Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Ruri Ishino"'
Autor:
Robert G. Roeder, Chihiro Kaminaga, Kasumi Oda, Norinaga Urahama, Haruka Fujita, Asami Kawai, Natsumi Hasegawa, Keiji Matsui, Ruri Ishino, Mitsuhiro Ito, Shumpei Mizuta, Azusa Fujita, Tomoya Minami
Publikováno v:
Genes to Cells. 19:28-51
The MED1 subunit of the Mediator transcriptional coregulator complex coactivates GATA1 and induces erythropoiesis. Here, we show the dual mechanism of GATA1- and MED1-mediated transcription. MED1 expression levels in K562 erythroleukemia cells parall
Autor:
Norinaga Urahama, Robert G. Roeder, Shumpei Mizuta, Ruri Ishino, Keiji Matsui, Kasumi Oda, Natsumi Hasegawa, Mitsuhiro Ito
Publikováno v:
Biochemical and Biophysical Research Communications. 440:184-189
The MED1 subunit of the Mediator transcriptional coregulator complex is a nuclear receptor-specific coactivator. A negative feedback mechanism of thyroid-stimulating hormone (TSH, or thyrotropin) expression in the thyrotroph in the presence of triiod
Autor:
Nobuhide Hayashi, Ichiro Morioka, Itsuko Sato, Ruri Ishino, Jun Saegusa, Kayo Osawa, Kazumoto Iijima, Sota Iwatani, Noriko Fukuzumi
Publikováno v:
Scientific Reports
Procalcitonin (PCT) levels are elevated early after birth in newborn infants; however, the physiological features and reference of serum PCT concentrations have not been fully studied in preterm infants. The aims of the current study were to establis
Autor:
Robert G. Roeder, Toru Kondo, Osamu Horie, Hiroshi Matsuoka, Norinaga Urahama, Kana Inoue, Natsumi Hasegawa, Akiko Sumitomo, Ruri Ishino, Kenji Yonezawa, Mitsuhiro Ito
Publikováno v:
Molecular and Cellular Biology. 30:4818-4827
MED1/TRAP220, a subunit of the transcriptional Mediator/TRAP complex, is crucial for various biological events through its interaction with distinct activators, such as nuclear receptors and GATA family activators. In hematopoiesis, MED1 plays a pivo
Autor:
Shigetaka Asano, Kaori Minami, Mami Nagai, Keiji Matsui, Natsumi Hasegawa, Satowa Tanaka, Ruri Ishino, Robert G. Roeder, Mitsuhiro Ito
Publikováno v:
Biochemical and biophysical research communications. 440(1)
FGF1 and FGF2 support hematopoietic stem and progenitor cells (HSPCs) under stress conditions. In this study, we show that fibroblast growth factor (FGF7) may be a novel niche factor for HSPC support and leukemic growth. FGF7 expression was attenuate
Autor:
Junko Nose, Norinaga Urahama, Shumpei Mizuta, Robert G. Roeder, Azusa Fujita, Kana Inoue, Shingo Kamoshida, Keiji Matsui, Ruri Ishino, Nami Aritome, Toru Mukohara, Natsumi Hasegawa, Mitsuhiro Ito, Akiko Sumitomo
The Mediator subunit MED1 is essential for mammary gland development and lactation, whose contribution through direct interaction with estrogen receptors (ERs) is restricted to involvement in pubertal mammary gland development and luminal cell differ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1e40b36aacbb070e5132d1ced60ae6b
https://europepmc.org/articles/PMC3318591/
https://europepmc.org/articles/PMC3318591/
Autor:
Norinaga Urahama, Shumpei Mizuta, Haruka Fujita, Mitsuhiro Ito, Akiko Sumitomo, Tomoya Minami, Ruri Ishino, Keiji Matsui, Kasumi Oda, Chihiro Kaminaga
Publikováno v:
Blood. 118:1302-1302
Abstract 1302 The mammalian multi-protein complex Mediator, originally identified by ourselves as a nuclear receptor-specific coactivator complex, is a phylogenetically-conserved subcomplex of the RNA polymerase II holoenzyme and serves as an end-poi
Autor:
Tomoya Minami, Mitsuhiro Ito, Ruri Ishino, Chihiro Kaminaga, Kasumi Oda, Shumpei Mizuta, Keiji Matsui, Akiko Sumitomo
Publikováno v:
Blood. 116:3865-3865
Abstract 3865 Mediator/TRAP complex, a master transcriptional coregulator, constitutes a subcomplex of RNA polymerase II holoenzyme, and integrates a wide variety of intracellular signals through specific interactions of activators with specific Medi
Autor:
Naohiko Seki, Kana Inoue, Ruri Ishino, Akiko Sumitomo, Chisa Iwasaki, Kenji Yonezawa, Osamu Horie, Natsumi Hasegawa, Norinaga Urahama, Mitsuhiro Ito
Publikováno v:
Blood. 114:250-250
Abstract 250 The multi-protein complex TRAP/Mediator is a subcomplex of RNA polymerase II holoenzyme. Mediator acts as the end-point integrator of a variety of activators and intracellular signaling, and conveys these signals to the general transcrip