Zobrazeno 1 - 10
of 313
pro vyhledávání: '"Rupert Vessey"'
Autor:
Bayer, Max (AUTHOR), Masson, Gabrielle (AUTHOR)
Publikováno v:
FierceBiotech. 7/14/2023, pN.PAG-N.PAG. 1p.
Autor:
Courtney G. Havens, Correa Matthew D, Rama K. Narla, Frans Baculi, Kercher Timothy S, Thomas O. Daniel, Roy L. Harris, Brian E. Cathers, Matt Alexander, Mehran F. Moghaddam, Grant Virginia Heather Sharron, Veronique Plantevin, James Carmichael, Katalin Ebinger, Antonia Lopez-Girona, Gody Khambatta, Derek Mendy, Lawrence G Hamann, Joshua Hansen, Katerina Leftheris, Brandon Wade Whitefield, Joseph Piccotti, Nagy Mark A, Rupert Vessey, Yang Tang, Laurie LeBrun, Jim Leisten, Dehua Huang
Publikováno v:
Journal of Medicinal Chemistry. 63:6648-6676
Many patients with multiple myeloma (MM) initially respond to treatment with modern combination regimens including immunomodulatory agents (lenalidomide and pomalidomide) and proteasome inhibitors. However, some patients lack an initial response to t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b7c02cb54b83623d7f5d29645738bcd
https://doi.org/10.1021/acs.jmedchem.9b01928
https://doi.org/10.1021/acs.jmedchem.9b01928
Autor:
Ke Hao, Yohan Bossé, David C. Nickle, Peter D. Paré, Dirkje S. Postma, Michel Laviolette, Andrew Sandford, Tillie L. Hackett, Denise Daley, James C. Hogg, W. Mark Elliott, Christian Couture, Maxime Lamontagne, Corry-Anke Brandsma, Maarten van den Berge, Gerard Koppelman, Alise S. Reicin, Donald W. Nicholson, Vladislav Malkov, Jonathan M. Derry, Christine Suver, Jeffrey A. Tsou, Amit Kulkarni, Chunsheng Zhang, Rupert Vessey, Greg J. Opiteck, Sean P. Curtis, Wim Timens, Don D. Sin
Publikováno v:
PLoS Genetics, Vol 8, Iss 12 (2012)
Externí odkaz:
https://doaj.org/article/1089411155cd4ffca18d2a904a27d910
Autor:
Ke Hao, Yohan Bossé, David C Nickle, Peter D Paré, Dirkje S Postma, Michel Laviolette, Andrew Sandford, Tillie L Hackett, Denise Daley, James C Hogg, W Mark Elliott, Christian Couture, Maxime Lamontagne, Corry-Anke Brandsma, Maarten van den Berge, Gerard Koppelman, Alise S Reicin, Donald W Nicholson, Vladislav Malkov, Jonathan M Derry, Christine Suver, Jeffrey A Tsou, Amit Kulkarni, Chunsheng Zhang, Rupert Vessey, Greg J Opiteck, Sean P Curtis, Wim Timens, Don D Sin
Publikováno v:
PLoS Genetics, Vol 8, Iss 11, p e1003029 (2012)
Genome-wide association studies (GWAS) have identified loci reproducibly associated with pulmonary diseases; however, the molecular mechanism underlying these associations are largely unknown. The objectives of this study were to discover genetic var
Externí odkaz:
https://doaj.org/article/6259f2c8ff324226a4a1dc7021fe8b98
Autor:
Mariko Riley, Katie Stamp, Xinde Zheng, Yan Ren, Kate Blease, Chin-Chun Lu, Julia Hui, Lawrence G Hamann, Philip P Chamberlain, Gang Lu, Polat Abdubek, Mary E Matyskiela, Gondi Kumar, Maria Wang, Wei Fang, Aaron Carpenter, Thomas Clayton, Clifton Drew, Suzana Couto, Chung-Wein Lee, Mark Rolfe, Rupert Vessey, James Hartke
Publikováno v:
Nature Chemical Biology. 14:981-987
Targeted protein degradation via small-molecule modulation of cereblon offers vast potential for the development of new therapeutics. Cereblon-binding therapeutics carry the safety risks of thalidomide, which caused an epidemic of severe birth defect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29f5299ace6c6c8aa0af7dbee0692fbc
https://doi.org/10.1038/s41589-018-0129-x
https://doi.org/10.1038/s41589-018-0129-x