Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Rute M Pinto"'
Autor:
Colin P Sharp, Beth H Thompson, Tessa J Nash, Ola Diebold, Rute M Pinto, Luke Thorley, Yao-Tang Lin, Samantha Sives, Helen Wise, Sara Clohisey Hendry, Finn Grey, Lonneke Vervelde, Peter Simmonds, Paul Digard, Eleanor R Gaunt
Publikováno v:
PLoS Pathogens, Vol 19, Iss 5, p e1011357 (2023)
Synonymous recoding of RNA virus genomes is a promising approach for generating attenuated viruses to use as vaccines. Problematically, recoding typically hinders virus growth, but this may be rectified using CpG dinucleotide enrichment. CpGs are rec
Externí odkaz:
https://doaj.org/article/6c1353e296d148f5a88dfc35be436326
Autor:
Vanessa Herder, Kieran Dee, Joanna K Wojtus, Ilaria Epifano, Daniel Goldfarb, Christoforos Rozario, Quan Gu, Ana Da Silva Filipe, Kyriaki Nomikou, Jenna Nichols, Ruth F Jarrett, Andrew Stevenson, Steven McFarlane, Meredith E Stewart, Agnieszka M Szemiel, Rute M Pinto, Andreu Masdefiol Garriga, Chris Davis, Jay Allan, Sheila V Graham, Pablo R Murcia, Chris Boutell
Publikováno v:
PLoS Biology, Vol 19, Iss 12, p e3001065 (2021)
The pandemic spread of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), the etiological agent of Coronavirus Disease 2019 (COVID-19), represents an ongoing international health crisis. A key symptom of SARS-CoV-2 infection is the onset o
Externí odkaz:
https://doaj.org/article/b2e9ec132cad418992b3f020afee74ab
Autor:
Carina F. Pereira, Helen M. Wise, Dominic Kurian, Rute M. Pinto, Maria J. Amorim, Andrew C. Gill, Paul Digard
Publikováno v:
BMC Research Notes, Vol 11, Iss 1, Pp 1-7 (2018)
Abstract Objective The multifunctional NS1 protein of influenza A virus has roles in antagonising cellular innate immune responses and promoting viral gene expression. To better understand the interplay between these functions, we tested the effects
Externí odkaz:
https://doaj.org/article/6329a0af670d4acdafdd3a57ac493b7d
Autor:
Colin P Sharp, Beth H Thompson, Tessa J Nash, Ola Diebold, Rute M Pinto, Luke Thorley, Yao-Tang Lin, Samantha Sives, Helen Wise, Sara Clohisey Hendry, Finn Grey, Lonneke Vervelde, Peter Simmonds, Paul Digard, Eleanor R Gaunt
Publikováno v:
Sharp, C P, Thompson, B H, Nash, T J, Diebold, O, Pinto, R M, Thorley, L, Lin, Y-T, Sives, S, Wise, H, Clohisey Hendry, S, Grey, F, Vervelde, L, Simmonds, P, Digard, P & Gaunt, E R 2023, ' CpG dinucleotide enrichment in the influenza A virus genome as a live attenuated vaccine development strategy ', PLoS Pathogens, vol. 19, no. 5, e1011357, pp. 1-34 . https://doi.org/10.1371/journal.ppat.1011357
Synonymous recoding of RNA virus genomes is a promising approach for generating attenuated viruses to use as vaccines. Problematically, recoding typically hinders virus growth, but this may be rectified using CpG dinucleotide enrichment. CpGs are rec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7f0e8cd1673b92293ecd43eb8616458
https://doi.org/10.1101/2022.04.29.490024
https://doi.org/10.1101/2022.04.29.490024
Autor:
Vanessa Herder, Kieran Dee, Joanna K. Wojtus, Ilaria Epifano, Daniel Goldfarb, Christoforos Rozario, Quan Gu, Ana Da Silva Filipe, Kyriaki Nomikou, Jenna Nichols, Ruth F. Jarrett, Andrew Stevenson, Steven McFarlane, Meredith E. Stewart, Agnieszka M. Szemiel, Rute M. Pinto, Andreu Masdefiol Garriga, Chris Davis, Jay Allan, Sheila V. Graham, Pablo R. Murcia, Chris Boutell
Publikováno v:
PLoS Biology
PLoS Biology, Vol 19, Iss 12, p e3001065 (2021)
PLoS Biology, Vol 19, Iss 12, p e3001065 (2021)
The pandemic spread of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), the etiological agent of Coronavirus Disease 2019 (COVID-19), represents an ongoing international health crisis. A key symptom of SARS-CoV-2 infection is the onset o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47b048f3b47fcb4bddb8de28de3421b4
https://pubmed.ncbi.nlm.nih.gov/34932557
https://pubmed.ncbi.nlm.nih.gov/34932557