Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Ruslan A. Zukov"'
Autor:
Ulyana A. Boyarskih, Andrey A. Kechin, Alyona V. Zyuzyukina, Yevgeny A. Khrapov, Igor P. Oscorbin, Yefim Y. Alexeenok, Galina A. Avdiyuk, Ruslan A. Zukov, Nikolay E. Kushlinskii, Maksim L. Filipenko
Publikováno v:
Alʹmanah Kliničeskoj Mediciny, Vol 52, Iss 3, Pp 132-139 (2024)
Background: For effective screening of breast cancer patients for candidates for target therapy with alpelisib, it is necessary to identify activating somatic mutations in the PIK3CA gene by allele specific polymerase chain reaction (PCR); this requi
Externí odkaz:
https://doaj.org/article/066dd6030c43452ba3308b2541346f48
Autor:
Maria I. Volkova, Alexey S. Kalpinskiy, Olesya A. Goncharova, Konstantin V. Menshikov, Elena V. Karabina, Aleksand S. Dergunov, Natalya I. Polshina, Elena N. Alexandrova, Andrey A. Lebedinets, Alexey К. Panov, Alexander V. Sultanbaev, Evgeny A. Usynin, Mikhail V. Volkonskiy, Viktorya V. Mikhalyuk, Ruslan A. Zukov, Yulia V. Anzhiganova, Magomed A. Gusniev, Elena N. Igumnova, Svetlana V. Kuzmicheva, Ilya A. Pokataev, Anna S. Olshanskaya, Natalia I. Pervakova, Elvira L. Parsadanova, Tatyana A. Sannikova, Alexandr A. Bystrov, Daria M. Dubovichenko, Mukhitova R. Miliausha, Viacheslav A. Chubenko, Konstantin A. Shkret, Mariya N. Gorshenina, Mavzhuda К. Davlatova, Alina E. Kosareva, Olga A. Lutoshkina, Oxana A. Maslova, Maria V. Makhnutina, Anna V. Mishina, Makhabbat Zh. Murzalina, Oksana A. Podyacheva, Sergey A. Kalinin, Ovsep A. Mailyan, Alfiya R. Safarova, Ksenia O. Semenova, Mariya A. Strokova, Ekaterina Yu. Urashkina, Olesya S. Shmygina
Publikováno v:
Современная онкология, Vol 26, Iss 1, Pp 39-47 (2024)
Aim To evaluate the safety and toxicity of lenvatinib with pembrolizumab in unselected patients with advanced renal cell carcinoma (RCC). Materials and methods. The Russian phase IV observational study included 151 patients with advanced RCC who r
Externí odkaz:
https://doaj.org/article/b8f04fb084054d4fa93d3b87907a155b
Autor:
Anna S. Kichkailo, Andrey A. Narodov, Maria A. Komarova, Tatiana N. Zamay, Galina S. Zamay, Olga S. Kolovskaya, Evgeniy E. Erakhtin, Yury E. Glazyrin, Dmitry V. Veprintsev, Roman V. Moryachkov, Vladimir V. Zabluda, Irina Shchugoreva, Polina Artyushenko, Vladimir A. Mironov, Dmitry I. Morozov, Vladimir A. Khorzhevskii, Anton V. Gorbushin, Anastasia A. Koshmanova, Elena D. Nikolaeva, Igor P. Grinev, Ivan I. Voronkovskii, Daniil S. Grek, Kirill V. Belugin, Alexander A. Volzhentsev, Oleg N. Badmaev, Natalia A. Luzan, Kirill A. Lukyanenko, Georgy Peters, Ivan N. Lapin, Andrey K. Kirichenko, Petr V. Konarev, Evgeny V. Morozov, Gleb G. Mironov, Ana Gargaun, Darija Muharemagic, Sergey S. Zamay, Elena V. Kochkina, Maya A. Dymova, Tatiana E. Smolyarova, Alexey E. Sokolov, Andrey A. Modestov, Nikolay A. Tokarev, Nikolay V. Shepelevich, Anastasia V. Ozerskaya, Natalia G. Chanchikova, Alexey V. Krat, Ruslan A. Zukov, Varvara I. Bakhtina, Pavel G. Shnyakin, Pavel A. Shesternya, Valery A. Svetlichnyi, Marina M. Petrova, Ivan P. Artyukhov, Felix N. Tomilin, Maxim V. Berezovski
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 32, Iss , Pp 267-288 (2023)
Here, we present DNA aptamers capable of specific binding to glial tumor cells in vitro, ex vivo, and in vivo for visualization diagnostics of central nervous system tumors. We selected the aptamers binding specifically to the postoperative human gli
