Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Russell G. Dushin"'
Autor:
Barbra J. Sasu, Javier Chaparro-Riggers, Pavel Strop, Arvind Rajpal, David Shelton, Jeffrey L. Wolf, Thomas G. Martin, Bernard Buetow, Ingrid Pardo, Michael Mirsky, Bora Han, Bing Kuang, Allison G. Chunyk, Kevin C. Lindquist, Yik Andy Yeung, Thomas J. Van Blarcom, Sherman M. Chin, Russell G. Dushin, Marjorie Bateman, Santiago Farias, Kathy Delaria, Wei Chen, Edward Pascua, Cris Kamperschroer, Laura Aschenbrenner, Tao Geng, Amy Chen, Yi Zhang, Tracy C. Kuo, Siler H. Panowski
BCMA bispecific is highly active in vivo.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::748b3e6c190c08ac317b01e7ce3f2069
https://doi.org/10.1158/1535-7163.22510278
https://doi.org/10.1158/1535-7163.22510278
Autor:
Barbra J. Sasu, Javier Chaparro-Riggers, Pavel Strop, Arvind Rajpal, David Shelton, Jeffrey L. Wolf, Thomas G. Martin, Bernard Buetow, Ingrid Pardo, Michael Mirsky, Bora Han, Bing Kuang, Allison G. Chunyk, Kevin C. Lindquist, Yik Andy Yeung, Thomas J. Van Blarcom, Sherman M. Chin, Russell G. Dushin, Marjorie Bateman, Santiago Farias, Kathy Delaria, Wei Chen, Edward Pascua, Cris Kamperschroer, Laura Aschenbrenner, Tao Geng, Amy Chen, Yi Zhang, Tracy C. Kuo, Siler H. Panowski
Tables show PK kinetics, plasma cell numbers, and patient data. Methods include all supplemental methods.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f21b0175c33170d2642c58ea1c4072b
https://doi.org/10.1158/1535-7163.22510263
https://doi.org/10.1158/1535-7163.22510263
Autor:
Barbra J. Sasu, Javier Chaparro-Riggers, Pavel Strop, Arvind Rajpal, David Shelton, Jeffrey L. Wolf, Thomas G. Martin, Bernard Buetow, Ingrid Pardo, Michael Mirsky, Bora Han, Bing Kuang, Allison G. Chunyk, Kevin C. Lindquist, Yik Andy Yeung, Thomas J. Van Blarcom, Sherman M. Chin, Russell G. Dushin, Marjorie Bateman, Santiago Farias, Kathy Delaria, Wei Chen, Edward Pascua, Cris Kamperschroer, Laura Aschenbrenner, Tao Geng, Amy Chen, Yi Zhang, Tracy C. Kuo, Siler H. Panowski
BCMA bispecific is activity in the presence of soluble BCMA and APRIL.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f73af5062730f6d9e5e6a1a18ddc6b3
https://doi.org/10.1158/1535-7163.22510281.v1
https://doi.org/10.1158/1535-7163.22510281.v1
Autor:
Barbra J. Sasu, Javier Chaparro-Riggers, Pavel Strop, Arvind Rajpal, David Shelton, Jeffrey L. Wolf, Thomas G. Martin, Bernard Buetow, Ingrid Pardo, Michael Mirsky, Bora Han, Bing Kuang, Allison G. Chunyk, Kevin C. Lindquist, Yik Andy Yeung, Thomas J. Van Blarcom, Sherman M. Chin, Russell G. Dushin, Marjorie Bateman, Santiago Farias, Kathy Delaria, Wei Chen, Edward Pascua, Cris Kamperschroer, Laura Aschenbrenner, Tao Geng, Amy Chen, Yi Zhang, Tracy C. Kuo, Siler H. Panowski
BCMA cleavable and non-cleavable ADCs are highly active against xenograft tumors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::897091b72e69dfafb1f3be2c32295fc1
https://doi.org/10.1158/1535-7163.22510275
https://doi.org/10.1158/1535-7163.22510275
Autor:
Barbra J. Sasu, Javier Chaparro-Riggers, Pavel Strop, Arvind Rajpal, David Shelton, Jeffrey L. Wolf, Thomas G. Martin, Bernard Buetow, Ingrid Pardo, Michael Mirsky, Bora Han, Bing Kuang, Allison G. Chunyk, Kevin C. Lindquist, Yik Andy Yeung, Thomas J. Van Blarcom, Sherman M. Chin, Russell G. Dushin, Marjorie Bateman, Santiago Farias, Kathy Delaria, Wei Chen, Edward Pascua, Cris Kamperschroer, Laura Aschenbrenner, Tao Geng, Amy Chen, Yi Zhang, Tracy C. Kuo, Siler H. Panowski
Antibody analytics and sequences.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18a9e93a42281e50c075eb5e86dca1b9
https://doi.org/10.1158/1535-7163.22510266.v1
