Zobrazeno 1 - 10
of 116
pro vyhledávání: '"Russell Tupling A"'
Autor:
Laetitia Marcadet, Emma Sara Juracic, Nasrin Khan, Zineb Bouredji, Hideo Yagita, Leanne M. Ward, A. Russell Tupling, Anteneh Argaw, Jérôme Frenette
Publikováno v:
Cells, Vol 12, Iss 11, p 1538 (2023)
Cardiomyopathy has become one of the leading causes of death in patients with Duchenne muscular dystrophy (DMD). We recently reported that the inhibition of the interaction between the receptor activator of nuclear factor κB ligand (RANKL) and recep
Externí odkaz:
https://doaj.org/article/f84e8a13eaa1491a9132c9c16aed8604
Autor:
Sébastien S. Dufresne, Antoine Boulanger-Piette, Sabrina Bossé, Anteneh Argaw, Dounia Hamoudi, Laetitia Marcadet, Daniel Gamu, Val A. Fajardo, Hideo Yagita, Josef M. Penninger, A. Russell Tupling, Jérôme Frenette
Publikováno v:
Acta Neuropathologica Communications, Vol 6, Iss 1, Pp 1-10 (2018)
Abstract Although there is a strong association between osteoporosis and skeletal muscle atrophy/dysfunction, the functional relevance of a particular biological pathway that regulates synchronously bone and skeletal muscle physiopathology is still e
Externí odkaz:
https://doaj.org/article/d6a955d588f542a5832283a8bbb9b39b
Publikováno v:
Lipids in Health and Disease, Vol 17, Iss 1, Pp 1-8 (2018)
Abstract Background An increase in phosphatidylcholine:phosphatidylethanolamine (PC:PE) and a decrease in fatty acyl chain length, monounsaturated:polyunsaturated (MUFA:PUFA) fatty acyl ratio reduces SERCA activity in liposomes and in mouse models of
Externí odkaz:
https://doaj.org/article/416d17418a164cc491450f01adf87687
Autor:
Emily B. Mardian, Ryan M. Bradley, Juan J. Aristizabal Henao, Phillip M. Marvyn, Katherine A. Moes, Eric Bombardier, A. Russell Tupling, Ken D. Stark, Robin E. Duncan
Publikováno v:
Journal of Lipid Research, Vol 58, Iss 10, Pp 2037-2050 (2017)
Acylglycerophosphate acyltransferase 4 (AGPAT4)/lysophosphatidic acid acyltransferase delta catalyzes the formation of phosphatidic acid (PA), a precursor of triacylglycerol (TAG). We investigated the effect of Agpat4 gene ablation on white adipose
Externí odkaz:
https://doaj.org/article/572c0f3f918d40c68195d7d3f8e36fb8
Autor:
Frenette, Laetitia Marcadet, Emma Sara Juracic, Nasrin Khan, Zineb Bouredji, Hideo Yagita, Leanne M. Ward, A. Russell Tupling, Anteneh Argaw, Jérôme
Publikováno v:
Cells; Volume 12; Issue 11; Pages: 1538
Cardiomyopathy has become one of the leading causes of death in patients with Duchenne muscular dystrophy (DMD). We recently reported that the inhibition of the interaction between the receptor activator of nuclear factor κB ligand (RANKL) and recep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::46595b8af144f58aaad60d0634429612
Publikováno v:
Physiology. 38
The sarco(endo)plasmic reticulum Ca2+-ATPases (SERCAs) are responsible for inducing muscle relaxation and are integral to the maintenance of intracellular calcium (Ca2+) homeostasis. As such, their activity is modulated by multiple regulatory protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c5fd717dd4d6beeff119d8e8de8ba16
https://doi.org/10.1152/physiol.2023.38.s1.5735123
https://doi.org/10.1152/physiol.2023.38.s1.5735123
Publikováno v:
Physiology. 38
Sarcolipin (SLN), a small protein inhibitor of the sarco(endo)plasmic reticulum Ca2+-ATPase (SERCA), is dynamically upregulated in atrophic unloading and disease states where it promotes muscle health by activating calcineurin (Cn) and the dephosphor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cfd1708dafbf2734c1251007c1e40e6d
https://doi.org/10.1152/physiol.2023.38.s1.5735129
https://doi.org/10.1152/physiol.2023.38.s1.5735129
Publikováno v:
American Journal of Physiology-Cell Physiology. 322:C382-C394
Sarcolipin (SLN) is a small regulatory protein that inhibits the sarco(endo)plasmic reticulum Ca2+-ATPase (SERCA) pump. When bound to SERCA, SLN reduces the apparent Ca2+ affinity of SERCA and uncouples SERCA Ca2+ transport from its ATP consumption.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a2f164b14582a59cdf2035fdb3a3730
https://doi.org/10.1152/ajpcell.00198.2021
https://doi.org/10.1152/ajpcell.00198.2021
Autor:
Val A. Fajardo, Eric Bombardier, Elliott McMillan, Khanh Tran, Brennan J. Wadsworth, Daniel Gamu, Andrew Hopf, Chris Vigna, Ian C. Smith, Catherine Bellissimo, Robin N. Michel, Mark A. Tarnopolsky, Joe Quadrilatero, A. Russell Tupling
Publikováno v:
Disease Models & Mechanisms, Vol 8, Iss 8, Pp 999-1009 (2015)
Centronuclear myopathy (CNM) is a congenital myopathy that is histopathologically characterized by centrally located nuclei, central aggregation of oxidative activity, and type I fiber predominance and hypotrophy. Here, we obtained commercially avail
Externí odkaz:
https://doaj.org/article/5c1b60ecd4ac4318a37bb7998cf58ece
Publikováno v:
Bioscience Reports. 42
In healthy muscle, the rapid release of calcium ions (Ca2+) with excitation–contraction (E-C) coupling, results in elevations in Ca2+ concentrations which can exceed 10-fold that of resting values. The sizable transient changes in Ca2+ concentratio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fda9f4c737a6573efc879b91eb8651e
https://doi.org/10.1042/bsr20211997
https://doi.org/10.1042/bsr20211997