Zobrazeno 1 - 10
of 861
pro vyhledávání: '"Russell P, Tracy"'
Autor:
Alana C. Jones, Amit Patki, Vinodh Srinivasasainagendra, Bertha A. Hidalgo, Hemant K. Tiwari, Nita A. Limdi, Nicole D. Armstrong, Ninad S. Chaudhary, Bré Minniefield, Devin Absher, Donna K. Arnett, Leslie A. Lange, Ethan M. Lange, Bessie A. Young, Clarissa J. Diamantidis, Stephen S. Rich, Josyf C. Mychaleckyj, Jerome I. Rotter, Kent D. Taylor, Holly J. Kramer, Russell P. Tracy, Peter Durda, Silva Kasela, Tuuli Lappalinen, Yongmei Liu, W. Craig Johnson, David J. Van Den Berg, Nora Franceschini, Simin Liu, Charles P. Mouton, Parveen Bhatti, Steve Horvath, Eric A. Whitsel, Marguerite R. Irvin
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Chronic kidney disease (CKD) impacts about 1 in 7 adults in the United States, but African Americans (AAs) carry a disproportionately higher burden of disease. Epigenetic modifications, such as DNA methylation at cytosine-phosphate-guanine (
Externí odkaz:
https://doaj.org/article/12deb3d0ae334de99921176e9c1f291a
Autor:
Kent D. Taylor, Alexis C. Wood, Jerome I. Rotter, Xiuqing Guo, David M. Herrington, W. Craig Johnson, Wendy S. Post, Russell P. Tracy, Stephen S. Rich, Shaista Malik
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 19 (2024)
Background Inflammation is a feature of coronary heart disease (CHD), but the role of proinflammatory microbial infection in CHD remains understudied. Methods and Results CHD was defined in the MESA (Multi‐Ethnic Study of Atherosclerosis) as myocar
Externí odkaz:
https://doaj.org/article/d6727c8340ab42e88396ccacf2804528
Autor:
John S. Kim, Yifei Sun, Pallavi Balte, Mary Cushman, Rebekah Boyle, Russell P. Tracy, Linda M. Styer, Taison D. Bell, Michaela R. Anderson, Norrina B. Allen, Pamela J. Schreiner, Russell P. Bowler, David A. Schwartz, Joyce S. Lee, Vanessa Xanthakis, Margaret F. Doyle, Elizabeth A. Regan, Barry J. Make, Alka M. Kanaya, Sally E. Wenzel, Josef Coresh, Carmen R. Isasi, Laura M. Raffield, Mitchell S. V. Elkind, Virginia J. Howard, Victor E. Ortega, Prescott Woodruff, Shelley A. Cole, Joel M. Henderson, Nicholas J. Mantis, Monica M. Parker, Ryan T. Demmer, Elizabeth C. Oelsner
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract This study investigates correlates of anti-S1 antibody response following COVID-19 vaccination in a U.S. population-based meta-cohort of adults participating in longstanding NIH-funded cohort studies. Anti-S1 antibodies were measured from dr
Externí odkaz:
https://doaj.org/article/70812139a43e4ea6855d4d113d776773
Autor:
Rhys W. Niedecker, Joseph A. Delaney, Margaret F. Doyle, Andrew D. Sparks, Colleen M. Sitlani, Petra Buzkova, Irfan Zeb, Russell P. Tracy, Bruce M. Psaty, Matthew J. Budoff, Nels C. Olson
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundCirculating immune cells have gained interest as biomarkers of hepatic steatosis. Data on the relationships between immune cell subsets and early-stage steatosis in population-based cohorts are limited.MethodsThis study included 1,944 asymp
Externí odkaz:
https://doaj.org/article/a89e965518b34db585cca8b841d39fc6
Autor:
Xiaowei Hu, Jeongok G. Logan, Younghoon Kwon, Joao A. C. Lima, David R. Jacobs, Daniel Duprez, Lyndia Brumback, Kent D. Taylor, Peter Durda, W. Craig Johnson, Elaine Cornell, Xiuqing Guo, Yongmei Liu, Russell P. Tracy, Thomas W. Blackwell, George Papanicolaou, Gary F. Mitchell, Stephen S. Rich, Jerome I. Rotter, David J. Van Den Berg, Julio A. Chirinos, Timothy M. Hughes, Francine E. Garrett-Bakelman, Ani Manichaikul
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Despite the prognostic value of arterial stiffness (AS) and pulsatile hemodynamics (PH) for cardiovascular morbidity and mortality, epigenetic modifications that contribute to AS/PH remain unknown. To gain a better understanding of the link
Externí odkaz:
https://doaj.org/article/2566eec7931e4736bf4aa961b170b4a1
Autor:
Mohammad R Ostovaneh, Timothy M Hughes, Colin O Wu, Robyn L McClelland, Ramon Casanova, David A Bluemke, Russell P Tracy, Steven Shea, Susan R Heckbert, João A C Lima, Bharath Ambale-Venkatesh
Publikováno v:
