A Rapid and Reliable Absorbance Assay to Identify Drug–Drug Interactions with Thiopurine Drugs.

Autor: Russell, Drake A., Stafford, Carson, Totah, Rheem A.

Publikováno v: Metabolites (2218-1989); Dec2024, Vol. 14 Issue 12, p715, 14p

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Human METTL7B is an alkyl thiol methyltransferase that metabolizes hydrogen sulfide and captopril.

Autor: Maldonato, Benjamin J.¹, Russell, Drake A.¹, Totah, Rheem A.¹ rtotah@uw.edu

Publikováno v: Scientific Reports. 3/1/2021, Vol. 11 Issue 1, p1-13. 13p.

METTL7A and METTL7B Catalyze the Methylation of Aliphatic Thiols

Autor: Russell, Drake, Maldonato, Ben, Totah, Rheem

Publikováno v: In Free Radical Biology and Medicine 1 November 2020 159 Supplement 1:S32-S32

High-throughput cytochrome P450 loss and metabolic intermediate complex assays to aid in designing out of CYP3A inactivation.

Autor: Russell DA; Department of Medicinal Chemistry, University of Washington, Seattle, WA, United States., Cerny MA; Pharmacokinetics, Dynamics and Metabolism, Pfizer, Inc., Groton, CT, United States. Electronic address: matthew.cerny@pfizer.com.

Publikováno v: Methods in enzymology [Methods Enzymol] 2023; Vol. 690, pp. 341-368. Date of Electronic Publication: 2023 Sep 09.