Zobrazeno 1 - 10
of 124
pro vyhledávání: '"Russell L. Moore"'
Autor:
Derek K. Zachman, Adam J. Chicco, Sylvia A. McCune, Robert C. Murphy, Russell L. Moore, Genevieve C. Sparagna
Publikováno v:
Journal of Lipid Research, Vol 51, Iss 3, Pp 525-534 (2010)
Cardiolipin (CL) is an essential phospholipid component of the inner mitochondrial membrane. In the mammalian heart, the functional form of CL is tetralinoleoyl CL [(18:2)4CL]. A decrease in (18:2)4CL content, which is believed to negatively impact m
Externí odkaz:
https://doaj.org/article/f66d6757f9384afab827c0e878fdddec
Autor:
Harjot K. Saini-Chohan, Michael G. Holmes, Adam J. Chicco, William A. Taylor, Russell L. Moore, Sylvia A. McCune, Diane L. Hickson-Bick, Grant M. Hatch, Genevieve C. Sparagna
Publikováno v:
Journal of Lipid Research, Vol 50, Iss 8, Pp 1600-1608 (2009)
Cardiolipin (CL) is responsible for modulation of activities of various enzymes involved in oxidative phosphorylation. Although energy production decreases in heart failure (HF), regulation of cardiolipin during HF development is unknown. Enzymes inv
Externí odkaz:
https://doaj.org/article/7cc5d38a1ac741f3a2a59f388296add9
Autor:
Genevieve C. Sparagna, Adam J. Chicco, Robert C. Murphy, Michael R. Bristow, Christopher A. Johnson, Meredith L. Rees, Melissa L. Maxey, Sylvia A. McCune, Russell L. Moore
Publikováno v:
Journal of Lipid Research, Vol 48, Iss 7, Pp 1559-1570 (2007)
The mitochondrial phospholipid cardiolipin is required for optimal mitochondrial respiration. In this study, cardiolipin molecular species and cytochrome oxidase (COx) activity were studied in interfibrillar (IF) and subsarcolemmal (SSL) cardiac mito
Externí odkaz:
https://doaj.org/article/bfea82e13bcd4da2aa957d45b6be93a4
Autor:
Genevieve C. Sparagna, Chris A. Johnson, Sylvia A. McCune, Russell L. Moore, Robert C. Murphy
Publikováno v:
Journal of Lipid Research, Vol 46, Iss 6, Pp 1196-1204 (2005)
Electrospray ionization mass spectrometry has previously been used to probe qualitative changes in the phospholipid cardiolipin (CL), but it has rarely been used in a quantitative manner. We assessed changes in the amount of individual molecular spec
Externí odkaz:
https://doaj.org/article/57475b9cfab34b109a8cc0d2ce579681
Autor:
Catherine H. Le, Robert C. Murphy, Christopher M. Mulligan, Gerrit J. Bouma, Melissa A. Routh, Michael R. Bristow, Russell L. Moore, Genevieve C. Sparagna, Kimberly M. Jeckel, Sylvia A. McCune, Simona Zarini, Adam J. Chicco, Melinda A. Frye, Joshua M. Lynch
Publikováno v:
Circulation: Heart Failure. 7:172-183
Background— Remodeling of myocardial phospholipids has been reported in various forms of heart failure for decades, but the mechanism and pathophysiological relevance of this phenomenon have remained unclear. We examined the hypothesis that δ-6 de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0846efe3f99ef5b51b974a97576e724
https://doi.org/10.1161/circheartfailure.113.000744
https://doi.org/10.1161/circheartfailure.113.000744
Publikováno v:
Journal of Applied Physiology. 111:905-915
The ability of exercise to protect the heart against ischemia-reperfusion (I/R) injury is well known in both human epidemiological studies and experimental animal models. In this review article, we describe what is currently known about the ability o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4975e8cdca224fbe38bcb9803536b53f
https://doi.org/10.1152/japplphysiol.00004.2011
https://doi.org/10.1152/japplphysiol.00004.2011
Autor:
Lisa A. Lesniewski, Douglas R. Seals, Rachel A. Gioscia, Andrew G. Edwards, Russell L. Moore, Anthony J. Donato
Publikováno v:
Mechanisms of Ageing and Development. 131:739-742
Short-term caloric restriction (CR) protects the young myocardium against ischemia/reperfusion (I/R) injury through a mechanism involving AMP-activated protein kinase (AMPK). Here we ask whether a life-long CR intervention can extend this protection
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63744b653ef4b3e5de095703772c1253
https://doi.org/10.1016/j.mad.2010.09.007
https://doi.org/10.1016/j.mad.2010.09.007
Autor:
R. Dale Brown, Wilson S. Colucci, John S. Walker, Mark Y. Jeong, Russell L. Moore, Carlin S. Long, Charles Vinson
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 298:H1719-H1726
Using neonatal rat ventricular myocytes, we previously reported that the expression of a dominant negative form of the c-Fos proto-oncogene (AFos) inhibited activator protein 1 activity and blocked the induction of the pathological gene profile stimu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b879b7ce4a4337327c9c0e46fada72ff
https://doi.org/10.1152/ajpheart.00937.2009
https://doi.org/10.1152/ajpheart.00937.2009
Autor:
Robert C. Murphy, Sylvia A. McCune, Adam J. Chicco, Derek K. Zachman, Genevieve C. Sparagna, Russell L. Moore
Publikováno v:
Journal of Lipid Research, Vol 51, Iss 3, Pp 525-534 (2010)
Cardiolipin (CL) is an essential phospholipid component of the inner mitochondrial membrane. In the mammalian heart, the functional form of CL is tetralinoleoyl CL [(18:2)(4)CL]. A decrease in (18:2)(4)CL content, which is believed to negatively impa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::355aa35ede723b5476ef304a38cede43
http://www.sciencedirect.com/science/article/pii/S0022227520305101
http://www.sciencedirect.com/science/article/pii/S0022227520305101
Autor:
Joshua M. Lynch, Rachel A. Gioscia, Jason C. Browder, Russell L. Moore, Meredith L. Rees, Andrew G. Edwards, Derek K. Zachman, Adam J. Chicco
Publikováno v:
The Journal of Physiology. 587:5723-5737
The female myocardium, relative to that of the male, exhibits sustained resistance to ischaemic tissue injury, a phenomenon termed sex-specific cardioprotection (SSC). SSC is dependent upon the sarcolemmal KATP channel (sarcKATP), and protein kinase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a8869463d5b544a3ded57ef2df4f3d94
https://doi.org/10.1113/jphysiol.2009.181040
https://doi.org/10.1113/jphysiol.2009.181040