Edible mushroom (Pleurotus cornucopiae) extract vs. glibenclamide on alloxan induced diabetes: sub-acute in vivo study of Nrf2 expression and renal toxicity.

Autor: Uzomba, Chinedu Godwin¹ uzomba.godwin@funai.edu.ng, Ezemagu, Uchenna Kenneth¹, Ofoegbu, Mary-Sonia¹, Lydia, Njoku¹, Goodness, Essien¹, Emelike, Chinedum², Obinna, Uchewa¹, Nwafor, Alo Joseph¹, Mbajiorgu, Ejikeme Felix³

Publikováno v: Anatomy & Cell Biology. Sep2024, Vol. 57 Issue 3, p446-458. 13p.

In-vitro metabolism of celecoxib, a cyclooxygenase-2 inhibitor, by allelic variant forms of human liver microsomal cytochrome P450 2C9: correlation with CYP2C9 genotype and in-vivo pharmacokinetics

Autor: Cuyue Tang, De Schepper Pj, Gelmann A, Woolf Ej, De Lepeleire I, Sandhu P, Greenberg He, Schwartz Ji, Rose Mj, Van Hecken A, Qin Mei, Rodrigues Ad, Rushmore Th, Shou M, Ebel Dl

Publikováno v: Pharmacogenetics. 11(3)

In-vitro studies were conducted to assess the impact of CYP2C9 genotype on the metabolism (methyl hydroxylation) and pharmacokinetics of celecoxib, a novel cyclooxygenase-2 inhibitor and CYP2C9 substrate. When compared to cDNA-expressed wild-type CYP

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b65a354c77568e58f18a6bc23bf8fd6
https://pubmed.ncbi.nlm.nih.gov/11337938

Toward a systems approach to the human cytochrome P450 ensemble: interactions between CYP2D6 and CYP2E1 and their functional consequences.

Autor: Davydov DR; Department of Chemistry, Washington State University, Pullman, WA 99164, U.S.A. dmrdavyd@gmail.com., Davydova NY; Department of Chemistry, Washington State University, Pullman, WA 99164, U.S.A., Rodgers JT; Department of Chemistry, Washington State University, Pullman, WA 99164, U.S.A., Rushmore TH; Department of Pharmaceutical Sciences, University of the Sciences, Philadelphia, PA 19104, U.S.A., Jones JP; Department of Chemistry, Washington State University, Pullman, WA 99164, U.S.A.

Publikováno v: The Biochemical journal [Biochem J] 2017 Oct 10; Vol. 474 (20), pp. 3523-3542. Date of Electronic Publication: 2017 Oct 10.

Impaired bone morphogenetic protein (BMP) signaling pathways disrupt decidualization in endometriosis.

Autor: Liao, Zian^1,2,3,4 (AUTHOR), Tang, Suni^1,4 (AUTHOR), Jiang, Peixin^1,5 (AUTHOR), Geng, Ting¹ (AUTHOR), Cope, Dominique I.^1,4 (AUTHOR), Dunn, Timothy N.^6,7 (AUTHOR), Guner, Joie⁸ (AUTHOR), Radilla, Linda Alpuing⁶ (AUTHOR), Guan, Xiaoming⁶ (AUTHOR), Monsivais, Diana^1,4 (AUTHOR) dmonsiva@bcm.edu

Publikováno v: Communications Biology. 2/24/2024, Vol. 7 Issue 1, p1-19. 19p.

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