Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Russell Bonneville"'
Autor:
Hui-Zi Chen, MD, PhD, Russell Bonneville, BS, Anoosha Paruchuri, PhD, Julie W. Reeser, PhD, Michele R. Wing, PhD, Eric Samorodnitsky, PhD, Melanie A. Krook, PhD, Amy M. Smith, BS, Thuy Dao, BS, Jharna Miya, MS, Walter Wang, BS, Lianbo Yu, PhD, Aharon G. Freud, MD, PhD, Patricia Allenby, MD, Sharon Cole, MD, Gregory Otterson, MD, Peter Shields, MD, David P. Carbone, MD, PhD, Sameek Roychowdhury, MD, PhD
Publikováno v:
JTO Clinical and Research Reports, Vol 2, Iss 4, Pp 100164- (2021)
Introduction: Relapsed SCLC is characterized by therapeutic resistance and high mortality rate. Despite decades of research, mechanisms responsible for therapeutic resistance have remained elusive owing to limited tissues available for molecular stud
Externí odkaz:
https://doaj.org/article/d41ee449b2bc4d2ab3b5a1f76d7484c9
Autor:
Jalal K. Siddiqui, Elizabeth Baskin, Mingrui Liu, Carmen Z. Cantemir-Stone, Bofei Zhang, Russell Bonneville, Joseph P. McElroy, Kevin R. Coombes, Ewy A. Mathé
Publikováno v:
BMC Bioinformatics, Vol 19, Iss 1, Pp 1-12 (2018)
Abstract Background Integration of transcriptomic and metabolomic data improves functional interpretation of disease-related metabolomic phenotypes, and facilitates discovery of putative metabolite biomarkers and gene targets. For this reason, these
Externí odkaz:
https://doaj.org/article/5c84e29ac23347538e05da558ccf4972
Publikováno v:
BMC Genomics, Vol 18, Iss 1, Pp 1-13 (2017)
Abstract Background Recent studies have suggested that combinations of multiple epigenetic modifications are essential for controlling gene expression. Despite numerous computational approaches have been developed to decipher the combinatorial epigen
Externí odkaz:
https://doaj.org/article/fa6b807c4c32425f9a6821f32b885778
Autor:
Xun Lan, Christopher Adams, Mark Landers, Miroslav Dudas, Daniel Krissinger, George Marnellos, Russell Bonneville, Maoxiong Xu, Junbai Wang, Tim H-M Huang, Gavin Meredith, Victor X Jin
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e22226 (2011)
Methyl-CpG binding domain protein sequencing (MBD-seq) is widely used to survey DNA methylation patterns. However, the optimal experimental parameters for MBD-seq remain unclear and the data analysis remains challenging. In this study, we generated h
Externí odkaz:
https://doaj.org/article/e305705ac7144892a733824cff04070b
Autor:
Anoosha Paruchuri, Lianbo Yu, Sharon Cole, Walter Wang, Hui-Zi Chen, Sameek Roychowdhury, Patricia Allenby, Amy M. Smith, Eric Samorodnitsky, Julie W. Reeser, Aharon G. Freud, Gregory A. Otterson, David P. Carbone, Jharna Miya, Michele R. Wing, Russell Bonneville, Melanie A. Krook, Peter G. Shields, Thuy Dao
Publikováno v:
JTO Clinical and Research Reports, Vol 2, Iss 4, Pp 100164-(2021)
JTO Clinical and Research Reports
JTO Clinical and Research Reports
Introduction Relapsed SCLC is characterized by therapeutic resistance and high mortality rate. Despite decades of research, mechanisms responsible for therapeutic resistance have remained elusive owing to limited tissues available for molecular studi
Autor:
Steven K. Clinton, Jharna Miya, Russell Bonneville, Thuy Dao, Dorrelyn Martin, Amy M. Smith, Aharon G. Freud, Melanie A. Krook, Hui-Zi Chen, Julie W. Reeser, Eric Samorodnitsky, Michele R. Wing, J. Paul Monk, Hannah Barker, Sameek Roychowdhury
Publikováno v:
Prostate Cancer and Prostatic Diseases. 22:624-632
Background The fibroblast growth factor receptor (FGFR) signaling pathway is activated in multiple tumor types through gene amplifications, single base substitutions, or gene fusions. Multiple small molecule kinase inhibitors targeting FGFR are curre
Autor:
Julie W. Reeser, Lianbo Yu, Hui-Zi Chen, David A. Liebner, Jharna Miya, Sameek Roychowdhury, Thuy Dao, Qishan Guo, Melanie A. Krook, Amy Smith, Michele R. Wing, Patricia Allenby, Dorrelyn Martin, Aharon G. Freud, Russell Bonneville, Eric Samorodnitsky
Publikováno v:
Oncotarget
Interdigitating dendritic cell sarcoma (IDCS) is an extremely rare cancer of dendritic cell origin that lacks a standardized treatment approach. Here, we performed genomic characterization of metastatic IDCS through whole exome sequencing (WES) of tu
Autor:
Hui-Zi Chen, Julie W. Reeser, Aharon G. Freud, Amy Smith, Eric Samorodnitsky, Melanie A. Krook, Thuy Dao, Michele R. Wing, Anoosha Paruchuri, Jharna Miya, Russell Bonneville, Patricia Allenby, Sameek Roychowdhury
Publikováno v:
JCO Precis Oncol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e073188453f0f83361f50b791320b9cf
https://europepmc.org/articles/PMC7446505/
https://europepmc.org/articles/PMC7446505/
Autor:
Lianbo Yu, Michele R. Wing, Hui-Zi Chen, Russell Bonneville, Melanie A. Krook, Julie W. Reeser, Jharna Miya, Esko A. Kautto, Sameek Roychowdhury
Publikováno v:
JCO Precision Oncology. :1-15
Purpose Microsatellite instability (MSI) is a pattern of hypermutation that occurs at genomic microsatellites and is caused by defects in the mismatch repair system. Mismatch repair deficiency that leads to MSI has been well described in several type
Autor:
Julie W. Reeser, Russell Bonneville, Wei Chen, Eric Samorodnitsky, Lianbo Yu, Sameek Roychowdhury, Thuy Dao, Melanie A. Krook, Amy M. Smith, Hui-Zi Chen, Anoosha Paruchuri, Nicholas B. Nowacki, Michele R. Wing
Publikováno v:
Mol Cancer Res
Microsatellites are short, repetitive segments of DNA, which are dysregulated in mismatch repair-deficient (MMRd) tumors resulting in microsatellite instability (MSI). MSI has been identified in many human cancer types with varying incidence, and mic