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of 19
pro vyhledávání: '"Russell Snyder"'
Autor:
Upendra Gumaste, Sivaramakrishna Koganti, Thomas J. Thekkumkara, Vardan T. Karamyan, Russell Snyder
Publikováno v:
European Journal of Pharmacology. 723:131-140
Controlling angiotensin AT1 receptor function has been shown to be protective for many pathophysiological disorders. Although estrogen metabolite, 2-methoxyestradiol (2ME2) can down-regulate angiotensin AT1 receptor expression independently of nuclea
Publikováno v:
Methods in Molecular Biology ISBN: 9781493931262
The role of 2-methoxyestradiol is becoming a major area of investigation because of its therapeutic utility, though its mechanism is not fully explored. Recent studies have identified the G-protein-coupled receptor 30 (GPR30, GPER) as a high-affinity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb8e1d80239110e5f5f6a98ccf2aed4e
https://doi.org/10.1007/978-1-4939-3127-9_2
https://doi.org/10.1007/978-1-4939-3127-9_2
Publikováno v:
American Journal of Physiology-Renal Physiology. 303:F766-F774
Previously, we have demonstrated human angiotensin type 1 receptor (hAT1R) promoter architecture with regard to the effect of high glucose (25 mM)-mediated transcriptional repression in human proximal tubule epithelial cells (hPTEC; Thomas BE, Thekku
Publikováno v:
Gender Medicine. 9:76-93
Background Delayed onset of cardiovascular disease (CVD) in female patients is not well understood, but could be due in part to the protective effect of estrogen before menopause. Experimental studies have identified the angiotensin type 1 receptor (
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1366
The role of 2-methoxyestradiol is becoming a major area of investigation because of its therapeutic utility, though its mechanism is not fully explored. Recent studies have identified the G-protein-coupled receptor 30 (GPR30, GPER) as a high-affinity
Autor:
Russell Snyder, Thomas J. Thekkumkara
Publikováno v:
Journal of Molecular Endocrinology. 48:99-114
Transcriptional repression throughcis- andtrans-acting factors enabling an alternate approach to control angiotensin type 1 receptor (AT1 or AGTR1 as listed in the MGI database) expression has not been studied. In previous investigations, treatment w
Publikováno v:
Clinical and Experimental Pharmacology and Physiology. 38:846-853
1. Literature data suggest that the electron-donating enzyme, cytochrome P450 reductase (CPR), might act as a source of reactive oxygen species (ROS). However, the role of CPR in pathophysiological conditions associated with oxidative stress is unkno
Autor:
Leslie Anne Morrison, Jeffrey Buchhalter, Gregory K. Yim, Roberto Caraballo, Judy Nation, Shlomo Shinnar, David A. Griesemer, Juergen Schreck, Carmela Tardo, Eric H. Kossoff, Agustin Legido, Y.M. Christiana Liu, Russell Snyder, Roger Larson, Anne E. Anderson, J. Helen Cross, Jong M. Rho, Bruce A. Cohen, James W. Wheless, Per Åmark, Heidi H. Pfeifer, Edward Kovnar, Pierangelo Veggiotti, Leon Dure, Colette Parker, Douglas R. Nordli, Elaine C. Wirrell, Robyn Blackford, Eileen P.G. Vining, J. Ben Renfroe, G. Dean Timmons, Elizabeth A. Thiele, Brian Grabert, Mary Currey, Carl E. Stafstrom, A. G. Christina Bergqvist, Beth Zupec-Kania, Heung Dong Kim, Michael Goldstein, Joerg Klepper, Diane Donley, Bhuwan P. Garg, Maria Dahlin, Rana S. Jehle, Zahava Turner, Elizabeth J. Donner, Karen Ballaban-Gil
Publikováno v:
Epilepsia. 50:304-317
The ketogenic diet (KD) is an established, effective nonpharmacologic treatment for intractable childhood epilepsy. The KD is provided differently throughout the world, with occasionally significant variations in its administration. There exists a ne
Autor:
Russell Snyder
“[A] personal and philosophical look at the war... clean and descriptive from a psychological operations specialist and Bronze Star Medal recipient (Great Falls Tribune). This is a true story of war—the story of one man's transformation as he ret
Autor:
Thomas J. Thekkumkara, Russell Snyder
Publikováno v:
Journal of molecular endocrinology. 50(3)
Recently, we have demonstrated that 13-cisretinoic acid (13cRA) downregulates rat angiotensin type 1A receptor (Agtr1a) gene transcription through a MAP kinase (ERK1/2)-dependent mechanism in rat liver epithelial and aortic smooth muscle cells. Howev