Zobrazeno 1 - 10
of 130
pro vyhledávání: '"Russell K Pachynski"'
Autor:
Renee N Donahue, Jeffrey Schlom, James L Gulley, Mario Sznol, Andreas Schroeder, Julius Strauss, Luc Dirix, Michele Maio, Frank Beier, Alain Ravaud, Jean-Laurent Deville, Marco Maruzzo, XiaoZhe Wang, Yulia Vugmeyster, Sarah Chennoufi, Yo-Ting Tsai, Russell K Pachynski, Theodore S Gourdin, Joerg Seebeck
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 5 (2023)
Background In preclinical studies, combining M9241 (a novel immunocytokine containing interleukin (IL)-12 heterodimers) with avelumab (anti-programmed death ligand 1 antibody) resulted in additive or synergistic antitumor effects. We report dose-esca
Externí odkaz:
https://doaj.org/article/b7193fb23a874fb9822f7bc391a3e7f9
Autor:
Jun Li, Stefanie Zschäbitz, Daniel P Petrylak, Margitta Retz, Prabhu Bhagavatheeswaran, Marc-Oliver Grimm, Jose Perez-Gracia, Gwenaelle Gravis, Karim Fizazi, Jeffrey C Goh, Mauricio Burotto, Daniel Castellano, Fred Saad, Andrew J Armstrong, HAKIM MAHAMMEDI, Russell K Pachynski, Louis Lacombe, Diogo Assed Bastos, Steven L McCune, Juan Carlos Vázquez Limón, Edmond M Kwan, Aude Fléchon, David R Shaffer, Neha P Amin, Keziban Ünsal-Kaçmaz, Xuya Wang, Andrea Loehr
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 8 (2022)
Background CheckMate 9KD (NCT03338790) is a non-randomized, multicohort, phase 2 trial of nivolumab plus other anticancer treatments for metastatic castration-resistant prostate cancer (mCRPC). We report results from cohorts A1 and A2 of CheckMate 9K
Externí odkaz:
https://doaj.org/article/47bed5baf90f4a54860bcc0aa14ca352
Autor:
Holden T Maecker, Lawrence Fong, Leonard D’Amico, Martin Cheever, Leonard Appleman, Steven P Fling, Nirasha Ramchurren, Russell Szmulewitz, Omer Kucuk, Paul Monk, Caroline Duault, Russell K Pachynski, Lauren Harshman, Rhonda L Bitting, Frederick Millard, John D Seigne, Bruce Hess, Andreanne Lacroix, Judith C Kaiser, Michel Morre, Anne Grégoire, Evan Y Yu
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 8 (2021)
Externí odkaz:
https://doaj.org/article/54ac985393a84044a1fcf9109a088cab
Publikováno v:
Journal of Bone Oncology, Vol 45, Iss , Pp 100589- (2024)
Externí odkaz:
https://doaj.org/article/38bff93b2918428d8f52e0dfca18c464
Autor:
Yixuan Wang, Jeremiah J. Morrissey, Prashant Gupta, Pradeep Chauhan, Russell K. Pachynski, Peter K. Harris, Aadel Chaudhuri, Srikanth Singamaneni
Publikováno v:
ACS Applied Materials & Interfaces. 15:18598-18607
Autor:
Yige Wu, Nadezhda V. Terekhanova, Wagma Caravan, Nataly Naser Al Deen, Preet Lal, Siqi Chen, Chia-Kuei Mo, Song Cao, Yize Li, Alla Karpova, Ruiyang Liu, Yanyan Zhao, Andrew Shinkle, Ilya Strunilin, Cody Weimholt, Kazuhito Sato, Lijun Yao, Mamatha Serasanambati, Xiaolu Yang, Matthew Wyczalkowski, Houxiang Zhu, Daniel Cui Zhou, Reyka G. Jayasinghe, Daniel Mendez, Michael C. Wendl, David Clark, Chelsea Newton, Yijun Ruan, Melissa A. Reimers, Russell K. Pachynski, Chris Kinsinger, Scott Jewell, Daniel W. Chan, Hui Zhang, Aadel A. Chaudhuri, Milan G. Chheda, Benjamin D. Humphreys, Mehdi Mesri, Henry Rodriguez, James J. Hsieh, Li Ding, Feng Chen
Publikováno v:
Nature Communications. 14
Autor:
James J. Hsieh, Ravshan Ataullakhanov, Gerald L. Andriole, Maria Tsiper, Krystle Nomie, Olga Gancharova, Maria Bruttan, Alexander Bagaev, Joseph E. Ippolito, Joseph Gaut, Dengfeng Cao, Qiong Zou, Yang Lyu, Viktor Svekolkin, Ilia Galkin, Ekaterina Postovalova, Akshaya Ramachandran, Nikita Kotlov, Natalia Miheecheva, Eric H. Kim, Russell K. Pachynski
Supplementary Figure S2. The mpMRI-visible PCa tumors show marked differences between the malignant and non-malignant compartments. A, Box plots showing WD per mpMRI-invisible and -visible PCa tumors. P-values were calculated with the Mann-Whitney U
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e43ab0e5aad9a374603be7bd24fa2b9
https://doi.org/10.1158/1078-0432.22479602
https://doi.org/10.1158/1078-0432.22479602
Autor:
Christopher J. Harvey, Elizabeth Trehu, Richard Murray, Haley Laken, Johan Baeck, Weidong Zhang, Judith Jimenez, Ali Sepahi, Karen Brown, Rachel McComb, Courtney Hart, Daniel Felitsky, Martin Fan, Heather Cohen, Xiaoying Xiao, Ellen Hooper, Lara McGrath, Yasmin Hashambhoy-Ramsay, Amanda Hanson, Haeseong Park, Mariela Blum Murphy, Kyriakos P. Papadopoulos, Tanguy Y. Seiwert, Osama E. Rahma, Scott S. Tykodi, Howard A. Burris, Geoffrey T. Gibney, Shivaani Kummar, Patricia LoRusso, Russell K. Pachynski, Gerald S. Falchook, Margaret K. Callahan, Justin F. Gainor, Timothy A. Yap
Supplementary Data from First-in-Human Phase I/II ICONIC Trial of the ICOS Agonist Vopratelimab Alone and with Nivolumab: ICOS-High CD4 T-Cell Populations and Predictors of Response
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04ebbd64661cbba269a9c3230a5032f2
https://doi.org/10.1158/1078-0432.22487579.v1
https://doi.org/10.1158/1078-0432.22487579.v1
Supplementary Figure 8. Knockdown of PTEN and PD-L1 Expression in DU145 Cells. A. Western blot analysis for PTEN expression after transfection with siRNA. Loading control bands are probed with anti-GAPDH antibody on the same blot. DU145 cells were tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b3d4988fcf4bb96ac9cd73f08a1e4be
https://doi.org/10.1158/1078-0432.22474842
https://doi.org/10.1158/1078-0432.22474842
Supplementary Figure 3. Chemerin incubation has no significant effect on tumor cell apoptosis. DU145 tumor cells were treated with PBS or 6nM chemerin concentration for 48h. Following initial incubation, cells were continued to be treated for 24h wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cf87909936fda3fc26e03585ffa00fa
https://doi.org/10.1158/1078-0432.22474863.v1
https://doi.org/10.1158/1078-0432.22474863.v1