Zobrazeno 1 - 10
of 365
pro vyhledávání: '"Rutger J. Ploeg"'
Autor:
Ka Ho Tam, Maria F. Soares, Jesper Kers, Edward J. Sharples, Rutger J. Ploeg, Maria Kaisar, Jens Rittscher
Publikováno v:
Frontiers in Transplantation, Vol 3 (2024)
Two common obstacles limiting the performance of data-driven algorithms in digital histopathology classification tasks are the lack of expert annotations and the narrow diversity of datasets. Multi-instance learning (MIL) can address the former chall
Externí odkaz:
https://doaj.org/article/74e5aa5558d74e47a75f886017bc349d
Autor:
Sevda Hassan, Lisa Mumford, Susan Robinson, Dora Foukanelli, Nick Torpey, Rutger J. Ploeg, Nizam Mamode, Michael F. Murphy, Colin Brown, David J. Roberts, Fiona Regan, Michelle Willicombe
Publikováno v:
Frontiers in Nephrology, Vol 3 (2023)
BackgroundPatient Blood Management (PBM), endorsed by the World Health Organisation is an evidence-based, multi-disciplinary approach to minimise inappropriate blood product transfusions. Kidney transplantation presents a particular challenge to PBM,
Externí odkaz:
https://doaj.org/article/d52319a301af444e911fac7f8425e290
Autor:
Alexander F. Schaapherder, Maria Kaisar, Lisa Mumford, Matthew Robb, Rachel Johnson, Michèle J.C. de Kok, Frederike J. Bemelman, Jacqueline van de Wetering, Arjan D. van Zuilen, Maarten H.L. Christiaans, Marije C. Baas, Azam S. Nurmohamed, Stefan P. Berger, Esther Bastiaannet, Aiko P.J. de Vries, Edward Sharples, Rutger J. Ploeg, Jan H.N. Lindeman
Publikováno v:
EClinicalMedicine, Vol 50, Iss , Pp 101516- (2022)
Summary: Background: Donor-characteristics and donor characteristics-based decision algorithms are being progressively used in the decision process whether or not to accept an available donor kidney graft for transplantation. While this may improve o
Externí odkaz:
https://doaj.org/article/d2baaec37baa4546b649edee0844daae
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Hypothermic machine perfusion (HMP) has become the new gold standard in clinical donor kidney preservation and a promising novel strategy in higher risk donor livers in several countries. As shown by meta-analysis for the kidney, HMP decreases the ri
Externí odkaz:
https://doaj.org/article/004238a09ee445b4a42cf3e872368a74
Autor:
Nicola J. Dyson, BSc, Nicole Kattner, PhD, Minna Honkanen-Scott, BSc, Bethany Hunter, MRes, Jennifer A. Doyle, MRes, Kathryn White, PhD, Tracey S. Davey, CSci, FRMS, Rutger J. Ploeg, FRCS, Yvonne A. Bury, MD, FRCPath, Dina G. Tiniakos, MD, FRCPath,, James A. M. Shaw, FRCP, William E. Scott, III, PhD
Publikováno v:
Transplantation Direct, Vol 8, Iss 1, p e1271 (2022)
Background. Pancreas and islet transplantation outcomes are negatively impacted by injury to the endocrine cells from acute stress during donor death, organ procurement, processing, and transplant procedures. Here, we report a novel electron microsco
Externí odkaz:
https://doaj.org/article/5668dbba4df24c0caec4a1538c9d794b
Autor:
Annemarie Weissenbacher, John P. Stone, Maria Letizia Lo Faro, James P. Hunter, Rutger J. Ploeg, Constantin C. Coussios, James E. Fildes, Peter J. Friend
Publikováno v:
Frontiers in Medicine, Vol 8 (2022)
Kidney transplantation is the best renal-replacement option for most patients with end-stage renal disease. Normothermic machine preservation (NMP) of the kidney has been studied extensively during the last two decades and implemented in clinical tri
Externí odkaz:
https://doaj.org/article/89bd6f784cbf4429b5cd60f1962ee65f
Autor:
Stina Lignell, MD, Stine Lohmann, MD, Kaithlyn M. Rozenberg, BSc, Henri G. D. Leuvenink, PhD, Merel B. F. Pool, MD, Kate R. Lewis, MSc, Cyril Moers, MD, PhD, James P. Hunter, MD, Bsc(hons), Rutger J. Ploeg, MD, PhD, Marco Eijken, PhD, Ulla Møldrup, MD, Søren Krag, PhD, Carla C. Baan, PhD, Bjarne Kuno Møller, MD, PhD, Anna Krarup Keller, MD, PhD, Bente Jespersen, MD, PhD
