Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Russell W Goetze"'
Autor:
Joseph A Hollenbaugh, Jadd Shelton, Sijia Tao, Sheida Amiralaei, Peng Liu, Xiao Lu, Russell W Goetze, Longhu Zhou, James H Nettles, Raymond F Schinazi, Baek Kim
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0169052 (2017)
SAMHD1 hydrolyzes 2'-deoxynucleoside-5'-triphosphates (dNTPs) into 2'-deoxynucleosides and inorganic triphosphate products. In this paper, we evaluated the impact of 2' sugar moiety substitution for different nucleotides on being substrates for SAMHD
Externí odkaz:
https://doaj.org/article/7585f5c3a1dc4457859860a505db1ff0
Publikováno v:
The Journal of Biological Chemistry
Retrovirus integration into the host genome relies on several host enzymes, potentially including DNA polymerase β (Pol β). However, whether human Pol β is essential for lentivirus replication in human cells is unclear. Here, we abolished DNA poly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06ed89f5217489abde6a635fdabaead0
http://europepmc.org/articles/PMC5572920
http://europepmc.org/articles/PMC5572920
Autor:
Fadlo R. Khuri, Haian Fu, Andrei A. Ivanov, Qi Qi, Sydney Bell, Xiulei Mo, Yin Luo, Qiankun Niu, Margaret A. Johns, Yuhong Du, Jonathan J. Havel, Lee Cooper, Carlos S. Moreno, Russell W. Goetze
Publikováno v:
Molecular Pharmacology. 91:339-347
The c-Myc (MYC) transcription factor is a major cancer driver and a well-validated therapeutic target. However, directly targeting MYC has been challenging. Thus, identifying proteins that interact with and regulate MYC may provide alternative strate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8517b9011bec95d5d8ec743cbcc9dd9b
https://doi.org/10.1124/mol.116.107623
https://doi.org/10.1124/mol.116.107623
Autor:
Richard M. Walsh, Phillip G. Gross, William B. Peeples, Zachary A. Wood, Joseph E. Sanchez, Russell W. Goetze
Publikováno v:
Biochemistry. 54:3360-3369
Ketopantoate reductase (KPR) catalyzes the NADPH-dependent production of pantoate, an essential precursor in the biosynthesis of coenzyme A. Previous structural studies have been limited to Escherichia coli KPR, a monomeric enzyme that follows a sequ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69336f4679bfed0f35d7404cd846f756
https://doi.org/10.1021/acs.biochem.5b00174
https://doi.org/10.1021/acs.biochem.5b00174
Autor:
Sheida Amiralaei, Raymond F. Schinazi, Jadd R. Shelton, Longhu Zhou, Russell W. Goetze, Joseph A. Hollenbaugh, Xiao Lu, James H. Nettles, Sijia Tao, Baek Kim, Peng Liu
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0169052 (2017)
PLoS ONE
PLoS ONE
SAMHD1 hydrolyzes 2'-deoxynucleoside-5'-triphosphates (dNTPs) into 2'-deoxynucleosides and inorganic triphosphate products. In this paper, we evaluated the impact of 2' sugar moiety substitution for different nucleotides on being substrates for SAMHD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::beb1dc46bf9ba6274be1dbd210a13468
http://europepmc.org/articles/PMC5207538?pdf=render
http://europepmc.org/articles/PMC5207538?pdf=render