Beyond Genetics: Metastasis as an Adaptive Response in Breast Cancer

Autor: Ruscitto, F., Roda, N., Priami, C., Migliaccio, E., Pelicci, P.G.

Publikováno v: International journal of molecular sciences. 23(11)

Metastatic disease represents the primary cause of breast cancer (BC) mortality, yet it is still one of the most enigmatic processes in the biology of this tumor. Metastatic progression includes distinct phases: invasion, intravasation, hematogenous

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::b81228955378cd12c9bff00422f87d41
https://pubmed.ncbi.nlm.nih.gov/35682953

Aberrant activation of p53/p66Shc-mInsc axis increases asymmetric divisions and attenuates proliferation of aged mammary stem cells.

Autor: Priami C; European Institute of Oncology (IEO) IRCCS, Via Ripamonti 435, 20141, Milan, Italy., Montariello D; European Institute of Oncology (IEO) IRCCS, Via Ripamonti 435, 20141, Milan, Italy., De Michele G; European Institute of Oncology (IEO) IRCCS, Via Ripamonti 435, 20141, Milan, Italy., Ruscitto F; European Institute of Oncology (IEO) IRCCS, Via Ripamonti 435, 20141, Milan, Italy., Polazzi A; European Institute of Oncology (IEO) IRCCS, Via Ripamonti 435, 20141, Milan, Italy., Ronzoni S; European Institute of Oncology (IEO) IRCCS, Via Ripamonti 435, 20141, Milan, Italy., Bertalot G; European Institute of Oncology (IEO) IRCCS, Via Ripamonti 435, 20141, Milan, Italy.; U.O.M. Anatomia ed Istologia Patologica, Ospedale Santa Chiara, Largo Medaglie d'Oro 9, 38122, Trento, Italy., Binelli G; Department of Biotechnology and Life Sciences, University of Insubria, Via Dunant 3, 21100, Varese, Italy., Gambino V; European Institute of Oncology (IEO) IRCCS, Via Ripamonti 435, 20141, Milan, Italy.; Department of Oncology and Hemato-Oncology, University of Milan, Via Santa Sofia 9, 20142, Milan, Italy., Luzi L; European Institute of Oncology (IEO) IRCCS, Via Ripamonti 435, 20141, Milan, Italy., Mapelli M; European Institute of Oncology (IEO) IRCCS, Via Ripamonti 435, 20141, Milan, Italy., Giorgio M; European Institute of Oncology (IEO) IRCCS, Via Ripamonti 435, 20141, Milan, Italy.; Department of Biomedical Sciences, University of Padua, Via Bassi 58/B, 35131, Padova, Italy., Migliaccio E; European Institute of Oncology (IEO) IRCCS, Via Ripamonti 435, 20141, Milan, Italy. enrica.migliaccio@ieo.it., Pelicci PG; European Institute of Oncology (IEO) IRCCS, Via Ripamonti 435, 20141, Milan, Italy. piergiuseppe.pelicci@ieo.it.; Department of Oncology and Hemato-Oncology, University of Milan, Via Santa Sofia 9, 20142, Milan, Italy. piergiuseppe.pelicci@ieo.it.

Publikováno v: Cell death and differentiation [Cell Death Differ] 2022 Dec; Vol. 29 (12), pp. 2429-2444. Date of Electronic Publication: 2022 Jun 23.

Characteristics and patterns of care of endometrial cancer before and during COVID-19 pandemic.