https://doi.org/10.1158/1535-7163.22510266.v1
Autor:
Barbra J. Sasu, Javier Chaparro-Riggers, Pavel Strop, Arvind Rajpal, David Shelton, Jeffrey L. Wolf, Thomas G. Martin, Bernard Buetow, Ingrid Pardo, Michael Mirsky, Bora Han, Bing Kuang, Allison G. Chunyk, Kevin C. Lindquist, Yik Andy Yeung, Thomas J. Van Blarcom, Sherman M. Chin, Russell G. Dushin, Marjorie Bateman, Santiago Farias, Kathy Delaria, Wei Chen, Edward Pascua, Cris Kamperschroer, Laura Aschenbrenner, Tao Geng, Amy Chen, Yi Zhang, Tracy C. Kuo, Siler H. Panowski
ADC in vitro activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::135d03c0e236007ff9094d15e834dff8
https://doi.org/10.1158/1535-7163.22510284.v1
https://doi.org/10.1158/1535-7163.22510284.v1
Autor:
Barbra J. Sasu, Javier Chaparro-Riggers, Pavel Strop, Arvind Rajpal, David Shelton, Jeffrey L. Wolf, Thomas G. Martin, Bernard Buetow, Ingrid Pardo, Michael Mirsky, Bora Han, Bing Kuang, Allison G. Chunyk, Kevin C. Lindquist, Yik Andy Yeung, Thomas J. Van Blarcom, Sherman M. Chin, Russell G. Dushin, Marjorie Bateman, Santiago Farias, Kathy Delaria, Wei Chen, Edward Pascua, Cris Kamperschroer, Laura Aschenbrenner, Tao Geng, Amy Chen, Yi Zhang, Tracy C. Kuo, Siler H. Panowski
The restricted expression pattern of B-cell maturation antigen (BCMA) makes it an ideal tumor-associated antigen (TAA) for the treatment of myeloma. BCMA has been targeted by both CD3 bispecific antibody and antibody–drug conjugate (ADC) modalities
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53e53d5a22469996870b78467034a668
https://doi.org/10.1158/1535-7163.c.6539562.v1
https://doi.org/10.1158/1535-7163.c.6539562.v1
Autor:
Barbra J. Sasu, Javier Chaparro-Riggers, Pavel Strop, Arvind Rajpal, David Shelton, Jeffrey L. Wolf, Thomas G. Martin, Bernard Buetow, Ingrid Pardo, Michael Mirsky, Bora Han, Bing Kuang, Allison G. Chunyk, Kevin C. Lindquist, Yik Andy Yeung, Thomas J. Van Blarcom, Sherman M. Chin, Russell G. Dushin, Marjorie Bateman, Santiago Farias, Kathy Delaria, Wei Chen, Edward Pascua, Cris Kamperschroer, Laura Aschenbrenner, Tao Geng, Amy Chen, Yi Zhang, Tracy C. Kuo, Siler H. Panowski
Pharmacokinetics of BCMA bispecific and ADC in cynomolgus monkeys.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8abe79a5c112591eb1fcc450fab4ec2b
https://doi.org/10.1158/1535-7163.22510272
https://doi.org/10.1158/1535-7163.22510272
Autor:
Barbra J. Sasu, Javier Chaparro-Riggers, Pavel Strop, Arvind Rajpal, David Shelton, Jeffrey L. Wolf, Thomas G. Martin, Bernard Buetow, Ingrid Pardo, Michael Mirsky, Bora Han, Bing Kuang, Allison G. Chunyk, Kevin C. Lindquist, Yik Andy Yeung, Thomas J. Van Blarcom, Sherman M. Chin, Russell G. Dushin, Marjorie Bateman, Santiago Farias, Kathy Delaria, Wei Chen, Edward Pascua, Cris Kamperschroer, Laura Aschenbrenner, Tao Geng, Amy Chen, Yi Zhang, Tracy C. Kuo, Siler H. Panowski
T cell dynamics in response to BCMA bispecific and ADCs in cynomolgus monkeys.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4319c7228d850b35d7353d9be286236b
https://doi.org/10.1158/1535-7163.22510269.v1
https://doi.org/10.1158/1535-7163.22510269.v1
Autor:
Jeishla Melendez Matos, Samantha Green, Yuge Chun, Vuong Q. Dang, Russell G. Dushin, Paul Richardson, Jason Chen, David W. Piotrowski, Brian Paegel, Ryan Shenvi
Preparative chemical reactions that occur efficiently under dilute, buffered, aqueous conditions in the presence of biomolecules find application in ligation, peptide synthesis, polynucleotide synthesis and sequencing. However, the identification of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87367cd1372c1a65ac6dc8e368975430
https://doi.org/10.26434/chemrxiv.11977917
https://doi.org/10.26434/chemrxiv.11977917