Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Russell J. Juno"'
Autor:
Christopher R. Erwin, Marcus D. Jarboe, Brad W. Warner, Nicole P. Bernal, Yufang Zhang, Russell J. Juno, Andrew W. Knott
Publikováno v:
Surgery. 136:121-126
Background Adaptation after massive smallbowel resection (SBR) is associated with increased cell turnover, increased rates of enterocyte proliferation, and apoptosis. Epidermal growth factor receptor (EGFR) inhibition attenuates adaptation and increa
Autor:
Russell J. Juno, Sherri A. Profitt, Marcus D. Jarboe, Brad W. Warner, Andrew W. Knott, Christopher R. Erwin
Publikováno v:
Surgery. 134:582-589
Background After massive small bowel resection (SBR), the remnant bowel adapts by increasing enterocyte proliferation and apoptosis. The purpose of this study was to investigate the relevance of luminal bacteria on postresection intestinal cell turno
Autor:
Sherri A. Profitt, Christopher R. Erwin, Janice C Thoerner, Andrew W. Knott, Yufang Zhang, Marcus D. Jarboe, Russell J. Juno, Brad W. Warner
Publikováno v:
Journal of Pediatric Surgery. 38:875-880
Background After massive small bowel resection (SBR), enterocyte apoptosis is elevated and inversely correlates with epidermal growth factor receptor (EGFR) signaling. The purpose of the current study was to determine whether EGFR manipulation affect
Publikováno v:
Journal of Pediatric Surgery. 38:868-874
Background/purpose After small bowel resection (SBR), serum induces proliferation in rat intestinal epithelial cells (RIEC-6). This study was designed to elucidate the effects of postoperative time interval, site, and magnitude of SBR on RIEC-6 proli
Publikováno v:
Seminars in Pediatric Surgery. 12:132-139
The maintenance of long-term venous access is critical to the livelihood of children in a variety of clinical situations, especially those who are dependent on parenteral nutrition. Whereas the traditional routes of either peripheral or central venou
Publikováno v:
Journal of Pediatric Surgery. 38:440-445
Background/Purpose: Epidermal growth factor (EGF) and its receptor (EGFR) are key components in the genesis of adaptation after small bowel resection (SBR). Within intestinal homogenates, EGFR expression is increased after SBR; however, the exact cel
Autor:
Russell J. Juno, Brad W. Warner, Christopher R. Erwin, David P. O'Brien, Andrew W. Knott, Jodi L. Williams
Publikováno v:
Surgery. 132:377-383
Background. In vivo, intestinal adaptation after massive small bowel resection (SBR) requires a functional epidermal growth factor (EGF) receptor (EGFR). In vitro studies have shown that serum from mice after SBR induces rat intestinal epithelial cel
Autor:
Sherri A. Profitt, Nicole P. Bernal, Christopher R. Erwin, Brad W. Warner, Marcus D. Jarboe, Russell J. Juno, Wolfgang Stehr
Publikováno v:
Journal of pediatric surgery. 40(1)
Background/Purpose Intestinal adaptation is a compensatory response to massive small bowel loss in which there are increased numbers of absorptive enterocytes. However, the generation of secretory epithelial cell subtypes in this process has not been
Autor:
Andrew W. Knott, Russell J. Juno, Brad W. Warner, Sherri A. Profitt, Marcus D. Jarboe, Christopher R. Erwin, Eric P. Smith, James A. Fagin
Publikováno v:
American journal of physiology. Gastrointestinal and liver physiology. 287(3)
Prior studies of intestinal adaptation after massive small bowel resection (SBR) have focused on growth factors and their effects on amplification of the gut mucosa. Because adaptive changes have also been described in intestinal smooth muscle, we so
Autor:
Russell J. Juno, David P. O'Brien, Andrew W. Knott, Jodi L. Williams, Brad W. Warner, Yufang Zhang, Christopher R. Erwin
Publikováno v:
American journal of physiology. Gastrointestinal and liver physiology. 285(2)
Intestinal adaptation following small bowel resection (SBR) is associated with greater rates of enterocyte apoptosis by unknown mechanism(s). Because postresection adaptation is associated with increased translocation of luminal bacteria, we sought t