Publikováno v:
Transplantation Direct, Vol 7, Iss 2, p e653 (2021)
Background. In an era where global kidney shortage has pushed the field of transplantation towards using more marginal donors, modified kidney preservation techniques are currently being reviewed. Some techniques require further optimization before i
Externí odkaz:
https://doaj.org/article/73138ae31b854473b693b92164cb0996
Autor:
Richard Dumbill, Roderick Jaques, Matthew Robb, Rachel Johnson, Rutger J. Ploeg, Maria E. Kaisar, Edward J. Sharples
Publikováno v:
Journal of Clinical Medicine, Vol 11, Iss 8, p 2222 (2022)
Background: In kidney transplantation, the relative contribution of various donor, procedure and recipient-related factors on clinical outcomes is unknown. Previous paired studies have largely focused on examining factors predicting early outcomes, w
Externí odkaz:
https://doaj.org/article/47e54821671343c7a62bd49ea7ddf82b
Autor:
Monique I. Andersson, Carolina V. Arancibia-Carcamo, Kathryn Auckland, J. Kenneth Baillie, Eleanor Barnes, Tom Beneke, Sagida Bibi, Tim Brooks, Miles Carroll, Derrick Crook, Kate Dingle, Christina Dold, Louise O. Downs, Laura Dunn, David W. Eyre, Javier Gilbert Jaramillo, Heli Harvala, Sarah Hoosdally, Samreen Ijaz, Tim James, William James, Katie Jeffery, Anita Justice, Paul Klenerman, Julian C. Knight, Michael Knight, Xu Liu, Sheila F. Lumley, Philippa C. Matthews, Anna L. McNaughton, Alexander J. Mentzer, Juthathip Mongkolsapaya, Sarah Oakley, Marta S. Oliveira, Timothy Peto, Rutger J. Ploeg, Jeremy Ratcliff, Melanie J. Robbins, David J. Roberts, Justine Rudkin, Rebecca A. Russell, Gavin Screaton, Malcolm G. Semple, Donal Skelly, Peter Simmonds, Nicole Stoesser, Lance Turtle, Susan Wareing, Maria Zambon
Publikováno v:
Wellcome Open Research, Vol 5 (2020)
Background: Laboratory diagnosis of SARS-CoV-2 infection (the cause of COVID-19) uses PCR to detect viral RNA (vRNA) in respiratory samples. SARS-CoV-2 RNA has also been detected in other sample types, but there is limited understanding of the clinic
Externí odkaz:
https://doaj.org/article/f9d2890a0b4946daacbdd2537b6e05f6
Autor:
Emily R. Adams, Mark Ainsworth, Rekha Anand, Monique I. Andersson, Kathryn Auckland, J. Kenneth Baillie, Eleanor Barnes, Sally Beer, John I. Bell, Tamsin Berry, Sagida Bibi, Miles Carroll, Senthil K. Chinnakannan, Elizabeth Clutterbuck, Richard J. Cornall, Derrick W. Crook, Thushan de Silva, Wanwisa Dejnirattisai, Kate E. Dingle, Christina Dold, Alexis Espinosa, David W. Eyre, Helen Farmer, Maria Fernandez Mendoza, Dominique Georgiou, Sarah J. Hoosdally, Alastair Hunter, Katie Jefferey, Dominic F. Kelly, Paul Klenerman, Julian Knight, Clarice Knowles, Andrew J. Kwok, Ullrich Leuschner, Robert Levin, Chang Liu, César López-Camacho, Jose Martinez, Philippa C. Matthews, Hannah McGivern, Alexander J. Mentzer, Jonathan Milton, Juthathip Mongkolsapaya, Shona C. Moore, Marta S. Oliveira, Fiona Pereira, Elena Perez, Timothy Peto, Rutger J. Ploeg, Andrew Pollard, Tessa Prince, David J. Roberts, Justine K. Rudkin, Veronica Sanchez, Gavin R. Screaton, Malcolm G. Semple, Jose Slon-Campos, Donal T. Skelly, Elliot Nathan Smith, Alberto Sobrinodiaz, Julie Staves, David I. Stuart, Piyada Supasa, Tomas Surik, Hannah Thraves, Pat Tsang, Lance Turtle, A. Sarah Walker, Beibei Wang, Charlotte Washington, Nicholas Watkins, James Whitehouse, National COVID Testing Scientific Advisory Panel
Publikováno v:
Wellcome Open Research, Vol 5 (2020)
Background: The COVID-19 pandemic caused >1 million infections during January-March 2020. There is an urgent need for reliable antibody detection approaches to support diagnosis, vaccine development, safe release of individuals from quarantine, and p
Externí odkaz:
https://doaj.org/article/0c687b81cce14a638bcf5fb3706d76b6