Phase I/II clinical trial of the targeted chemotherapeutic drug, folate-tubulysin, in dogs with naturally-occurring invasive urothelial carcinoma.

Autor: Szigetvari NM; Department of Veterinary Clinical Sciences, Purdue University, West Lafayette, IN, USA., Dhawan D; Department of Veterinary Clinical Sciences, Purdue University, West Lafayette, IN, USA., Ramos-Vara JA; Department of Comparative Pathobiology, Purdue University, West Lafayette, IN, USA., Leamon CP; Endocyte Inc., West Lafayette, IN, USA., Klein PJ; Endocyte Inc., West Lafayette, IN, USA., Ruple AA; Department of Comparative Pathobiology, Purdue University, West Lafayette, IN, USA., Heng HG; Department of Veterinary Clinical Sciences, Purdue University, West Lafayette, IN, USA., Pugh MR; Endocyte Inc., West Lafayette, IN, USA., Rao S; Endocyte Inc., West Lafayette, IN, USA., Vlahov IR; Endocyte Inc., West Lafayette, IN, USA., Deshuillers PL; Department of Comparative Pathobiology, Purdue University, West Lafayette, IN, USA., Low PS; Department of Chemistry, Purdue University, West Lafayette, IN, USA.; Purdue University Center for Cancer Research, West Lafayette, IN, USA., Fourez LM; Department of Veterinary Clinical Sciences, Purdue University, West Lafayette, IN, USA., Cournoyer AM; Department of Veterinary Clinical Sciences, Purdue University, West Lafayette, IN, USA., Knapp DW; Department of Veterinary Clinical Sciences, Purdue University, West Lafayette, IN, USA.; Purdue University Center for Cancer Research, West Lafayette, IN, USA.

Publikováno v: Oncotarget [Oncotarget] 2018 Dec 11; Vol. 9 (97), pp. 37042-37053. Date of Electronic Publication: 2018 Dec 11 (Print Publication: 2018).