Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Russell J Dickson"'
Autor:
Russell J Dickson, Gregory B Gloor
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e37645 (2012)
The use of sequence alignments to understand protein families is ubiquitous in molecular biology. High quality alignments are difficult to build and protein alignment remains one of the largest open problems in computational biology. Misalignments ca
Externí odkaz:
https://doaj.org/article/22f81d08a4ae4a2aa2de66b6c6438b95
Autor:
Gregory B Gloor, Ruben Hummelen, Jean M Macklaim, Russell J Dickson, Andrew D Fernandes, Roderick MacPhee, Gregor Reid
Publikováno v:
PLoS ONE, Vol 5, Iss 10, p e15406 (2010)
We developed a low-cost, high-throughput microbiome profiling method that uses combinatorial sequence tags attached to PCR primers that amplify the rRNA V6 region. Amplified PCR products are sequenced using an Illumina paired-end protocol to generate
Externí odkaz:
https://doaj.org/article/a4021e9d62ef49079a966cadeb184f05
Autor:
Ruben Hummelen, Andrew D Fernandes, Jean M Macklaim, Russell J Dickson, John Changalucha, Gregory B Gloor, Gregor Reid
Publikováno v:
PLoS ONE, Vol 5, Iss 8, p e12078 (2010)
Women living with HIV and co-infected with bacterial vaginosis (BV) are at higher risk for transmitting HIV to a partner or newborn. It is poorly understood which bacterial communities constitute BV or the normal vaginal microbiota among this populat
Externí odkaz:
https://doaj.org/article/a0c19bbd67384a70a9cb4ff5620307e7
Publikováno v:
PLoS ONE, Vol 5, Iss 6, p e11082 (2010)
BACKGROUND: There is currently no way to verify the quality of a multiple sequence alignment that is independent of the assumptions used to build it. Sequence alignments are typically evaluated by a number of established criteria: sequence conservati
Externí odkaz:
https://doaj.org/article/95f97a3c895c47f5b895f7a3de6ea6d6
Autor:
Bethany L. MacLeod, Laura M. Snell, Russell J. Dickson, Kebria Hezaveh, Cynthia J. Guidos, Mengdi Guo, Heidi Elsaesser, W. Xu, Tracy L. McGaha, David G. Brooks, Akash Kothari
Publikováno v:
The Journal of Experimental Medicine
Macleod et al. uncover how chronic viral infection modulates gastrointestinal immune and microbial composition to foster persistence and long-term disease susceptibilities. The authors also identify the central role of regulatory T cells to maintain
Autor:
Ramy Gadalla, Babak Noamani, Bethany L. MacLeod, Russell J. Dickson, Mengdi Guo, Wenxi Xu, Sabelo Lukhele, Heidi J. Elsaesser, Albiruni R. Abdul Razak, Naoto Hirano, Tracy L. McGaha, Ben Wang, Marcus Butler, Cynthia J. Guidos, Pam S. Ohashi, Lillian L. Siu, David G. Brooks
Publikováno v:
Frontiers in Oncology
Frontiers in Oncology, Vol 9 (2019)
Frontiers in Oncology, Vol 9 (2019)
Flow cytometry is a widely applied approach for exploratory immune profiling and biomarker discovery in cancer and other diseases. However, flow cytometry is limited by the number of parameters that can be simultaneously analyzed, severely restrictin
Autor:
David G. Brooks, Kebria Hezaveh, Bethany L. MacLeod, Marc A. Gavin, Jaclyn C. Law, Ivan Osokine, Laura M. Snell, Russell J. Dickson, Heidi Elsaesser, Tracy L. McGaha, Cynthia J. Guidos
Publikováno v:
Immunity
CD8(+) T cell exhaustion impedes control of chronic viral infection; yet how new T cell responses are mounted during chronic infection is unclear. Unlike T cells primed at the onset of infection that rapidly differentiate into effectors and exhaust,
Autor:
Stephanie M. F. Thibert, Russell J. Dickson, Thomas A McMurrough, Gregory B. Gloor, David R. Edgell
Publikováno v:
Proceedings of the National Academy of Sciences. 111
The active sites of enzymes consist of residues necessary for catalysis and structurally important noncatalytic residues that together maintain the architecture and function of the active site. Examples of evolutionary interactions between catalytic
Autor:
Russell J, Dickson, Gregory B, Gloor
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1123
Positions in a protein are thought to coevolve to maintain important structural and functional interactions over evolutionary time. The detection of putative coevolving positions can provide important new insights into a protein family in the same wa
Autor:
Russell J. Dickson, Gregory B. Gloor
Publikováno v:
Methods in Molecular Biology ISBN: 9781627039673
Positions in a protein are thought to coevolve to maintain important structural and functional interactions over evolutionary time. The detection of putative coevolving positions can provide important new insights into a protein family in the same wa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::92e701f0c7d075add8c147a189dc464e
https://doi.org/10.1007/978-1-62703-968-0_15
https://doi.org/10.1007/978-1-62703-968-0_15