Autor: Bogani G; Gynecologic Oncology Unit, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Milan, Italy. giorgiobogani@yahoo.it., Scambia G; Gynecologic Oncology Unit, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy., Cimmino C; Department of Obstetrics and Gynaecology, University of Insubria, F. chia.cimmino@gmail.com Del Ponte Hospital, Varese, Italy. chia.cimmino@gmail.com., Fanfani F; Gynecologic Oncology Unit, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy., Costantini B; Gynecologic Oncology Unit, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy., Loverro M; Gynecologic Oncology Unit, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy., Ferrandina G; Gynecologic Oncology Unit, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy., Landoni F; Department of Obstetrics and Gynaecology, San Gerardo Hospital, Monza, Italy., Bazzurini L; Department of Obstetrics and Gynaecology, San Gerardo Hospital, Monza, Italy., Grassi T; Department of Obstetrics and Gynaecology, San Gerardo Hospital, Monza, Italy., Vitobello D; Unit of Gynecology, Humanitas Cancer Center, Humanitas Clinical and Research Center - IRCCS, Milan, Italy., Siesto G; Unit of Gynecology, Humanitas Cancer Center, Humanitas Clinical and Research Center - IRCCS, Milan, Italy., Perrone AM; Unit of Gynecology, AOU S. Orsola-Malpighi, Bologna, Italy., Zanagnolo V; Department of Gynecologic Oncology, IEO, European Institute of Oncology IRCCS, Milan, Italy., De Iaco P; Unit of Gynecology, AOU S. Orsola-Malpighi, Bologna, Italy., Multinu F; Department of Gynecologic Oncology, IEO, European Institute of Oncology IRCCS, Milan, Italy., Ghezzi F; Department of Obstetrics and Gynaecology, University of Insubria, F. Del Ponte Hospital, Varese, Italy., Casarin J; Department of Obstetrics and Gynaecology, University of Insubria, F. Del Ponte Hospital, Varese, Italy., Berretta R; Department of Obstetrics and Gynaecology, University of Parma, Parma, Italy., Capozzi VA; Department of Obstetrics and Gynaecology, University of Parma, Parma, Italy., Zupi E; Department of Obstetrics and Gynaecology, University of Siena, Siena, Italy., Centini G; Department of Obstetrics and Gynaecology, University of Siena, Siena, Italy., Pellegrino A; Department of Obstetrics and Gynaecology, ASST Lecco - Ospedale Alessandro Manzoni, Lecco, Italy., Corso S; Department of Obstetrics and Gynaecology, ASST Lecco - Ospedale Alessandro Manzoni, Lecco, Italy., Stevenazzi G; Department of Obstetrics and Gynaecology, ASST OVEST MI, Legnano (Milan) Hospital, Legnano, Italy., Montoli S; Department of Obstetrics and Gynaecology, ASST OVEST MI, Legnano (Milan) Hospital, Legnano, Italy., Boschi AC; Department of Obstetrics and Gynaecology, AUSL Romagna, Ospedale 'Santa Maria delle Croci', Ravenna, Italy., Comerci G; Department of Obstetrics and Gynaecology, AUSL Romagna, Ospedale 'Santa Maria delle Croci', Ravenna, Italy., Greco P; Clinica Ostetrica e Ginecologica - Dipartimento Scienze Mediche - Università di Ferrara, Ferarra, Italy., Martinello R; Clinica Ostetrica e Ginecologica - Dipartimento Scienze Mediche - Università di Ferrara, Ferarra, Italy., Sopracordevole F; Gynecological Oncology Unit, Centro di Riferimento Oncologico - National Cancer Institute, Aviano, Italy., Giorda G; Gynecological Oncology Unit, Centro di Riferimento Oncologico - National Cancer Institute, Aviano, Italy., Simoncini T; Division of Obstetrics and Gynecology, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy., Caretto M; Division of Obstetrics and Gynecology, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy., Sartori E; Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy., Ferrari F; Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy., Cianci A; Department of General Surgery and Medical Surgical Specialties, Gynecological Clinic, University of Catania, Catania, Italy., Sarpietro G; Department of General Surgery and Medical Surgical Specialties, Gynecological Clinic, University of Catania, Catania, Italy., Matarazzo MG; Department of General Surgery and Medical Surgical Specialties, Gynecological Clinic, University of Catania, Catania, Italy., Zullo F; Department of Obstetrics and Gynaecology, Azienda Ospedaliera Universitaria - Federico II, Naples, Italy., Bifulco G; Department of Obstetrics and Gynaecology, Azienda Ospedaliera Universitaria - Federico II, Naples, Italy., Morelli M; Department of Obstetrics and Gynaecology, AO 'S.S. Annunziata', Cosenza, Italy., Ferrero A; Academic Department of Obstetrics and Gynecology, Mauriziano Hospital, Torino, Italy., Biglia