Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Rushad Karanjawala"'
Autor:
Bin Ye, Yuo-Ling Chou, Rushad Karanjawala, Wheeseong Lee, Shou-Fu Lu, Kenneth J. Shaw, Steven Jones, Dao Lentz, Amy Liang, Jih-Lie Tseng, Qingyu Wu, Zuchun Zhao
Publikováno v:
Bioorganicmedicinal chemistry letters. 14(3)
Compound 2 was identified by high throughput screening as a novel PAI-1 inhibitor. Systematic optimization of the A, B, and C segments of 2 resulted in the identification of a more potent compound 39 with good oral bioavailability. The synthesis and
Autor:
Bin Ye, Damian O. Arnaiz, Yuo-Ling Chou, Brian D. Griedel, Rushad Karanjawala, Wheeseong Lee, Michael M. Morrissey, Karna L. Sacchi, Steven T. Sakata, Kenneth J. Shaw, Shung C. Wu, Zuchun Zhao, Marc Adler, Sarah Cheeseman, William P. Dole, Janice Ewing, Richard Fitch, Dao Lentz, Amy Liang, David Light
Publikováno v:
Journal of Medicinal Chemistry; Jun2007, Vol. 50 Issue 13, p2967-2980, 14p