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A Novel Mutation in LXRα Uncovers a Role for Cholesterol Sensing in Limiting Metabolic Dysfunction-Associated Steatohepatitis (MASH).

Autor: Clark AT; Department of Pharmacology, University of Virginia School of Medicine, Charlottesville, Virginia.; These authors contributed equally to the work., Russo-Savage L; Department of Pharmacology, University of Virginia School of Medicine, Charlottesville, Virginia.; These authors contributed equally to the work.; Current address: Department of Neurological Sciences, University of Vermont, Burlington, Vermont., Ashton LA; Department of Pharmacology, University of Virginia School of Medicine, Charlottesville, Virginia., Haghshenas N; Department of Pharmacology, University of Virginia School of Medicine, Charlottesville, Virginia., Schulman IG; Department of Pharmacology, University of Virginia School of Medicine, Charlottesville, Virginia.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 May 15. Date of Electronic Publication: 2024 May 15.