Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Rutger D. Luteijn"'
Autor:
Rutger D. Luteijn, Patrique Praest, Frank Thiele, Saravanan Manikam Sadasivam, Katrin Singethan, Jan W. Drijfhout, Christian Bach, Steffen Matthijn de Boer, Robert J. Lebbink, Sha Tao, Markus Helfer, Nina C. Bach, Ulrike Protzer, Ana I. Costa, J. Antoinette Killian, Ingo Drexler, Emmanuel J. H. J. Wiertz
Publikováno v:
Cells, Vol 9, Iss 9, p 1989 (2020)
The ongoing threat of viral infections and the emergence of antiviral drug resistance warrants a ceaseless search for new antiviral compounds. Broadly-inhibiting compounds that act on elements shared by many viruses are promising antiviral candidates
Externí odkaz:
https://doaj.org/article/58bd89e9563747248b0b2cd4d22db3fd
Autor:
Rutger D. Luteijn, Sypke R. van Terwisga, Jill E. Ver Eecke, Liberty Onia, Shivam A. Zaver, Joshua J Woodward, David H. Raulet, Frank J.M. van Kuppeveld
STING induces transcription of pro-inflammatory genes upon activation at the Golgi apparatus. Many of the regulators involved in STING activation are unknown. We found that ACBD3 and other phosphatidylinositol 4-phosohate (PI4P) regulating proteins p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d8a8d6f2315df0bc60ec8972c46014e3
https://doi.org/10.1101/2022.10.17.512580
https://doi.org/10.1101/2022.10.17.512580
Publikováno v:
Nature microbiology. 7(5)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bd9f9dee19bbd04fbe7b915de9571aa9
https://pubmed.ncbi.nlm.nih.gov/35301296
https://pubmed.ncbi.nlm.nih.gov/35301296
Autor:
Marieke C Verweij, Daniëlle Horst, Bryan D Griffin, Rutger D Luteijn, Andrew J Davison, Maaike E Ressing, Emmanuel J H J Wiertz
Publikováno v:
PLoS Pathogens, Vol 11, Iss 4, p e1004743 (2015)
Herpesviruses are large DNA viruses that are highly abundant within their host populations. Even in the presence of a healthy immune system, these viruses manage to cause lifelong infections. This persistence is partially mediated by the virus enteri
Externí odkaz:
https://doaj.org/article/53438da65fdd4d49ba4bffa4d8db3293
Autor:
Jan W. Drijfhout, Rutger D. Luteijn, Marianne Boes, Lotte Spel, Emmanuel J. H. J. Wiertz, Stefan Nierkens
Publikováno v:
Immunology and Cell Biology
Immunology and Cell Biology, 96(2), 137. Nature Publishing Group
Immunology and Cell Biology, 96(2), 137-148
Immunology and Cell Biology, 96(2), 137. Nature Publishing Group
Immunology and Cell Biology, 96(2), 137-148
Viruses may interfere with the MHC class I antigen presentation pathway in order to avoid CD8+ T cell-mediated immunity. A key target within this pathway is the peptide transporter TAP. This transporter plays a central role in MHC class I-mediated pe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a6dac482d4ff7258d9138996518e234
https://doi.org/10.1111/imcb.1024
https://doi.org/10.1111/imcb.1024
Autor:
Liberty Onia, George E. Katibah, David H. Raulet, Sarah M. McWhirter, Jacob E. Corn, Stacia K. Wyman, Rutger D. Luteijn, Benjamin G. Gowen, Nicholas E Garelis, Joshua J. Woodward, Shivam A. Zaver
The accumulation of DNA in the cytosol serves as a key immunostimulatory signal associated with infections, cancer and genomic damage1,2. Cytosolic DNA triggers immune responses by activating the cGAS/STING pathway3. The binding of DNA to the cytosol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9122fb8019359118712cec72bce36f36
Autor:
Toin H. van Kuppevelt, Emmanuel J. H. J. Wiertz, Rutger D. Luteijn, Ingo Drexler, Robert Jan Lebbink, Ingrid G. J. Boer, Vincent A. Blomen, Ferdy R. van Diemen, Saravanan Manikam Sadasivam, Thijn R. Brummelkamp
Publikováno v:
Journal of Virology
Journal of Virology, 93(13). American Society for Microbiology
Journal of Virology, 93
Journal of Virology, 93, 13
Journal of Virology, 93(13). American Society for Microbiology
Journal of Virology, 93
Journal of Virology, 93, 13
Contains fulltext : 205154.pdf (Publisher’s version ) (Closed access) Vaccinia virus is a promising viral vaccine and gene delivery candidate and has historically been used as a model to study poxvirus-host cell interactions. We employed a genome-w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47ae9e481dbde429823b6a96365bc373
https://doi.org/10.1128/JVI.02160-18
https://doi.org/10.1128/JVI.02160-18
Autor:
Małgorzata Graul, Emmanuel J. H. J. Wiertz, Andrea D. Lipińska, Krystyna Bieńkowska-Szewczyk, Aleksandra W Babnis, Rutger D. Luteijn, Patrique Praest, Magda Wąchalska
Publikováno v:
Cells
Cells, 8(12)
Volume 8
Issue 12
Cells, 8(12)
Volume 8
Issue 12
Transporter associated with antigen processing (TAP), a key player in the major histocompatibility complex class I-restricted antigen presentation, makes an attractive target for viruses that aim to escape the immune system. Mechanisms of TAP inhibit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::319c072841ae27c4d572d049578558eb
Autor:
Ingo Drexler, Robert Jan Lebbink, Emmanuel J. H. J. Wiertz, Toin H. van Kuppevelt, Ferdy R. van Diemen, Vincent A. Blomen, Thijn R. Brummelkamp, Rutger D. Luteijn, Ingrid G. J. Boer, Saravanan Manikam Sadasivam
Vaccinia virus is a promising viral vaccine and gene delivery candidate, and has historically been used as a model to study poxvirus-host cell interactions. We employed a genome-wide insertional mutagenesis approach in human haploid cells to identify
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c6725a093e77ca4cee5e54663e534fc
https://doi.org/10.1101/493205
https://doi.org/10.1101/493205
Autor:
Shivam A. Zaver, Stacia K. Wyman, Joshua J. Woodward, Liberty Onia, Nicholas E Garelis, Jacob E. Corn, Rutger D. Luteijn, Benjamin G. Gowen, Sarah M. McWhirter, David H. Raulet, George E. Katibah
Publikováno v:
Nature. 579:E12-E12
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d6c0d9a81c2777a78e6253cee4b60930
https://doi.org/10.1038/s41586-020-2064-8
https://doi.org/10.1038/s41586-020-2064-8