Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Russ N. Fitzgerald"'
Autor:
Richard T. Matsuoka, Svetlana A. Burova, Russ N. Fitzgerald, David J. Burinsky, Byron S. Johnson, Roman Davis
Publikováno v:
Rapid Communications in Mass Spectrometry. 26:1115-1122
RATIONALE The 2-aminoaniline scaffold is of significant value to the pharmaceutical industry and is embedded in a number of pharmacophores including 2-aminoanilides and benzimidazoles. A novel application of coordination ion spray mass spectrometry (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b3f5fe6105cf9bc4813cdb2d07fda0d
https://doi.org/10.1002/rcm.6210
https://doi.org/10.1002/rcm.6210
Autor:
Roman Davis, Andrew D. Brown, Matthew J. Sharp, Bing Liu, Bobby N. Glover, Russ N. Fitzgerald, Lynda A. Jones, Kim A. Harvey, Daniel E. Patterson
Publikováno v:
Organic Process Research & Development. 13:297-302
Three efficient syntheses of sodelglitazar (1) have been developed. In particular, the third synthesis avoids the use of zinc and eliminates the resulting heavy metal waste stream as well as the potential genotoxic methanesulfonate in the two earlier
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::733f09fb456afe43dbf8e2efff278e40
https://doi.org/10.1021/op8002294
https://doi.org/10.1021/op8002294
Publikováno v:
Synthetic Communications. 37:3029-3039
A novel method for preparation of 1‐substituted benzimidazoles via reductive amination of ketones with N‐differentiated 1,2‐diaminobenzenes is described. The method appears to be general in application to acyclic and cyclic ketones, as well as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bada2b4165d81a16a61688e1cf90dc90
https://doi.org/10.1080/00397910701542996
https://doi.org/10.1080/00397910701542996
Publikováno v:
Synthetic Communications. 36:2129-2133
An improved, two‐step synthesis of efaproxiral, used in breast cancer therapy, is described, utilizing inexpensive commodity chemicals for starting materials. Selective amide formation and O‐alkylation in the presence of multireactive functional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f65138056590fbed766bd21c666f0856
https://doi.org/10.1080/00397910600636527
https://doi.org/10.1080/00397910600636527
Publikováno v:
Synthesis. 2004:1959-1962
An improved method for the formation of 2-methyl-2-aryloxypropanoic acid derivatives, an important class of compounds for the potential treatment of type II diabetes, is reported. This method offers several advantages over the existing chemistry for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab17f93750dfee2adb6e3f86f3f3225b
https://doi.org/10.1055/s-2004-829171
https://doi.org/10.1055/s-2004-829171
Autor:
James A. Marshall, Russ N. Fitzgerald
Publikováno v:
The Journal of Organic Chemistry. 64:4477-4481
A C13−22 syn,syn,syn,syn-stereopentad precursor of the cytotoxic polyketide callystatin A has been prepared. The synthesis involved BF3-promoted addition of the (M)-allenylstannane 28 to the α-methyl-β-OTBS aldehyde 8 to afford the syn,syn adduct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1884477f53db107bb764750bc05f1597
https://doi.org/10.1021/jo9902143
https://doi.org/10.1021/jo9902143
Autor:
Peter J. Dunn, Russ N. Fitzgerald, Alan John Pettman, Jannine Cobb, Joanne E. Anderson, Roman Davis
Publikováno v:
Sustainable Catalysis: Challenges and Practices for the Pharmaceutical and Fine Chemical Industries
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::512cb1b451209b8f43b04bbfc5e4315f
https://doi.org/10.1002/9781118354520.ch06
https://doi.org/10.1002/9781118354520.ch06
Autor:
Byron S, Johnson, David J, Burinsky, Svetlana A, Burova, Roman, Davis, Russ N, Fitzgerald, Richard T, Matsuoka
Publikováno v:
Rapid communications in mass spectrometry : RCM. 26(9)
The 2-aminoaniline scaffold is of significant value to the pharmaceutical industry and is embedded in a number of pharmacophores including 2-aminoanilides and benzimidazoles. A novel application of coordination ion spray mass spectrometry (CIS-MS) fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e2c09759e844ef0f29889e4cf63fc15a
https://pubmed.ncbi.nlm.nih.gov/22467462
https://pubmed.ncbi.nlm.nih.gov/22467462
Autor:
Russ N. Fitzgerald, James A. Marshall
Publikováno v:
ChemInform. 30
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::72ae4fd41a09350c3b03ce7bec5d92fd
https://doi.org/10.1002/chin.199938213
https://doi.org/10.1002/chin.199938213
Publikováno v:
ChemInform. 39
A novel method for preparation of 1‐substituted benzimidazoles via reductive amination of ketones with N‐differentiated 1,2‐diaminobenzenes is described. The method appears to be general in application to acyclic and cyclic ketones, as well as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5fe5099414c435d74f056dbc12debfd5
https://doi.org/10.1002/chin.200809134
https://doi.org/10.1002/chin.200809134