Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Rupen Desai"'
Autor:
Jinyun Yuan, Lu Xu, Chih-Yen Chien, Yaoheng Yang, Yimei Yue, Siaka Fadera, Andrew H. Stark, Katherine E. Schwetye, Arash Nazeri, Rupen Desai, Umeshkumar Athiraman, Aadel A. Chaudhuri, Hong Chen, Eric C. Leuthardt
Publikováno v:
npj Precision Oncology, Vol 7, Iss 1, Pp 1-11 (2023)
Abstract Sonobiopsy is an emerging technology that combines focused ultrasound (FUS) with microbubbles to enrich circulating brain disease-specific biomarkers for noninvasive molecular diagnosis of brain diseases. Here, we report the first-in-human p
Externí odkaz:
https://doaj.org/article/330caae5269d4fd09e7a4eee2306b6d3
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 11, p 5877 (2024)
Chordomas, arising from notochord remnants, are rare neoplasms with aggressive growth patterns despite their histologically low-grade nature. This review explores their embryological origins, molecular markers like brachyury, and genetic alterations
Externí odkaz:
https://doaj.org/article/e8a3e5e50fe34b6fbe07bd39d226514c
Surgery for Pituitary Tumor Apoplexy Is Associated with Rapid Headache and Cranial Nerve Improvement
Autor:
Kevin A. Cross, Rupen Desai, Ananth Vellimana, Yupeng Liu, Keith Rich, Gregory Zipfel, Ralph Dacey, Michael Chicoine, Cristine Klatt-Cromwell, Jonathan McJunkin, Patrik Pipkorn, John S. Schneider, Julie Silverstein, Albert H. Kim
Publikováno v:
Current Oncology, Vol 29, Iss 7, Pp 4914-4922 (2022)
Pituitary tumor apoplexy (PTA) classically comprises sudden-onset headache, loss of vision, ophthalmoparesis, and decreased consciousness. It typically results from hemorrhage and/or infarction within a pituitary adenoma. Presentation is heterologous
Externí odkaz:
https://doaj.org/article/292028a8b2ea49dfb42bcba8c5bf645c
Autor:
Anthony Z. Wang, Jay A. Bowman-Kirigin, Rupen Desai, Liang-I Kang, Pujan R. Patel, Bhuvic Patel, Saad M. Khan, Diane Bender, M. Caleb Marlin, Jingxian Liu, Joshua W. Osbun, Eric C. Leuthardt, Michael R. Chicoine, Ralph G. Dacey, Gregory J. Zipfel, Albert H. Kim, David G. DeNardo, Allegra A. Petti, Gavin P. Dunn
Publikováno v:
Genome Medicine, Vol 14, Iss 1, Pp 1-25 (2022)
Abstract Background Recent investigations of the meninges have highlighted the importance of the dura layer in central nervous system immune surveillance beyond a purely structural role. However, our understanding of the meninges largely stems from t
Externí odkaz:
https://doaj.org/article/c17233161de54fbe91f8411660beec7a
Autor:
David M Kranz, Michael J White, Mao Li, Maximilian O Schaettler, Rupen Desai, Anthony Z Wang, Alexandra J Livingstone, Dale K Kobayashi, Andrew T Coxon, Jay A Bowman-Kirigin, Connor J Liu, Diane E Bender, Tanner M Johanns, Gavin P Dunn
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 2 (2023)
Background Adoptive cellular therapies with chimeric antigen receptor T cells have revolutionized the treatment of some malignancies but have shown limited efficacy in solid tumors such as glioblastoma and face a scarcity of safe therapeutic targets.
Externí odkaz:
https://doaj.org/article/67ba15afade74b8a9caa7534c5ef5ce0
Autor:
Andrew Coxon, Rupen Desai, Tanner M Johanns, Gavin P Dunn, Saad M Khan, Alexandra Livingstone, Allegra Petti
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 12 (2022)
Background Glioblastoma is a fatal disease despite aggressive multimodal therapy. PD-1 blockade, a therapy that reinvigorates hypofunctional exhausted CD8 T cells (Tex) in many malignancies, has not shown efficacy in glioblastoma. Loss of CD4 T cells
Externí odkaz:
https://doaj.org/article/e57e0b22c39e49c4bbbdfaaa8929a27b
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Externí odkaz:
https://doaj.org/article/8eb8d1bed78c4892ba4e01ff2b14e231
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Meningiomas are common primary central nervous system tumors derived from the meninges, with management most frequently entailing serial monitoring or a combination of surgery and/or radiation therapy. Although often considered benign lesions, mening
Externí odkaz:
https://doaj.org/article/7ff70eaa6e3e43e09e2f24d0cf3499c7
Autor:
Carter M. Suryadevara, Rupen Desai, Melissa L. Abel, Katherine A. Riccione, Kristen A. Batich, Steven H. Shen, Pakawat Chongsathidkiet, Patrick C. Gedeon, Aladine A. Elsamadicy, David J. Snyder, James E. Herndon, Patrick Healy, Gary E. Archer, Bryan D. Choi, Peter E. Fecci, John H. Sampson, Luis Sanchez-Perez
Publikováno v:
OncoImmunology, Vol 7, Iss 6 (2018)
Adoptive transfer of T cells expressing chimeric antigen receptors (CARs) is an effective immunotherapy for B-cell malignancies but has failed in some solid tumors clinically. Intracerebral tumors may pose challenges that are even more significant. I
Externí odkaz:
https://doaj.org/article/c3735e2fade249f4a634f5f92b5dfa6e
Autor:
Jay A. Bowman-Kirigin, Rupen Desai, Brian T. Saunders, Anthony Z. Wang, Maximilian O. Schaettler, Connor J. Liu, Alexandra J. Livingstone, Dale K. Kobayashi, Vivek Durai, Nicole M. Kretzer, Gregory J. Zipfel, Eric C. Leuthardt, Joshua W. Osbun, Michael R. Chicoine, Albert H. Kim, Kenneth M. Murphy, Tanner M. Johanns, Bernd H. Zinselmeyer, Gavin P. Dunn
Publikováno v:
Cancer Immunology Research. 11:20-37
The central nervous system (CNS) antigen-presenting cell (APC) that primes antitumor CD8+ T-cell responses remains undefined. Elsewhere in the body, the conventional dendritic cell 1 (cDC1) performs this role. However, steady-state brain parenchyma c