Externí odkaz:
https://doaj.org/article/f65de7532b0f4df1b79a409702872882
Publikováno v:
Современная онкология, Vol 24, Iss 3, Pp 380-383 (2022)
Among the multiple primary malignant tumors, breast cancer is the most common and in most cases it is combined with the second mammary gland, uterine body, stomach, colon, skin and ovary. Breast angiosarcoma is a very rare disease with unfavorable pr
Externí odkaz:
https://doaj.org/article/5322485b7e1149dbaca18833e6b017d5
Autor:
Olga S. Kolovskaya, Alena V. Zyuzyukina, Justin P. Dassie, Galina S. Zamay, Tatiana N. Zamay, Nina V. Boyakova, Vladimir A. Khorzhevskii, Daria A. Kirichenko, Ivan N. Lapin, Irina A. Shchugoreva, Polina V. Artyushenko, Felix N. Tomilin, Dmitry V. Veprintsev, Yury E. Glazyrin, Zoran Minic, Vladimir K. Bozhenko, Elena A. Kudinova, Yana Y. Kiseleva, Alexey V. Krat, Eugene V. Slepov, Anton S. Bukatin, Ruslan A. Zukov, Pavel A. Shesternya, Maxim V. Berezovski, Paloma H. Giangrande, Anna S. Kichkailo
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Introduction: Breast cancer (BC) diagnostics lack noninvasive methods and procedures for screening and monitoring disease dynamics. Admitted CellSearch® is used for fluid biopsy and capture of circulating tumor cells of only epithelial origin. Here
Externí odkaz:
https://doaj.org/article/268c1b8652ec488c9d438b2c4ef707a6
Autor:
Tatyana N. Sokolova, Tatyana I. Solov'eva, Svetlana N. Aleksakhina, Grigorii A. Janus, Alla Goryainova, Mark I. Gluzman, Rashida V. Orlova, Anastasiya I. Stukan, Ruslan A. Zukov, Alena V. Zyuzyukina, Yulia N. Murunova, Aleksandr V. Sultanbaev, Elena N. Vorobeva, Leonid M. Mikhaevich, Victoria N. Pyliv, Anna N. Lysenko, Zarema K. Khachmamuk, Andrey E. Kozlov, Sergey Y. Bakharev, Shahen G. Parsyan, Elena I. Rossokha, Leri D. Osidze, Irina S. Shumskaya, Anna V. Agaeva, Tatiana A. Kasmynina, Veronika V. Klimenko, Kamila T. Akhmetgareeva, Almira A. Vakhitova, Madina D. Chakhkieva, Vadim N. Dmitriev, Yana I. Bakshun, Alexey E. Vasilyev, Dunya D. Gasimly, Nadezhda A. Kravchenko, Dmitriy A. Maksimov, Alfia I. Nesterova, Ineza O. Sharvashidze, Christina H. Gadzaova, Galina G. Rakhmankulova, Zaur M. Khamgokov, Irina K. Amirkhanova, Ludmila V. Bembeeva, Vladimir I. Vladimirov, Oleg L. Petrenko, Natalia G. Ruskova, Ekaterina L. Serikova, Ksenia S. Subbotina, Svetlana A. Tkachenko, Victor L. Chang, Sanal P. Erdniev, Victoria S. Barbara, Anna V. Vasilevskaya, Yulia V. Mikheeva, Nataliya O. Popova, Ekaterina P. Startseva, Anastasia V. Fateeva, Denis Y. Yukalchuk, Anna A. Grechkina, Khedi S. Musaeva, Svetlana V. Odintsova, Alena S. Stel'makh, Petimat I. Khabibulaeva, Alina G. Khlobystina, Kseniya A. Shvaiko, Elena A. Basova, Irina A. Bogomolova, Marina B. Bolieva, Viktor E. Goldberg, Marianna V. Kibisheva, Konstantin V. Menshikov, Dmitrii V. Ryazanov, Mariya L. Stepanova, Yana A. Udalova, Aleksandr V. Shkradyuk, Yana S. Chapko, Anna A. Shchukina, Idris M. Khabriev, Dmitrii V. Kirtbaya, Alexey M. Degtyarev, Aleksandr A. Epkhiev, Yana A. Tyugina, Mirza A. Murachuev, Aleksandr V. Togo, Aglaya G. Ievleva, Evgenii N. Imyanitov
Publikováno v:
Современная онкология, Vol 24, Iss 1, Pp 12-23 (2022)
Background. By 2020, breast cancer (BC) has become the most frequent malignancy in the world. The most common type of BC is HR+/HER2-negative cancer,2540% of which harbors PIK3CA mutations that affect the catalytic subunit of the PI3K protein. PIK3CA
