Zobrazeno 1 - 10
of 210
pro vyhledávání: '"Russell J Cox"'
Autor:
Scott A Griffiths, Russell J Cox, Elysa J R Overdijk, Carl H Mesarich, Benedetta Saccomanno, Colin M Lazarus, Pierre J G M de Wit, Jérôme Collemare
Publikováno v:
PLoS ONE, Vol 13, Iss 12, p e0209600 (2018)
Pigments and phytotoxins are crucial for the survival and spread of plant pathogenic fungi. The genome of the tomato biotrophic fungal pathogen Cladosporium fulvum contains a predicted gene cluster (CfPKS1, CfPRF1, CfRDT1 and CfTSF1) that is syntenic
Externí odkaz:
https://doaj.org/article/43c3e51e491d453d8dd7b33a8274309e
Autor:
Jérôme Collemare, Scott Griffiths, Yuichiro Iida, Mansoor Karimi Jashni, Evy Battaglia, Russell J Cox, Pierre J G M de Wit
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e85877 (2014)
Cladosporium fulvum is a biotrophic fungal pathogen that causes leaf mould of tomato. Analysis of its genome suggested a high potential for production of secondary metabolites (SM), which might be harmful to plants and animals. Here, we have analysed
Externí odkaz:
https://doaj.org/article/48ff6b5d693a4f878c3074fc20f46fa1
A natural plasmid uniquely encodes two biosynthetic pathways creating a potent anti-MRSA antibiotic.
Autor:
Daisuke Fukuda, Anthony S Haines, Zhongshu Song, Annabel C Murphy, Joanne Hothersall, Elton R Stephens, Rachel Gurney, Russell J Cox, John Crosby, Christine L Willis, Thomas J Simpson, Christopher M Thomas
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e18031 (2011)
Understanding how complex antibiotics are synthesised by their producer bacteria is essential for creation of new families of bioactive compounds. Thiomarinols, produced by marine bacteria belonging to the genus Pseudoalteromonas, are hybrids of two
Externí odkaz:
https://doaj.org/article/f65d8ef4119a44789cb398feeee148db
Autor:
Sabrina Collin, Russell J. Cox, Cédric Paris, Christophe Jacob, Benjamin Chagot, Kira J. Weissman, Arnaud Gruez
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Biosynthesis of complex polyketides by polyketide synthases often relies on trans-acting enzymes to modify the intermediates. Here, the authors elucidate how β-methylation enzymes identify their substrates. The recognition is imperfect, resulting in
Externí odkaz:
https://doaj.org/article/277ce5ce2daf472f98faa92625d7d1ad
Publikováno v:
Frontiers in Chemistry, Vol 10 (2022)
A chemical investigation on the kiwi endophytic fungus Bipolaris sp. Resulted in the isolation of eight new terpenoids (1–8) and five known analogues (9–13). Compounds 1–5 are novel sativene sesquiterpenoids containing three additional skeletal
Externí odkaz:
https://doaj.org/article/d0cbd25397414449add275983c7f7935
Publikováno v:
Organic & Biomolecular Chemistry. 20:7278-7283
Antroxazole A is a novel chamigrane dimer featuring with a dihydrooxazole moiety from Antrodiella albocinnamomea. It inhibits LPS-induced proliferation of B lymphocyte cells with an IC50 value of 16.3 μM.
Autor:
Sabrina Collin, Russell J. Cox, Cédric Paris, Christophe Jacob, Benjamin Chagot, Kira J. Weissman, Arnaud Gruez
During biosynthesis by multi-modular trans-AT polyketide synthases, polyketide structural space can be expanded by conversion of initially-formed electrophilic β-ketones into β-alkyl groups. These multi-step transformations are catalysed by 3-hydro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af22406c9b03f3b4e316f5d67b2f4d63
https://doi.org/10.21203/rs.3.rs-2103032/v1
https://doi.org/10.21203/rs.3.rs-2103032/v1
Publikováno v:
European Journal of Organic Chemistry. 2021:5094-5103
Publikováno v:
Angewandte Chemie. 133:20470-20475
Autor:
Katherine Williams, Agnieszka J. Szwalbe, Kate M. J. de Mattos-Shipley, Andy M. Bailey, Russell J. Cox, Christine L. Willis
Publikováno v:
Natural Product Reports 40 (2023), Nr. 1
Natural Product Reports
Williams, K, Szwalbe, A J, de Mattos-Shipley, K M J, Bailey, A M, Cox, R & Willis, C L 2022, ' Maleidride biosynthesis – construction of dimeric anhydrides – more than just heads or tails ', Natural Product Reports, vol. 40, pp. 128-157 . https://doi.org/10.1039/D2NP00041E
Natural Product Reports
Williams, K, Szwalbe, A J, de Mattos-Shipley, K M J, Bailey, A M, Cox, R & Willis, C L 2022, ' Maleidride biosynthesis – construction of dimeric anhydrides – more than just heads or tails ', Natural Product Reports, vol. 40, pp. 128-157 . https://doi.org/10.1039/D2NP00041E
Covering: up to early 2022 Maleidrides are a family of polyketide-based dimeric natural products isolated from fungi. Many maleidrides possess significant bioactivities, making them attractive pharmaceutical or agrochemical lead compounds. Their unus