
Ashvin Kuri, David E. Henshall, Daoud Chaudhry, Setthasorn Zhi Yang Ooi, Qiqi Zhang, Joela Mathews, Alison Thomson, David Rog, Jeremy Hobart, Ruth Dobson, Neurology and Neurosurgery Interest Group (NANSIG)
Publikováno v:
BMC Neurology, Vol 24, Iss 1, Pp 1-10 (2024)
Abstract Background Multiple sclerosis (MS) is a leading cause of non-traumatic disability in young adults. Accumulating evidence indicates early diagnosis and early treatment improves long-term outcomes. However, the MS diagnostic pathway is increas
Externí odkaz:
https://doaj.org/article/18b9a36e6c7f4a628043f1afbd140a9d
Autor:
Benjamin M. Jacobs, Nicola Vickaryous, Gavin Giovannoni, Petroula Proitsi, Sheena Waters, Ruth Dobson
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 11, Iss 3, Pp 698-709 (2024)
Abstract Objective We aimed to describe plasma protein biomarkers of multiple sclerosis risk and to explore protein biomarkers of disease severity using radiological outcome measures. Methods Multiple sclerosis cases and controls were identified in U
Externí odkaz:
https://doaj.org/article/38f9e8643b704256bf2707678525dd96
Autor:
Ruth Dobson, Alastair Noyce, Peter MacCallum, Veronica White, Thomas H Massey, Joseph Walton, Devan Mair, Safiya A Zaloum, Marta Patyjewicz, Barbara Onen, Christine Joerres, Apeksha Madhusudan Shah, Tadbir Bariana, Sarah A De Freitas
Publikováno v:
BMJ Neurology Open, Vol 6, Iss 1 (2024)
Background The study aimed to elucidate the prevalence of nitrous oxide (N2O) usage in patients with unexplained venous thromboembolism (VTE), highlighting the potential association with hyperhomocysteinaemia (HHcy).Methods We conducted a retrospecti
Externí odkaz:
https://doaj.org/article/528e6af9dce04ec68eec82f2a4a6f460
Autor:
Benjamin M. Jacobs, Cyrus Daruwalla, Mollie O. McKeon, Raghda Al-Najjar, Andrea Simcock-Davies, Katherine Tuite-Dalton, J. William L. Brown, Ruth Dobson, Jeff Rodgers, Rod Middleton
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-6 (2023)
Abstract Understanding the associations and potential drivers of long-term disability in Multiple Sclerosis (MS) is of clinical and prognostic value. Previous data have suggested a link between depression and disability accrual in MS. We aimed to det
Externí odkaz:
https://doaj.org/article/d72350bc2bba4056a62e8cab9c02ceb1
Autor:
Panagiotis Gklinos, Ruth Dobson
Publikováno v:
Antibodies, Vol 13, Iss 2, p 43 (2024)
Clinical syndromes associated with antibodies against myelin oligodendrocyte glycoprotein (MOG) are now recognized as a distinct neurological disease entity, and are gaining increasing attention. The pathogenic mechanisms underlying MOG-antibody dise
Externí odkaz:
https://doaj.org/article/984b55a1af1f4c658726aaa8dc80b6f6
Publikováno v:
Advances in Clinical Neuroscience & Rehabilitation, Vol , Iss (2023)
As the UK population ages, dementia affects an increasing proportion of the population. There is a drive to accelerate dementia research, however access to research is not equitably distributed. We examine access to dementia research and discuss some
Externí odkaz:
https://doaj.org/article/6e63f67f8e7b4cf48efc6311a17e49a4
Publikováno v:
EClinicalMedicine, Vol 63, Iss , Pp 102157- (2023)
Summary: A range of long-term neurological conditions may be diagnosed in young adulthood. These conditions are generally not curable, and most people need to take ongoing treatment for symptom control and/or disease modification. When chronic diseas
Externí odkaz:
https://doaj.org/article/f415fbcdda9646079843c1911eb33fbd
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-6 (2022)
Abstract Multiple Sclerosis (MS) has been linked to a variety of environmental risk factors, including smoking, Epstein-Barr Virus infection, and childhood obesity. There is some evidence to support a relationship between alcohol consumption and MS r
Externí odkaz:
https://doaj.org/article/efb32f91e1bd4005a50d6499de323b46
Autor:
Gavin Giovannoni, Eli Silber, Ruth Dobson, Riffat Tanveer, Jade Harris, Tarunya Arun, Miriam Mattoscio, Ghaniah Hassan-Smith, Huw Morris, Rod Middleton, Emma Tallantyre, David Rog, Nikos Evangelou, Benjamin M Jacobs, Antonio Scalfari, Waqar Rashid, Helen L Ford, Charles A Mein, Stephen Sawcer, Cord Spilker, Bruno Gran, Martin O'Malley, Ashwini Nandoskar, Emeka Uzochukwu, Katila George, Sadid Hoque, Luisa Schalk, Angie Dunne, Charlotte Sellers, Elisa Visentin, Elizabeth Lindsey Bezzina, Eva Wozniak, Eve Sacre, Joan Bradley, Joshua Breedon, Judith Brooke, Karim L Kreft, Katherine Tuite Dalton, Maria Papachatzaki, Michelle Peter, Neisha Rhule, Nimisha Vinod, Outi Quinn, Ramya Shamji, Rashmi Kaimal, Rebecca Boulton, Roxanne Murray, Ruth Bellfield, Shakeelah Patel, Sonia Raj, Stephanie Gumus, Stephanie Mitchell, Tatiana Pogreban, Terri-Louise Brown, Thamanna Begum, Veronica Antoine
Publikováno v:
BMJ Open, Vol 13, Iss 5 (2023)
Purpose Genetic studies of multiple sclerosis (MS) susceptibility and severity have focused on populations of European ancestry. Studying MS genetics in other ancestral groups is necessary to determine the generalisability of these findings. The gene
Externí odkaz:
https://doaj.org/article/dfaa829aa3244981a9b0642497517dd8