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pro vyhledávání: '"Ruqaia Abbas"'
Autor:
Ruqaia Abbas, Sarit Larisch
Publikováno v:
Cells, Vol 10, Iss 12, p 3465 (2021)
Apoptosis is a cell suicide process that is essential for development, tissue homeostasis and human health. Impaired apoptosis is associated with a variety of human diseases, including neurodegenerative disorders, autoimmunity and cancer. As the leve
Externí odkaz:
https://doaj.org/article/6c1e16cc959244e29db0a849a866c6bd
Autor:
Ruqaia Abbas, Sarit Larisch
Publikováno v:
Cells, Vol 9, Iss 3, p 663 (2020)
Inhibitors of apoptosis (IAPs) are a family of proteins that regulate cell death and inflammation. XIAP (X-linked IAP) is the only family member that suppresses apoptosis by directly binding to and inhibiting caspases. On the other hand, cIAPs suppre
Externí odkaz:
https://doaj.org/article/138fecf706c04b3ea0c78b772b9ab0c6
Autor:
Nir Kfir, Dana Mamriev, Dalit Barkan, David W. Sheppard, Sarit Larisch, Juliana Kagan, Ruqaia Abbas, Alastair Donald, Franca-Maria Klingler, Keren Weidenfeld
Publikováno v:
Cell Death & Disease
Cell Death and Disease, Vol 11, Iss 6, Pp 1-16 (2020)
Cell Death and Disease, Vol 11, Iss 6, Pp 1-16 (2020)
Many human cancers over-express B cell lymphoma 2 (Bcl-2) or X-linked inhibitor of apoptosis (IAP) proteins to evade cell death. The pro-apoptotic ARTS (Sept4_i2) protein binds directly to both Bcl-2 and XIAP and promotes apoptosis by stimulating the