Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Russell P Swift"'
Publikováno v:
eLife, Vol 12 (2023)
Iron-sulfur clusters (FeS) are ancient and ubiquitous protein cofactors that play fundamental roles in many aspects of cell biology. These cofactors cannot be scavenged or trafficked within a cell and thus must be synthesized in any subcellular compa
Externí odkaz:
https://doaj.org/article/ce09e69f61c844f6bb4baf8d10bceb19
Autor:
Megan Okada, Krithika Rajaram, Russell P Swift, Amanda Mixon, John Alan Maschek, Sean T Prigge, Paul A Sigala
Publikováno v:
eLife, Vol 11 (2022)
Isopentenyl pyrophosphate (IPP) is an essential metabolic output of the apicoplast organelle in Plasmodium falciparum malaria parasites and is required for prenylation-dependent vesicular trafficking and other cellular processes. We have elucidated a
Externí odkaz:
https://doaj.org/article/d6c5aa846c6547d3ac466ffd5e45ea8e
Autor:
Russell P Swift, Krithika Rajaram, Cyrianne Keutcha, Hans B Liu, Bobby Kwan, Amanda Dziedzic, Anne E Jedlicka, Sean T Prigge
Publikováno v:
eLife, Vol 9 (2020)
The apicoplast of Plasmodium falciparum parasites is believed to rely on the import of three-carbon phosphate compounds for use in organelle anabolic pathways, in addition to the generation of energy and reducing power within the organelle. We genera
Externí odkaz:
https://doaj.org/article/8ba230931280402babefe27f33d8cdda
Autor:
Russell P Swift, Krithika Rajaram, Hans B Liu, Amanda Dziedzic, Anne E Jedlicka, Aleah D Roberts, Krista A Matthews, Hugo Jhun, Namandje N Bumpus, Shivendra G Tewari, Anders Wallqvist, Sean T Prigge
Publikováno v:
PLoS Pathogens, Vol 16, Iss 2, p e1008316 (2020)
Malaria parasites rely on a plastid organelle for survival during the blood stages of infection. However, the entire organelle is dispensable as long as the isoprenoid precursor, isopentenyl pyrophosphate (IPP), is supplemented in the culture medium.
Externí odkaz:
https://doaj.org/article/ae89fcfe1c5546e892dac3f249d96b6d
Publikováno v:
mBio, Vol 13, Iss 1 (2022)
ABSTRACT Ferredoxin (Fd) and ferredoxin-NADP+ reductase (FNR) form a redox system that is hypothesized to play a central role in the maintenance and function of the apicoplast organelle of malaria parasites. The Fd/FNR system provides reducing power
Externí odkaz:
https://doaj.org/article/af95598f7f9641da8698830ee3641551
Publikováno v:
Malaria Journal, Vol 19, Iss 1, Pp 1-18 (2020)
Abstract Background Human blood cells (erythrocytes) serve as hosts for the malaria parasite Plasmodium falciparum during its 48-h intraerythrocytic developmental cycle (IDC). Established in vitro protocols allow for the study of host–parasite inte
Externí odkaz:
https://doaj.org/article/e9ba33ec6fd74fa4b1856f7a74652a3d
Publikováno v:
eLife. 12
Iron-sulfur clusters (FeS) are ancient and ubiquitous protein cofactors that play fundamental roles in many aspects of cell biology. These cofactors cannot be scavenged or trafficked within a cell and thus must be synthesized in any subcellular compa
Iron sulfur clusters (FeS) are ancient and ubiquitous protein cofactors that play fundamental roles in many aspects of cell biology. These cofactors cannot be scavenged or trafficked within a cell and thus must be synthesized in any subcellular compa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::afcdcf45301f3809b0ca75947294f880
https://doi.org/10.1101/2022.10.31.514511
https://doi.org/10.1101/2022.10.31.514511