What Factors Determine Treatment Outcome in Aneurysmal Subarachnoid Hemorrhage in the Modern Era? A Post Hoc STASH Analysis

Autor: Mario Teo, Mathew R. Guilfoyle, Carole Turner, Peter J. Kirkpatrick, Carole L. Turner, Gordon D. Murray, Peter J. Hutchinson, Graham Teasdale, A. David Mendelow, Keith Muir, Martin Smith, Peter McCabe, Jeremy Pearson, Gary Ford, Andrew Vail, Andrew King, Pippa Tyrrell, Hugh Richards, Simon Bond, Christopher Smith, Elizabeth Warburton, Ming Tseng, Diederik Bulters, Martina Brown, Giles Critchley, Gavin Spurling, Jane Gaylard, Mohsen Javadpour, Paul Eldridge, Lorna Murray, Richard Nelson, Ros Taylor, Sarah Hierons, Bianca Tobin, Kelley Storey, Daniel Walsh, Bejal Mistry, John Aeron-Thomas, Corina Puppo, Mario Papadopoulos, Laura Montague, Peter Gan, Graham Flint, Jennie Hurley, Elizabeth Ronne, Inger Stjernling, Ernest Wang, Ei Leen Cheng, Jing Li Lai, Stuart Ross, Ruth Bellfield, Linetty Mandizvidza, Peter Whitfield, Nicola Persad, Nigel Suttner, Kate McGuigan, Linda Cloughley, Hiren Patel, Andrea Ingham, Kellymarie Shaw, Raghu Vindlacheruvu, Julian Millo, Orlando Warner, Rachel Teal, Francis Bernard, Carol Sirois, Shaban Joshi, Sheila Nyabadza, Joan Grieve, Neil Kitchen, Vanessa Bassan, Philip Rayson, Alexander Zeitlin, Max Findlay, Leeca Sonnema, Brenda Poworoznik, Juan Quintero, Sam Eljamel, Frank Rasulo, Ivan Ng, Bruce Mathew, Jill Grieg, Ricardo Hanel, Alexa Richie, Ian Fleetwood, Elizabeth Reardon-White, Ginger Hampton, Stephen Lewis, Lynn Miralia, Howard Brydon, Holly Maguire, Umang Patel, Helen Sanderson, Kathryn Birchall, Pauline Bayliss, Kevin O'Neill, Tina Sachs, Rupert Kett-White, Leanne Quinn

Background The management of aneurysmal subarachnoid hemorrhage (aSAH) has changed dramatically in the last few decades with the publication of a few major studies, including ISAT (International Subarachnoid Aneurysm Trial, the International Cooperat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::880d7d35873554bd6cb87b4d3585a885
http://hdl.handle.net/11379/499563

Measurement of brain tissue oxygenation performed using positron emission tomography scanning to validate a novel monitoring method

Autor: Peter J. Kirkpatrick, Dot A Parry, Pawan S. Minhas, John D. Pickard, Peter J. Hutchinson, Steve P. M. J. Downey, Arun K. Gupta, Franklin I. Aigbirhio, Tim D. Fryer, Pippa G. Al-Rawi, Julian C Mathews, John A. Clark, Rupert Kett-White, David K. Menon

Publikováno v: Journal of Neurosurgery. 96:263-268

Object. The benefits of measuring cerebral oxygenation in patients with brain injury are well accepted; however, jugular bulb oximetry, which is currently the most popular monitoring technique used has several shortcomings. The goal of this study was

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fea0c00c0287023f754818eda23d6362
https://doi.org/10.3171/jns.2002.96.2.0263

Sprouting of peripherally regenerating primary sensory neurones in the adult central nervous system

Autor: Rupert Kett‐White, Stephen B. McMahon

Publikováno v: The Journal of Comparative Neurology. 304:307-315

We have studied the ability of primary afferent neurones to proliferate within the grey matter of the dorsal horn following the degeneration of other, nearby, afferent fibres. The peripheral branches of primary afferents have the capacity to regenera

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab7b680f38a1f7cd339552e90b224851
https://doi.org/10.1002/cne.903040211

Cerebral oxygen and microdialysis monitoring during aneurysm surgery: effects of blood pressure, cerebrospinal fluid drainage, and temporary clipping on infarction

Autor: Pippa G. Al-Rawi, Peter J. Kirkpatrick, Peter J. Hutchinson, Rupert Kett-White, Marek Czosnyka, John D. Pickard, Arun K. Gupta

Publikováno v: Journal of neurosurgery. 96(6)

Object. The aim of this study was to investigate potential episodes of cerebral ischemia during surgery for large and complicated aneurysms, by examining the effects of arterial temporary clipping and the impact of confounding variables such as blood

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b696a3a6f43f0d626a5cd2fd2b402a08
https://pubmed.ncbi.nlm.nih.gov/12066900

Clinical Cerebral Microdialysis — Determining the True Extracellular Concentration

Autor: Rupert Kett-White, Pippa G. Al-Rawi, M. T. O’Connell, Peter J. Kirkpatrick, Peter J. Hutchinson, John D. Pickard, Arun K. Gupta

Publikováno v: Intracranial Pressure and Brain Biochemical Monitoring ISBN: 9783709173978

Current monitoring of the cerebral extracellular chemistry of neurosurgical patients using microdialysis does not provide the true extracellular concentration because full equilibration across the membrane is not achieved. By varying the flow rate an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1516850619301bd60beea4c3a904bad2
https://doi.org/10.1007/978-3-7091-6738-0_91