Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Rupert Purchase"'
Autor:
Rupert Purchase, Frances M. Platt, Zilin Yu, Karin Tuschl, Julia Baguña Torres, Philip J. Blower, David Smith, John Spencer, Jayanta Bordoloi, Claire Friedemann Smith, Kavitha Sunassee, Oscar C. W. Chen
Publikováno v:
Baguña Torres, J, Yu, Z, Bordoloi, J, Sunassee, K, Smith, D, Smith, C, Chen, O, Purchase, R, Tuschl, K, Spencer, J, Platt, F & Blower, P J 2019, ' Imaging of changes in copper trafficking and redistribution in a mouse model of Niemann-Pick C disease using positron emission tomography ', Biometals, vol. 32, no. 2, pp. 293-306 . https://doi.org/10.1007/s10534-019-00185-5
Biometals
Biometals
Niemann-Pick C disease (NPC) is an autosomal recessive lysosomal storage disorder resulting from mutations in the NPC1 (95% of cases) or NPC2 genes. Disturbance of copper homeostasis has been reported in NPC1 disease.In this study we have used whole-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a33be369925a7b650802dc6c853bc83d
https://doi.org/10.1007/s10534-019-00185-5
https://doi.org/10.1007/s10534-019-00185-5
Autor:
Cynthia Abou Zeid, Aftab Ala, Michelle Angela Camarata, Anna Członkowska, Anil Dhawan, Hans Peter Dienes, James S. Dooley, Petr Dusek, Peter Ferenci, Si Houn Hahn, Roderick H.J. Houwen, Dominik Huster, Samuel Jayakanthan, Stephen G. Kaler, Eirini Kyrana, Josef Lichtmannegger, Tomasz Litwin, Svetlana Lutsenko, Courtney McCann, Peter Ott, Hannah Pierson, Aurélia Poujois, Rupert Purchase, Daphne Robakis, Eve A. Roberts, Christian Rupp, Thomas Damgaard Sandahl, Michael L. Schilsky, Peter Schirmacher, Palittiya Sintusek, Ana Vives-Rodriguez, Karl Heinz Weiss, France Woimant, Paula C. Zimbrean, Hans Zischka
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::89dcb397d6f94bf161de14ebbb21a27f
https://doi.org/10.1016/b978-0-12-811077-5.09992-8
https://doi.org/10.1016/b978-0-12-811077-5.09992-8
Autor:
Caroline Cooper, Rupert Purchase
Launched in 1995 as a companion to the Dictionary of Organic Compounds, the Organic Chemist's Desk Reference has been essential reading for laboratory chemists who need a succinct guide to the ‘nuts and bolts'of organic chemistry — the literature
Autor:
Rupert Purchase, James R. Hanson
Publikováno v:
Science Progress. 98:212-218
This review describes the life of Sir John Cornforth AC CBE FRS, who was awarded the Nobel Prize for Chemistry in 1975. It covers his early life in Australia, his work in Oxford, the National Institute for Medical Research, the Milstead Laboratory of
Autor:
Caroline Cooper, Rupert Purchase
Publikováno v:
Organic Chemist’s Desk Reference
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::676f0b54761fb588bb4df5e94d91857f
https://doi.org/10.1201/9781315120768-15
https://doi.org/10.1201/9781315120768-15
Autor:
Caroline Cooper, Rupert Purchase
Publikováno v:
Organic Chemist’s Desk Reference
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e59b7a27291e19ca35e98a246b3b86c3
https://doi.org/10.1201/9781315120768-16
https://doi.org/10.1201/9781315120768-16
Written by a group of experts affiliated with the prestigious Dictionary of Natural Products, this book provides a concise overview of the key structural types of natural products and their interrelationship. A structurally diverse group, ranging fro
Autor:
Rupert Purchase
Publikováno v:
Science Progress. 96:19-32
Wilson's disease is a rare autosomal recessive disease characterised by the deposition of copper in the brain, liver, cornea, and other organs. The overload of copper inevitably leads to progressive liver and neurological dysfunction. Copper overload