Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Rupendra, Shrestha"'
Publikováno v:
BMC Neurology, Vol 24, Iss 1, Pp 1-9 (2024)
Abstract Background Cascade testing can offer improved surveillance and timely introduction of clinical management for the at-risk biological relatives. Data on cascade testing and costs in mitochondrial diseases are lacking. To address this gap, we
Externí odkaz:
https://doaj.org/article/2cff59b63a47472e84f5a9a26dbc5cae
Autor:
Rajasekaran Subbarayan, Dhasarathdev Srinivasan, Salman Sadullah Usmani, Dinesh Murugan Girija, Shoeb Ikhlas, Nityanand Srivastav, Ranjith Balakrishnan, Rupendra Shrestha, Ankush Chauhan
Publikováno v:
Platelets, Vol 35, Iss 1 (2024)
The purpose of this study is to investigate the molecular interactions and potential therapeutic uses of Eltrombopag (EPAG), a small molecule that activates the cMPL receptor. EPAG has been found to be effective in increasing platelet levels and alle
Externí odkaz:
https://doaj.org/article/71894afd5bf346fabde0e21c91872dce
Publikováno v:
BMJ Neurology Open, Vol 6, Iss 2 (2024)
Background Mitochondrial diseases often follow a chronic, multimorbid disease course in adults. Like other chronic conditions, mitochondrial diseases present a challenge to public and community health models and patients are potentially at higher ris
Externí odkaz:
https://doaj.org/article/f0e5da252a6e4db69b468dcca18dfc2b
Autor:
Rupendra Shrestha, Lennert Veerman, Megan Passey, Deborah J Schofield, Robert Tanton, Simon J Kelly, Katherine Lim
Publikováno v:
BMJ Open, Vol 14, Iss 5 (2024)
Objectives To estimate the economic burden of informal caregivers not in the labour force (NILF) due to caring for a person with arthritis in Australia, with projections of these costs from 2015 to 2030.Design Static microsimulation modelling using n
Externí odkaz:
https://doaj.org/article/1bf81007a7c9476f916cf7b01eb2e539
Publikováno v:
BMJ Neurology Open, Vol 6, Iss 1 (2024)
Background Mitochondrial diseases in adults are generally chronic conditions with a wide spectrum of severity contributing to disease burden and healthcare resource utilisation. Data on healthcare resource utilisation in mitochondrial diseases are li
Externí odkaz:
https://doaj.org/article/68828e5552b5478cafe7495d2c3f5575
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 18, Iss 1, Pp 1-9 (2023)
Abstract Background and objectives Mitochondrial diseases present as multi-system disorders requiring a comprehensive multidisciplinary approach. The data on healthcare resource utilization associated with mitochondrial diseases and the clinical driv
Externí odkaz:
https://doaj.org/article/322e59d99d3d4f91a32b4fbf7c85d360
Publikováno v:
eLife, Vol 12 (2023)
The telencephalon and eye in mammals are originated from adjacent fields at the anterior neural plate. Morphogenesis of these fields generates telencephalon, optic-stalk, optic-disc, and neuroretina along a spatial axis. How these telencephalic and o
Externí odkaz:
https://doaj.org/article/6e69f24188d94f43b2caa8f124efa54c
Autor:
Deborah Schofield, PhD, Joshua Kraindler, MSc, Owen Tan, MComm, Rupendra Shrestha, PhD, Diana Jelovic, BAppSci, Sarah West, MBMSc, Alan Ma, PhD, FRACP, John Grigg, MD, FRANZCO, Robyn V. Jamieson, PhD, FRACP
Publikováno v:
Ophthalmology Science, Vol 2, Iss 1, Pp 100106- (2022)
Purpose: To evaluate the impact of inherited retinal diseases (IRDs) on quality of life (QoL) using multiattributable health utilities derived from primary patient data. Design: Cross-sectional observational study. Participants: Seventy adult patient
Externí odkaz:
https://doaj.org/article/c2a99d823c954ffebcbd8e1d469c3a4d
Publikováno v:
Tzu-Chi Medical Journal, Vol 32, Iss 2, Pp 101-112 (2020)
The visual impairment associated with inherited retinal degeneration and age-related degeneration of photoreceptors is causing substantial challenges in finding effective therapies. However, induced pluripotent stem cell (iPSC)-derived therapeutic ce
Externí odkaz:
https://doaj.org/article/da2137f9723b4baea130c84be7d482bc
Publikováno v:
Journal of Nepal Medical Association, Vol 59, Iss 239 (2021)
While there is absolutely no evidence to ensure recovered patients are either likely or unlikely to get reinfected. But studies in non-human primates indicate that reinfection of recovered patients is highly unlikely. It is also clear that primary im
Externí odkaz:
https://doaj.org/article/e90d9e7bddce4b53aaed9889cb387e32