Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Rustem Khusainov"'
Autor:
Rustem Khusainov, Oscar P. Kuipers
Publikováno v:
PLoS ONE, Vol 9, Iss 4 (2014)
Externí odkaz:
https://doaj.org/article/eaf0b4a7260c4b59ad5d7ab0410e8579
Autor:
Rustem Khusainov, Oscar P Kuipers
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e74890 (2013)
Precursor nisin is a model posttranslationally modified precursor lantibiotic that can be structurally divided into a leader peptide sequence and a modifiable core peptide part. The nisin core peptide clearly plays an important role in the precursor
Externí odkaz:
https://doaj.org/article/1ca98bae8e734970ac2c14113c0e06c9
Publikováno v:
Molecular Microbiology. 82:706-718
Summary Although nisin is a model lantibiotic, our knowledge of the specific interactions of prenisin with its modi- fication enzymes remains fragmentary. Here, we dem- onstrate that the nisin modification enzymes NisB and NisC can be pulled down in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc097f94c52c9a2f02ebdcdeb5ff7bcc
https://doi.org/10.1111/j.1365-2958.2011.07846.x
https://doi.org/10.1111/j.1365-2958.2011.07846.x
Publikováno v:
The Journal of Biological Chemistry, 284(38), 25962-25972. AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC
The lantibiotic nisin is a potent antimicrobial substance, which contains unusual lanthionine rings and dehydrated amino acid residues and is produced by Lactococcus lactis. Recently, the nisin biosynthetic machinery has been applied to introduce lan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9217255bb11de4683f88104e5a96b234
https://doi.org/10.1074/jbc.m109.026690
https://doi.org/10.1074/jbc.m109.026690
Publikováno v:
Cellular and molecular life sciences. 65(3):455-476
This review discusses the state-of-the-art in molecular research on the most prominent and widely applied lantibiotic, i.e., nisin. The developments in understanding its complex biosynthesis and mode of action are highlighted. Moreover, novel applica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5dffd2f72f2920a145a37eef6ed7cd3
https://hdl.handle.net/11370/a5cca0a7-d24f-4f45-9da8-79561530fc8a
https://hdl.handle.net/11370/a5cca0a7-d24f-4f45-9da8-79561530fc8a
Publikováno v:
FEBS Open Bio
FEBS Open Bio, 3, 237-242. Wiley-Blackwell
FEBS Open Bio, 3, 237-242. Wiley-Blackwell
Nisin is the most prominent and applied bacteriocin that serves as a model for class I lantibiotics. The nisin leader peptide importantly determines interactions between precursor nisin and its modification enzymes NisB and NisC that mature nisin pos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce93e8a564f48f7287b9fadb3871ef44
http://hdl.handle.net/10044/1/12952
http://hdl.handle.net/10044/1/12952
Autor:
Oscar P. Kuipers, Rustem Khusainov
Publikováno v:
ChemBioChem, 13(16), 2433-2438. WILEY-V C H VERLAG GMBH
The nisin leader is believed to be crucial for nisin biosynthesis. Here, by using a construct completely lacking the leader peptide, we show that an up to fivefold-dehydrated leaderless prenisin can be obtained, as judged by MALDI-TOF MS, and that so
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3d1cff94e12b29a0ef635fb0e0c238e
https://research.rug.nl/en/publications/e3d40a23-92a2-4dec-a1c0-72de3c653675
https://research.rug.nl/en/publications/e3d40a23-92a2-4dec-a1c0-72de3c653675
Autor:
Manyu Li, Lukasz Jaroszynski, Gerald Wulf, Monika Korabiowska, Iris Schwandt, Rustem Khusainov, Wolfgang Engel, H. W. Michelmann, Andreas Meinhardt, Karim Nayernia
Publikováno v:
Human molecular genetics. 13(14)
Infertility affects 13-18% of couples and growing evidence from clinical and epidemiological studies suggests an increasing incidence of male reproductive problems. There is a male factor involved in up to half of all infertile couples. The pathogene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c688adf8d7625879e65418ce6d405031
https://pubmed.ncbi.nlm.nih.gov/15163638
https://pubmed.ncbi.nlm.nih.gov/15163638