Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Rushd Khalaf"'
Autor:
Rushd Khalaf, Neil Mody, Bruno F. Marques, Steven M. Cramer, Christopher D. Afdahl, Richard C. Willson, Jennifer M. Pollard, Eike Zimmermann, Jan Griesbach, Divya Chandra, Charles A. Haynes, Kannan Sankar, Ujwal Patil, Jonathan Coffman, Hasan Mohammad, Joelle Khouri, Minni Aswath, Jasper C. Lin, Lars Pampel, Alexander Hanke, Siddharth Parimal, David J. Roush, Francis Insaidoo, Saeed Izadi, Raquel Orozco, Soundara Soundararajan, Nihal Tugcu, Gisela Ferreira, Tingting Cui, John P. Welsh, Jainik Panchal, Ambrose Williams, Stefan Hepbildikler, Xuan Hong, Julie Robinson, Marco A. Blanco, John E. Schiel, Jared A. Delmar, Benjamin T. Walters
Publikováno v:
Biotechnology and Bioengineering. 117:2100-2115
Biopharmaceutical product and process development do not yet take advantage of predictive computational modeling to nearly the degree seen in industries based on smaller molecules. To assess and advance progress in this area, spirited coopetition (mu
Autor:
Gianluca Buffolino, Nicola Forrer, David Gétaz, Alessandro Butté, Massimo Morbidelli, Rushd Khalaf, Susanna Bernardi
Publikováno v:
Journal of Chromatography A. 1397:11-18
The purification of therapeutic peptides is most often performed using one or more reversed phase chromatography steps. This ensures high purities while keeping the costs of purification under control. In this paper, a doped reversed phase chromatogr
Publikováno v:
Journal of chromatography. A. 1471
Ion exchange chromatography materials functionalized with polyelectrolyte brushes (PEB) are becoming an integral part of many protein purification steps. Adsorption onto these materials is different than that onto traditional materials, due to the 3D
Autor:
Julia Heymann, Massimo Morbidelli, Florence Monard, Xavier LeSaout, Matteo Costioli, Rushd Khalaf
Publikováno v:
Journal of chromatography. A. 1459
This work describes the development of a model-based high-throughput design (MHD) tool for the operating space determination of a chromatographic cation-exchange protein purification process. Based on a previously developed thermodynamic mechanistic
A novel multicomponent adsorption equilibrium model for proteins on ion-exchange resins is developed on a statistical thermodynamic basis including surface coverage effects and protein-resin and protein-protein interactions. The resulting model exhib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee895de3778b0893391cbaba1fdcd18d
http://hdl.handle.net/11311/1013727
http://hdl.handle.net/11311/1013727
Publikováno v:
Journal of chromatography. A. 1425
The analytical description and quantification of peptide solutions is an essential part in the quality control of peptide production processes and in peptide mapping techniques. Traditionally, an important tool is analytical reversed phase liquid chr
Publikováno v:
Journal of chromatography. A. 1407
Reversed-phase (RP) chromatography is one of the main tools for the preparative purification of therapeutic peptides. In previous works [1] , [2] , a new type of RP chromatography, doped reversed-phase chromatography (DRP) was presented. By adding sm
WOS: 000350930200002
PubMed ID: 25683627
A new strong cation exchanger (SCX) monolithic column was synthesized by at-line surface modification of a cryogel prepared by copolymerization of 2-hydroxyethylmethacrylate (HEMA) and glycidyl-metha
PubMed ID: 25683627
A new strong cation exchanger (SCX) monolithic column was synthesized by at-line surface modification of a cryogel prepared by copolymerization of 2-hydroxyethylmethacrylate (HEMA) and glycidyl-metha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c765f23b7fb8f55ec8a576f01e269cd5
https://hdl.handle.net/11480/3963
https://hdl.handle.net/11480/3963
Autor:
Rushd Khalaf, Davide Moscatelli, Patrizia Bossolasco, Paolo Bigini, Massimo Tortarolo, Massimo Morbidelli, Lidia Cova, Monica Lupi, Leopoldo Sitia, Vincenzo Silani, Ruggiero Pesce, Paolo Ubezio, Laura Colombo, Valentina Diana, Mario Salmona, Daniela Giardino, Raffaele Ferrari
Publikováno v:
Nanotechnology. 24:245603
Efficient application of stem cells to the treatment of neurodegenerative diseases requires safe cell tracking to follow stem cell fate over time in the host environment after transplantation. In this work, for the first time, fluorescent and biocomp