PLoS ONE, Vol 19, Iss 4, p e0298952 (2024)
BackgroundOur understanding of the specific aspects of vascular contributions to dementia remains unclear.ObjectivesWe aim to identify the correlates of incident dementia in a multi-ethnic cardiovascular cohort.MethodsA total of 6806 participants wit
Externí odkaz:
https://doaj.org/article/d84c796ab626470dbd8440501e77629e
Autor:
Taibo Li, Nicole Ferraro, Benjamin J. Strober, Francois Aguet, Silva Kasela, Marios Arvanitis, Bohan Ni, Laurens Wiel, Elliot Hershberg, Kristin Ardlie, Dan E. Arking, Rebecca L. Beer, Jennifer Brody, Thomas W. Blackwell, Clary Clish, Stacey Gabriel, Robert Gerszten, Xiuqing Guo, Namrata Gupta, W. Craig Johnson, Tuuli Lappalainen, Henry J. Lin, Yongmei Liu, Deborah A. Nickerson, George Papanicolaou, Jonathan K. Pritchard, Pankaj Qasba, Ali Shojaie, Josh Smith, Nona Sotoodehnia, Kent D. Taylor, Russell P. Tracy, David Van Den Berg, Matthew T. Wheeler, Stephen S. Rich, Jerome I. Rotter, Alexis Battle, Stephen B. Montgomery
Publikováno v:
Cell Genomics, Vol 3, Iss 10, Pp 100401- (2023)
Summary: Each human genome has tens of thousands of rare genetic variants; however, identifying impactful rare variants remains a major challenge. We demonstrate how use of personal multi-omics can enable identification of impactful rare variants by
Externí odkaz:
https://doaj.org/article/d2548cee9ef64b4fa282cb83949a4d84
Autor:
Kristina L. Buschur, Craig Riley, Aabida Saferali, Peter Castaldi, Grace Zhang, Francois Aguet, Kristin G. Ardlie, Peter Durda, W. Craig Johnson, Silva Kasela, Yongmei Liu, Ani Manichaikul, Stephen S. Rich, Jerome I. Rotter, Josh Smith, Kent D. Taylor, Russell P. Tracy, Tuuli Lappalainen, R. Graham Barr, Frank Sciurba, Craig P. Hersh, Panayiotis V. Benos
Publikováno v:
Respiratory Research, Vol 24, Iss 1, Pp 1-12 (2023)
Abstract Background Chronic obstructive pulmonary disease (COPD) varies significantly in symptomatic and physiologic presentation. Identifying disease subtypes from molecular data, collected from easily accessible blood samples, can help stratify pat
Externí odkaz:
https://doaj.org/article/2432ac0f1e9a4ee08f8823576baf8705
Autor:
Arjun Sinha, Colleen M. Sitlani, Margaret F. Doyle, Alison E. Fohner, Petra Buzkova, James S. Floyd, Sally A. Huber, Nels C. Olson, Joyce N. Njoroge, Jorge R. Kizer, Joseph A. Delaney, Sanjiv S. Shah, Russell P. Tracy, Bruce Psaty, Matthew Feinstein
Publikováno v:
ESC Heart Failure, Vol 9, Iss 6, Pp 4177-4188 (2022)
Abstract Aims Circulating inflammatory markers are associated with incident heart failure (HF), but prospective data on associations of immune cell subsets with incident HF are lacking. We determined the associations of immune cell subsets with incid
Externí odkaz:
https://doaj.org/article/cd5a7593a71e467a9aaa6a00d054f8db
Autor:
Marsha M. Wheeler, Adrienne M. Stilp, Shuquan Rao, Bjarni V. Halldórsson, Doruk Beyter, Jia Wen, Anna V. Mihkaylova, Caitlin P. McHugh, John Lane, Min-Zhi Jiang, Laura M. Raffield, Goo Jun, Fritz J. Sedlazeck, Ginger Metcalf, Yao Yao, Joshua B. Bis, Nathalie Chami, Paul S. de Vries, Pinkal Desai, James S. Floyd, Yan Gao, Kai Kammers, Wonji Kim, Jee-Young Moon, Aakrosh Ratan, Lisa R. Yanek, Laura Almasy, Lewis C. Becker, John Blangero, Michael H. Cho, Joanne E. Curran, Myriam Fornage, Robert C. Kaplan, Joshua P. Lewis, Ruth J. F. Loos, Braxton D. Mitchell, Alanna C. Morrison, Michael Preuss, Bruce M. Psaty, Stephen S. Rich, Jerome I. Rotter, Hua Tang, Russell P. Tracy, Eric Boerwinkle, Goncalo R. Abecasis, Thomas W. Blackwell, Albert V. Smith, Andrew D. Johnson, Rasika A. Mathias, Deborah A. Nickerson, Matthew P. Conomos, Yun Li, Unnur Þorsteinsdóttir, Magnús K. Magnússon, Kari Stefansson, Nathan D. Pankratz, Daniel E. Bauer, Paul L. Auer, Alex P. Reiner
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Most genetic association studies have been done on single nucleotide polymorphisms and small indels, while other types of variants have been less studied. Here, the authors use whole genome sequencing in a diverse population to identify and provide e
Externí odkaz:
https://doaj.org/article/a133b13c75514301b2ec8c00097b28db