N; Academic Department of Obstetrics and Gynecology, Mauriziano Hospital, Torino, Italy., Barra F; Academic Unit of Obstetrics and Gynecology, IRCCS Ospedale Policlinico San Martino, Genova, Italy., Ferrero S; Academic Unit of Obstetrics and Gynecology, IRCCS Ospedale Policlinico San Martino, Genova, Italy., Leone Roberti Maggiore U; Gynecologic Oncology Unit, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Milan, Italy., Cianci S; Unit of Gynecology and Obstetrics, Department of Human Pathology in Adulthood and Childhood 'G. Barresi', University Hospital G. Martino, University of Messina, Messina, Italy., Chiantera V; Department of Gynecologic Oncology, University of Palermo, Palermo, Italy., Ercoli A; Unit of Gynecology and Obstetrics, Department of Human Pathology in Adulthood and Childhood 'G. Barresi', University Hospital G. Martino, University of Messina, Messina, Italy., Sozzi G; Department of Gynecologic Oncology, University of Palermo, Palermo, Italy., Martoccia A; Department of Obstetrics and Gynaecology, AOR San Carlo, Potenza, Italy., Schettini S; Department of Obstetrics and Gynaecology, AOR San Carlo, Potenza, Italy., Orlando T; Department of Obstetrics and Gynaecology, AOR San Carlo, Potenza, Italy., Cannone FG; Department of Obstetrics and Gynaecology, ARNAS Garibaldi Catania, Catania, Italy., Ettore G; Department of Obstetrics and Gynaecology, ARNAS Garibaldi Catania, Catania, Italy., Puppo A; Department of Obstetrics and Gynaecology, ASO Santa Croce e Carle, Cuneo, Italy., Borghese M; Department of Obstetrics and Gynaecology, ASO Santa Croce e Carle, Cuneo, Italy., Martinelli C; Unit of Gynecology and Obstetrics, Department of Human Pathology in Adulthood and Childhood 'G. Barresi', University Hospital G. Martino, University of Messina, Messina, Italy., Muzii L; Department of Maternal and Child Health and Urological Sciences, Sapienza University of Rome, Policlinico Umberto I, Rome, Italy., Di Donato V; Department of Maternal and Child Health and Urological Sciences, Sapienza University of Rome, Policlinico Umberto I, Rome, Italy., Driul L; Department of Maternal and Child Health, University-Hospital of Udine, Udine, Italy., Restaino S; Department of Maternal and Child Health, University-Hospital of Udine, Udine, Italy., Bergamini A; Department of Obstetrics and Gynaecology, IRCCS San Raffaele Hospital, Milan, Italy., Candotti G; Department of Obstetrics and Gynaecology, IRCCS San Raffaele Hospital, Milan, Italy., Bocciolone L; Department of Obstetrics and Gynaecology, IRCCS San Raffaele Hospital, Milan, Italy., Plotti F; Department of Obstetrics and Gynecology, Campus Bio-Medico University of Rome, Rome, Italy., Angioli R; Department of Obstetrics and Gynecology, Campus Bio-Medico University of Rome, Rome, Italy., Mantovani G; Department of Obstetrics and Gynecology, Gynecology Oncology and Minimally-Invasive Pelvic Surgery, International School of Surgical Anatomy, Sacred Heart Hospital Negrar, Verona, Italy., Ceccaroni M; Department of Obstetrics and Gynecology, Gynecology Oncology and Minimally-Invasive Pelvic Surgery, International School of Surgical Anatomy, Sacred Heart Hospital Negrar, Verona, Italy., Cassani C; Department of Obstetrics and Gynecology, IRCCS Foundation Policlinico San Matteo and University of Pavia, Pavia, Italy., Dominoni M; Department of Obstetrics and Gynecology, IRCCS Foundation Policlinico San Matteo and University of Pavia, Pavia, Italy., Giambanco L; Department of Obstetrics and Gynecology, S. Antonio Abate Hospital, Trapani, Italy and Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties (PROMISE), University of Palermo, Palermo, Italy., Amodeo S; Department of Obstetrics and Gynecology, S. Antonio Abate Hospital, Trapani, Italy and Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties (PROMISE), University of Palermo, Palermo, Italy., Leo L; Departments of Gynecology & Obstetrics, Hopital Beauregard, AUSL Valleè d'Aoste, Aosta, Italy., Thomasset R; Departments of Gynecology & Obstetrics, Hopital Beauregard, AUSL Valleè d'Aoste, Aosta, Italy., Raimondo D; Division of Gynaecology and Human Reproduction Physiopathology, Department of Medical and Surgical Sciences (DIMEC), IRCCS Azienda Ospedaliero-Univeristaria di Bologna. S. Orsola Hospital, University of Bologna, Bologna, Italy., Seracchioli R; Division of Gynaecology and Human Reproduction Physiopathology, Department of Medical and Surgical Sciences (DIMEC), IRCCS Azienda Ospedaliero-Univeristaria di Bologna. S. Orsola Hospital, University of Bologna, Bologna, Italy., Malzoni