Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Russell P, Sawyer"'
Autor:
Sarah J. Doran, Russell P. Sawyer
Publikováno v:
Frontiers in Neuroscience, Vol 18 (2024)
Alzheimer’s disease (AD) affects over 6 million people over the age of 65. The advent of new anti-amyloid monoclonal antibodies as treatment for early Alzheimer’s disease these immunotherapeutics may slow disease progression but also pose signifi
Externí odkaz:
https://doaj.org/article/75c8721fa44d4629954f92f6f2613739
Autor:
Russell P. Sawyer, Bradford B. Worrall, Virginia J. Howard, Michael G. Crowe, George Howard, Hyacinth I. Hyacinth
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 17 (2023)
Background Non‐Hispanic Black adults have a higher proportion of vascular cognitive impairment and Alzheimer's disease and related dementias compared with non‐Hispanic White adults that may be due to differences in the burden of cerebral small ve
Externí odkaz:
https://doaj.org/article/e3398cc6dda24a56b973bb371ec1ed3f
Autor:
Emerlee Andersen, Bryce Casteigne, William Daniel Chapman, Andrew Creed, Forrest Foster, Allison Lapins, Rhonna Shatz, Russell P. Sawyer
Publikováno v:
Biomarkers in Neuropsychiatry, Vol 5, Iss , Pp 100041- (2021)
In this review article we examine the various types of diagnostic biomarkers which are used in the early detection of Alzheimer’s disease. This review summerizes the A/T/N classification system for Alzheimer’s biomarkers and its use in the biomar
Externí odkaz:
https://doaj.org/article/e7fc6b193b734a238dd33e6bf7f3734f
Autor:
Russell P. Sawyer, Sirjana Pun, Kristine A. Karkoska, Cherita A. Clendinen, Michael R. DeBaun, Ephraim Gutmark, Riccardo Barrile, Hyacinth I. Hyacinth
Publikováno v:
Brain Sciences, Vol 12, Iss 10, p 1402 (2022)
The main objective of this study was to demonstrate that computational fluid dynamics (CFD) modeling can be used to study the contribution of covert and overt vascular architecture to the risk for cerebrovascular disease in sickle cell disease (SCD)
Externí odkaz:
https://doaj.org/article/979b77bc4c614b8383fcb69cef045022
Autor:
Luke W. Bonham, Ethan G. Geier, Daniel W. Sirkis, Josiah K. Leong, Eliana Marisa Ramos, Qing Wang, Anna Karydas, Suzee E. Lee, Virginia E. Sturm, Russell P. Sawyer, Adit Friedberg, Justin K. Ichida, Aaron D. Gitler, Leo Sugrue, Michael Cordingley, Walter Bee, Eckard Weber, Joel H. Kramer, Katherine P. Rankin, Howard J. Rosen, Adam L. Boxer, William W. Seeley, John Ravits, Bruce L. Miller, Jennifer S. Yokoyama
Publikováno v:
The Journal of Neuroscience. 43:333-345
Hexanucleotide repeat expansion (HRE) withinC9orf72is the most common genetic cause of frontotemporal dementia (FTD). Thalamic atrophy occurs in both sporadic and familial FTD but is thought to distinctly affect HRE carriers. Separately, emerging evi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5cfdbe4480f987d12b252f86e4c33446
https://doi.org/10.1523/jneurosci.1448-22.2022
https://doi.org/10.1523/jneurosci.1448-22.2022
Autor:
Luke W. Bonham, Ethan G. Geier, Daniel W. Sirkis, Josiah K. Leong, Eliana Marisa Ramos, Qing Wang, Anna Karydas, Suzee E. Lee, Virginia E. Sturm, Russell P. Sawyer, Adit Friedberg, Justin K. Ichida, Aaron D. Gitler, Leo Sugrue, Michael Cordingley, Walter Bee, Eckard Weber, Joel Kramer, Katherine P. Rankin, Howard J. Rosen, Adam L. Boxer, William W. Seeley, John Ravits, Bruce L. Miller, Jennifer S. Yokoyama
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience, vol 43, iss 2
Hexanucleotide repeat expansion (HRE) within C9orf72 is the most common genetic cause of frontotemporal dementia (FTD). Thalamic atrophy occurs in both sporadic and familial FTD but is thought to distinctly affect HRE carriers. Separately, emerging e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26db290663368430e8978af72589564d
https://escholarship.org/uc/item/7jr289cm
https://escholarship.org/uc/item/7jr289cm
Autor:
Jonathan Pounders, Emily J. Hill, Destiny Hooper, Xiang Zhang, Jacek Biesiada, Damaris Kuhnell, Hannah L. Greenland, Leyla Esfandiari, Emerlee Timmerman, Forrest Foster, Chenran Wang, Kyle B. Walsh, Rhonna Shatz, Daniel Woo, Mario Medvedovic, Scott Langevin, Russell P. Sawyer
Publikováno v:
Medicine. 101(40)
MicroRNAs (miRNAs) are small non-coding RNA that are powerful regulators of gene expression and can affect the expression of hundreds of genes. miRNAs can be packed in small extracellular vesicles (SEV) and released into the extracellular space by ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46e1f574e7108be965f7798715fca5a3
https://pubmed.ncbi.nlm.nih.gov/36221381
https://pubmed.ncbi.nlm.nih.gov/36221381
Autor:
Russell P. Sawyer, Stacie L. Demel, Mary E. Comeau, Miranda Marion, Jonathan Rosand, Carl D. Langefeld, Daniel Woo
Publikováno v:
Medicine. 101(39)
Apolipoprotein E alleles have been associated with both Alzheimer's disease (AD) and intracerebral hemorrhage (ICH). In addition, ICH is associated with a markedly high risk of subsequent dementia compared to other subtypes of stroke. We sought to ev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4173fd8bbb7c3f167c0b393fd3fe0d0f
https://pubmed.ncbi.nlm.nih.gov/36181103
https://pubmed.ncbi.nlm.nih.gov/36181103
Autor:
Luke W, Bonham, Ethan G, Geier, Daniel W, Sirkis, Josiah K, Leong, Eliana Marisa, Ramos, Qing, Wang, Anna, Karydas, Suzee E, Lee, Virginia E, Sturm, Russell P, Sawyer, Adit, Friedberg, Justin K, Ichida, Aaron D, Gitler, Leo, Sugrue, Michael, Cordingley, Walter, Bee, Eckard, Weber, Joel, Kramer, Katherine P, Rankin, Howard J, Rosen, Adam L, Boxer, William W, Seeley, John, Ravits, Bruce L, Miller, Jennifer S, Yokoyama
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience.
Hexanucleotide repeat expansion (HRE) within
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e2fe554bda70919f61cdfb9daa1ac741
https://pubmed.ncbi.nlm.nih.gov/36446586
https://pubmed.ncbi.nlm.nih.gov/36446586
Publikováno v:
Stroke. 52:603-610
Background and Purpose: In intracerebral hemorrhage (ICH), preexisting cognitive impairment has been identified as a risk factor for increased mortality and morbidity. However, previous studies examined predominantly White populations; therefore, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e94733d0c01bab92238b06c33f3b619
https://doi.org/10.1161/strokeaha.120.030084
https://doi.org/10.1161/strokeaha.120.030084