Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Rushikesh Sable"'
Autor:
Rushikesh Sable, Nithya Jambunathan, Sitanshu Singh, Sandeep Pallerla, Konstantin G Kousoulas, Seetharama Jois
Publikováno v:
BioTechniques, Vol 65, Iss 3, Pp 149-157 (2018)
Protein–protein interactions (PPI) by homo-, hetero- or oligo-merization in the cellular environment regulate cellular processes. PPI can be inhibited by antibodies, small molecules or peptides, and this inhibition has therapeutic value. A recently
Externí odkaz:
https://doaj.org/article/3ed450dac3884a9993c31e64ffbd547e
Autor:
Rushikesh Sable, Seetharama Jois
Publikováno v:
Molecules, Vol 20, Iss 6, Pp 11569-11603 (2015)
Blocking protein-protein interactions (PPI) using small molecules or peptides modulates biochemical pathways and has therapeutic significance. PPI inhibition for designing drug-like molecules is a new area that has been explored extensively during th
Externí odkaz:
https://doaj.org/article/5dfca8faddfb4f8a84d45fef30ac9264
Autor:
Dandan Li, Anne M. Miermont, Rushikesh Sable, Humair S. Quadri, Lesley A. Mathews Griner, Scott E. Martin, Taivan Odzorig, Soumita De, Marc Ferrer, Astin S. Powers, Stephen M. Hewitt, Udo Rudloff
Publikováno v:
Molecular Cancer Research. 21:316-331
Combinatorial molecular therapy in pancreatic ductal adenocarcinoma (PDAC) has yielded largely disappointing results in clinical testing to-date as a multitude of adaptive resistance mechanisms is making selection of patients via molecular markers th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e441393292e8ea0306d41af0f99aa43f
https://doi.org/10.1158/1541-7786.mcr-21-1036
https://doi.org/10.1158/1541-7786.mcr-21-1036
Autor:
Udo Rudloff, Stephen M. Hewitt, Astin S. Powers, Marc Ferrer, Soumita De, Taivan Odzorig, Scott E. Martin, Lesley A. Mathews Griner, Humair S. Quadri, Rushikesh Sable, Anne M. Miermont, Dandan Li
Secondary validation of candidate genes.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fe0202c8c1b1c2f47cd5bfd9278fde5
https://doi.org/10.1158/1541-7786.22552189
https://doi.org/10.1158/1541-7786.22552189
Autor:
Udo Rudloff, Stephen M. Hewitt, Astin S. Powers, Marc Ferrer, Soumita De, Taivan Odzorig, Scott E. Martin, Lesley A. Mathews Griner, Humair S. Quadri, Rushikesh Sable, Anne M. Miermont, Dandan Li
Lists of cell lines, antibodies, RNAi kinome screen; and matrix drug combination.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da43ec6520c5ea5999715ba8cfa37149
https://doi.org/10.1158/1541-7786.22552171.v1
https://doi.org/10.1158/1541-7786.22552171.v1
Autor:
Pravin Parajuli, Achyut Dahal, Rushikesh Sable, Leeza Shrestha, Seetharama D. Jois, Veena Taneja, Ted J. Gauthier
Publikováno v:
Chem Biol Drug Des
Peptides were designed to inhibit the protein-protein interaction of CD2 and CD58 to modulate the immune response. This work involved the design and synthesis of eight different peptides by replacing each amino acid residue in peptide 6 with alanine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7bb6074d6d73014a232190d740d22bc
https://doi.org/10.1111/cbdd.13797
https://doi.org/10.1111/cbdd.13797
Autor:
Raul Calvo, Noel Southall, Lixin Fan, Chan Young Ock, Keyur Talsania, Clayton Yates, Taylor Aiken, Yansong Bian, Zachary Knotts, Yongmei Zhao, Jesse M. Jaynes, Jason White, Abisola Abisoye-Ogunniyan, Taivan Odzorig, Anghesom Ghebremedhin, Myagmarjav Dashnyam, Anton Simeonov, Sarangan Ravichandran, Nathan Pate, Amber E. de Groot, Michael Ronzetti, Xin Hu, Vicky Chen, Jelani C. Zarif, Henry Lopez, Bolormaa Baljinnyam, Parimal Kumar, Dandan Li, Natalia de Val, Theresa Guerin, Wendy Bautista, Ahmad Bin Salam, Rushikesh Sable, Juan J. Marugan, Marc Ferrer, Serguei Kozlov, Victoria Nguyen, Monika Mehta, Balasubramanyam Karanam, Ruksana Amin, Mones Abu-Asab, Udo Rudloff, Anju Singh
Publikováno v:
Sci Transl Med
Solid tumors elicit a detectable immune response including the infiltration of tumor-associated macrophages (TAMs). Unfortunately, this immune response is co-opted into contributing toward tumor growth instead of preventing its progression. We seek t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::513d18826af0875f5379d90cda6894d2
https://doi.org/10.1126/scitranslmed.aax6337
https://doi.org/10.1126/scitranslmed.aax6337
Autor:
Seetharama D. Jois, Sitanshu S. Singh, Nithya Jambunathan, Rushikesh Sable, Konstantin G. Kousoulas, Sandeep Pallerla
Publikováno v:
Biotechniques
Protein–protein interactions (PPI) by homo-, hetero- or oligo-merization in the cellular environment regulate cellular processes. PPI can be inhibited by antibodies, small molecules or peptides, and this inhibition has therapeutic value. A recently
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7d648ef6ab04767e6217cd60af1ab7b
http://europepmc.org/articles/PMC6770473
http://europepmc.org/articles/PMC6770473
Autor:
Shanthi Kanthala, Seetharama D. Jois, Sandeep Pallerla, Rushikesh Sable, Yong-Yu Liu, Sitanshu S. Singh
Publikováno v:
Oncotarget
// Shanthi P. Kanthala 1 , Yong-Yu Liu 1 , Sitanshu Singh 1 , Rushikesh Sable 1 , Sandeep Pallerla 1 and Seetharama D. Jois 1 1 Basic Pharmaceutical Sciences, School of Pharmacy, University of Louisiana at Monroe, Monroe LA 71201, USA Correspondence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::156d86bfb02b033403c89313fbbb6b4c
https://doi.org/10.18632/oncotarget.19013
https://doi.org/10.18632/oncotarget.19013
Autor:
Thomas Durek, Seetharama D. Jois, David J. Craik, Ted J. Gauthier, Sandeep Pallerla, Veena Taneja, Rushikesh Sable
Publikováno v:
ACS Chemical Biology. 11:2366-2374
The interaction between the cell-cell adhesion proteins CD2 and CD58 plays a crucial role in lymphocyte recruitment to inflammatory sites, and inhibitors of this interaction have potential as immunomodulatory drugs in autoimmune diseases. Peptides fr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::318d18f084c625e3b2f47a4e0de2658b
https://doi.org/10.1021/acschembio.6b00486
https://doi.org/10.1021/acschembio.6b00486