M; Endoscopica Malzoni, Center for Advanced Endoscopic Gynecologic Surgery, Avellino, Italy., Gorlero F; Department of Obstetrics and Gynaecology, Ente Ospedaliero Ospedali Galliera, Genova, Italy., Di Luca M; Department of Obstetrics and Gynaecology, Ente Ospedaliero Ospedali Galliera, Genova, Italy., Busato E; Department of Obstetrics and Gynaecology, Ospedale di Treviso, Treviso, Italy., Kilzie S; Department of Obstetrics and Gynaecology, Ospedale di Treviso, Treviso, Italy., Dell'Acqua A; Gynaecology Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy., Scarfone G; Gynaecology Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy., Vercellini P; Gynaecology Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy., Petrillo M; Gynecologic and Obstetric Unit, Department of Medical, Surgical and Experimental Sciences, University of Sassari, Sassari, Italy., Dessole S; Gynecologic and Obstetric Unit, Department of Medical, Surgical and Experimental Sciences, University of Sassari, Sassari, Italy., Capobianco G; Gynecologic and Obstetric Unit, Department of Medical, Surgical and Experimental Sciences, University of Sassari, Sassari, Italy., Ciavattini A; Gynecologic Section, Department of Odontostomatologic and Specialized Clinical Sciences, Università Politecnica delle Marche, Ancona, Italy., Delli Carpini G; Gynecologic Section, Department of Odontostomatologic and Specialized Clinical Sciences, Università Politecnica delle Marche, Ancona, Italy., Giannella L; Gynecologic Section, Department of Odontostomatologic and Specialized Clinical Sciences, Università Politecnica delle Marche, Ancona, Italy., Mereu L; Gynecological Oncology Unit, Santa Chiara Hospital, Trento, Italy., Tateo S; Gynecological Oncology Unit, Santa Chiara Hospital, Trento, Italy., Sorbi F; Gynecology Unit, Careggi University Hospital, Department of Biomedical, Experimental and Clinical Sciences 'Mario Serio', University of Florence, Florence, Italy., Fambrini M; Gynecology Unit, Careggi University Hospital, Department of Biomedical, Experimental and Clinical Sciences 'Mario Serio', University of Florence, Florence, Italy., Cicogna S; Department of Obstetrics and Gynaecology, Institute for Maternal and Child Health, IRCCS 'Burlo Garofolo', Trieste, Italy., Romano F; Department of Obstetrics and Gynaecology, Institute for Maternal and Child Health, IRCCS 'Burlo Garofolo', Trieste, Italy., Ricci G; Department of Obstetrics and Gynaecology, Institute for Maternal and Child Health, IRCCS 'Burlo Garofolo', Trieste, Italy.; Department of Medicine, Surgery and Health Sciences, University of Trieste, Trieste, Italy., Trojano G; Department of Obstetrics and Gynaecology, Madonna delle Grazie Hospital ASM, Matera, Italy., Consonni R; Gynecology Unit, Ospedale Valduce, Como, Italy., Cantaluppi S; Gynecology Unit, Ospedale Valduce, Como, Italy., Lippolis A; Unit of Obstetrics and Gynaecology, Valle D'Itra Hospital, Martina Franca, Taranto, Italy., Tinelli R; Unit of Obstetrics and Gynaecology, Valle D'Itra Hospital, Martina Franca, Taranto, Italy., D'Ippolito G; Unit of Obstetrics and Gynecology, Azienda Unità Sanitaria Locale - IRCCS, Reggio Emilia, Italy., Aguzzoli L; Unit of Obstetrics and Gynecology, Azienda Unità Sanitaria Locale - IRCCS, Reggio Emilia, Italy., Mandato VD; Unit of Obstetrics and Gynecology, Azienda Unità Sanitaria Locale - IRCCS, Reggio Emilia, Italy., Palomba S; Unit of Obstetrics and Gynecology, GOM of Reggio Calabria & Magna Grcia University of Catanzaro, Catanzaro, Italy., Calandra D; Unit of Obstetrics and Gynecology, University G. D'Annunzio of Chieti, Pescara, Italy., Rosati M; Unit of Obstetrics and Gynecology, University G. D'Annunzio of Chieti, Pescara, Italy.; Unit of Obstetrics and Gynecology, Santo Spirito Hospital, Pescara, Italy., Gallo C; Unit of Obstetrics and Gynecology, Università 'Magna Graecia' di Catanzaro - AO 'Pugliese - Ciaccio' Catanzaro, Italy., Surico D; Unit of Obstetrics and Gynecology, University of Eastern Piedmont, Novara, Italy., Remorgida V; Unit of Obstetrics and Gynecology, University of Eastern Piedmont, Novara, Italy., Ruscitto F; Gynecology Unit, Ospedale Valduce, Como - ASST Lariana, S. Anna, Como, Italy., Beretta P; Gynecology Unit, Ospedale Valduce, Como - ASST Lariana, S. Anna, Como, Italy., Benedetti Panici P; Department of Maternal and Child Health and Urological Sciences, Sapienza University of Rome, Policlinico Umberto I, Rome, Italy., Raspagliesi F; Gynecologic Oncology Unit, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Milan, Italy.

