Výsledky vyhledávání - "Rutger van der Schrier"

Akademický článek

A biomarker of opioid-induced respiratory toxicity in experimental studies

Autor: Marieke Hellinga, Marijke Hyke Algera, Rutger van der Schrier, Elise Sarton, Monique van Velzen, Albert Dahan, Erik Olofsen, Marieke Niesters

Publikováno v: iScience, Vol 26, Iss 4, Pp 106520- (2023)

Summary: Opioids are commonly used painkillers and drugs of abuse and have serious toxic effects including potentially lethal respiratory depression. It remains unknown which respiratory parameter is the most sensitive biomarker of opioid-induced res

Externí odkaz: https://doaj.org/article/63648f48afb7473eb08b1c02f75d6390

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Akademický článek

Carbon dioxide tolerability and toxicity in rat and man: A translational study

Autor: Rutger van der Schrier, Monique van Velzen, Margot Roozekrans, Elise Sarton, Erik Olofsen, Marieke Niesters, Chantal Smulders, Albert Dahan

Publikováno v: Frontiers in Toxicology, Vol 4 (2022)

Background: Due the increasing need for storage of carbon dioxide (CO2) more individuals are prone to be exposed to high concentrations of CO2 accidentally released into atmosphere, with deleterious consequences.Methods: We tested the effect of incre

Externí odkaz: https://doaj.org/article/2bfe9546b0df4bbe8d5892b79c1cbc70

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Akademický článek

S-Ketamine oral thin film—Part 2: Population pharmacodynamics of S-ketamine, S-norketamine and S-hydroxynorketamine

Autor: Pieter Simons, Erik Olofsen, Monique van Velzen, Maarten van Lemmen, Tom van Dasselaar, Patrick Mohr, Florian Hammes, Rutger van der Schrier, Marieke Niesters, Albert Dahan

Publikováno v: Frontiers in Pain Research, Vol 3 (2022)

Ketamine is a versatile drug used for many indications and is administered via various routes. Here, we report on the pharmacodynamics of sublingual and buccal fast-dissolving oral-thin-films that contain 50 mg of S-ketamine in a population of health

Externí odkaz: https://doaj.org/article/117bbb0187bd4f1b8f7a7cbaff33e83d

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Akademický článek

S-Ketamine Oral Thin Film—Part 1: Population Pharmacokinetics of S-Ketamine, S-Norketamine and S-Hydroxynorketamine

Autor: Pieter Simons, Erik Olofsen, Monique van Velzen, Maarten van Lemmen, René Mooren, Tom van Dasselaar, Patrick Mohr, Florian Hammes, Rutger van der Schrier, Marieke Niesters, Albert Dahan

Publikováno v: Frontiers in Pain Research, Vol 3 (2022)

Ketamine is administered predominantly via the intravenous route for the various indications, including anesthesia, pain relief and treatment of depression. Here we report on the pharmacokinetics of sublingual and buccal fast-dissolving oral-thin-fil

Externí odkaz: https://doaj.org/article/891d0d1bc2c948f0a6c320480e54f1c7

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Inhaled Δ(9)-tetrahydrocannabinol does not enhance oxycodone-induced respiratory depression: randomised controlled trial in healthy volunteers

Autor: Cornelis Jan van Dam, Rutger van der Schrier, Monique van Velzen, Maarten van Lemmen, Pieter Simons, Kiki W.K. Kuijpers, Simone Jansen, Mikael A. Kowal, Erik Olofsen, Cornelis Kramers, Albert Dahan, Marieke Niesters

Publikováno v: British Journal of Anaesthesia, 130, 485-493
British Journal of Anaesthesia, 130, 4, pp. 485-493

Contains fulltext : 291652.pdf (Publisher’s version ) (Open Access) BACKGROUND: In humans, the effect of cannabis on ventilatory control is poorly studied, and consequently, the effect of Δ(9)-tetrahydrocannabinol (THC) remains unknown, particular

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89ca6df9a4f37f8a44c3cefd80d84a99
https://doi.org/10.1016/j.bja.2022.12.018

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Respiratory effects of biased-ligand oliceridine in older volunteers: a pharmacokinetic-pharmacodynamic comparison with morphine

Autor: Pieter Simons, Rutger van der Schrier, Maarten van Lemmen, Simone Jansen, Kiki W.K. Kuijpers, Monique van Velzen, Elise Sarton, Todd Nicklas, Cathy Michalsky, Mark A. Demitrack, Michael Fossler, Erik Olofsen, Marieke Niesters, Albert Dahan

Publikováno v: Anesthesiology.

Background Oliceridine is a G protein–biased µ-opioid, a drug class that is associated with less respiratory depression than nonbiased opioids, such as morphine. The authors quantified the respiratory effects of oliceridine and morphine in elderly

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::956798915a6ad6c567b96b56eae36242
https://pubmed.ncbi.nlm.nih.gov/36538359

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Effect of paroxetine or quetiapine combined with oxycodone vs oxycodone alone on ventilation during hypercapnia

Publikováno v: JAMA
Journal of the American Medical Association, 328(14), 1405-1414. AMER MEDICAL ASSOC

ImportanceOpioids can cause severe respiratory depression by suppressing feedback mechanisms that increase ventilation in response to hypercapnia. Following the addition of boxed warnings to benzodiazepine and opioid products about increased respirat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82cbc6db75c3d488ac4b58e8d63a09a8
https://hdl.handle.net/1887/3572119

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Are thyrotropin-releasing hormone (TRH) and analog taltirelin viable reversal agents of opioid-induced respiratory depression?

Autor: Marieke Hyke Algera, Joseph F. Cotten, Monique van Velzen, Marieke Niesters, Martijn Boon, Daniel S. Shoham, Kaye E. Dandrea, Rutger van der Schrier, Albert Dahan

Publikováno v: Pharmacology Research and Perspectives, 10(3). JOHN WILEY & SONS LTD

Opioid-induced respiratory depression (OIRD) is a potentially life-threatening complication of opioid consumption. Apart from naloxone, an opioid antagonist that has various disadvantages, a possible reversal strategy is treatment of OIRD with the hy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::527a340501442572c6b984f40073bbc3
https://doi.org/10.1002/prp2.974

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