Externí odkaz:
https://doaj.org/article/ac2dc051d6cd4d1686520ce6a60f66af
Autor:
Dmitry Morozov, Vladimir Mironov, Roman V. Moryachkov, Irina A. Shchugoreva, Polina V. Artyushenko, Galina S. Zamay, Olga S. Kolovskaya, Tatiana N. Zamay, Alexey V. Krat, Dmitry S. Molodenskiy, Vladimir N. Zabluda, Dmitry V. Veprintsev, Alexey E. Sokolov, Ruslan A. Zukov, Maxim V. Berezovski, Felix N. Tomilin, Dmitri G. Fedorov, Yuri Alexeev, Anna S. Kichkailo
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 25, Iss , Pp 316-327 (2021)
Aptamers are short, single-stranded DNA or RNA oligonucleotide molecules that function as synthetic analogs of antibodies and bind to a target molecule with high specificity. Aptamer affinity entirely depends on its tertiary structure and charge dist
Externí odkaz:
https://doaj.org/article/61ad209c4876418dbedaeab67898ea1d
Autor:
Tatiana N. Sokolova, Svetlana N. Aleksakhina, Grigoriy A. Yanus, Aleksandr V. Sultanbaev, Konstantin V. Menshikov, Anna N. Lysenko, Ruslan A. Zukov, Alena V. Zyuzyukina, Yulia N. Murunova, Elena I. Rossokha, Sergey Y. Bakharev, Elena A. Basova, Tatiana A. Kasmynina, Irina S. Shumskaya, Yana I. Bakshun, Khedi S. Musaeva, Alfia I. Khasanova, Vadim N. Dmitriev, Marina B. Bolieva, Christina H. Gadzaova, Oleg L. Petrenko, Dmitriy A. Maksimov, Vladimir I. Vladimirov, Viktor E. Goldberg, Nataliya O. Popova, Marianna V. Kibisheva, Zaur M. Khamgokov, Alexey E. Vasilyev, Aglaya G. Iyevleva, Evgeny N. Imyanitov
Publikováno v:
Современная онкология, Vol 23, Iss 1, Pp 61-67 (2021)
Relevance. PIK3CA belongs to the top three most frequently mutated genes in breast cancer (BC), especially in estrogen receptor (ER) positive, HER2 negative BC subtype. With an approval of selective PI3K-alpha inhibitor, alpelisib, this alteration ha
Externí odkaz:
https://doaj.org/article/49ac17b627194a6ea7e6222ff26d5a94
Autor:
Galina S. Zamay, Tatiana I. Ivanchenko, Tatiana N. Zamay, Valentina L. Grigorieva, Yury E. Glazyrin, Olga S. Kolovskaya, Irina V. Garanzha, Andrey A. Barinov, Alexey V. Krat, Gleb G. Mironov, Ana Gargaun, Dmitry V. Veprintsev, Sergey S. Bekuzarov, Andrey K. Kirichenko, Ruslan A. Zukov, Marina M. Petrova, Andrey A. Modestov, Maxim V. Berezovski, Anna S. Zamay
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 6, Iss , Pp 150-162 (2017)
Nucleic acid aptamers are becoming popular as molecular probes for identification and imaging pathology and, at the same time, as a convenient platform for targeted therapy. Recent studies have shown that aptamers may be effectively used for tumor ch
Externí odkaz:
https://doaj.org/article/6c14b9fd44a045fcbb7b57e303f76361
Autor:
Tatiana N. Zamay, Alexander K. Starkov, Olga S. Kolovskaya, Galina S. Zamay, Dmitry V. Veprintsev, Natalia Luzan, Elena D. Nikolaeva, Kirill A. Lukyanenko, Polina V. Artyushenko, Irina A. Shchugoreva, Yury E. Glazyrin, Anastasia A. Koshmanova, Alexey V. Krat, Dariya S. Tereshina, Sergey S. Zamay, Yuriy S. Pats, Ruslan A. Zukov, Felix N. Tomilin, Maxim V. Berezovski, Anna S. Kichkailo
Publikováno v:
Nucleic Acid Therapeutics. 32:497-506
Cisplatin is an effective drug for treating various cancer types. However, it is highly toxic for both healthy and tumor cells. Therefore, there is a need to reduce its therapeutic dose and increase targeted bioavailability. One of the ways to achiev