Publikováno v: Journal of gynecologic oncology [J Gynecol Oncol] 2022 Jan; Vol. 33 (1), pp. e10. Date of Electronic Publication: 2021 Nov 12.

p63 orchestrates serine and one carbon metabolism enzymes expression in head and neck cancer.

Autor: Cappello, Angela^1,2 (AUTHOR), Tosetti, Giulia¹ (AUTHOR), Smirnov, Artem^1,3 (AUTHOR), Ganini, Carlo^2,4 (AUTHOR), Yang, Xue^1,5,6 (AUTHOR), Shi, Yufang⁷ (AUTHOR), Wang, Ying⁸ (AUTHOR), Melino, Gerry¹ (AUTHOR), Bernassola, Francesca¹ (AUTHOR), Candi, Eleonora^1,3 (AUTHOR) candi@uniroma2.it

Publikováno v: Biology Direct. 11/9/2023, Vol. 18 Issue 1, p1-12. 12p.

Gene expression in organoids: an expanding horizon.

Autor: Smirnov, Artem¹ (AUTHOR), Melino, Gerry¹ (AUTHOR), Candi, Eleonora^1,2 (AUTHOR) candi@uniroma2.it

Publikováno v: Biology Direct. 3/25/2023, Vol. 18 Issue 1, p1-12. 12p.