Zobrazeno 1 - 10
of 156
pro vyhledávání: '"Rupei Tang"'
Autor:
Lin Wang, Hao Shi, Yanan Fan, Tao Meng, Shidi Lou, Zhuo Wang, Jiaxing Zhang, Jihu Su, Ruochun Yin, Rupei Tang
Publikováno v:
Results in Engineering, Vol 21, Iss , Pp 101666- (2024)
Degradation of lignin, a natural macromolecule, by laccase via substrate radicals has been intensively studied. However, the interactions between laccase and DNA have not been thoroughly elucidated to date. In this report, we demonstrate that laccase
Externí odkaz:
https://doaj.org/article/2dcc7c56a8374136b35a231f85ab4a64
Autor:
Shi Wang, Yining Song, Jingge Ma, Xinyang Chen, Yuanhui Guan, Hui Peng, Guoqing Yan, Rupei Tang
Publikováno v:
Asian Journal of Pharmaceutical Sciences, Vol 17, Iss 6, Pp 880-891 (2022)
To achieve highly selective synergistic chemotherapy attractive for clinical translation, the precise polymeric nano-prodrugs (PPD-NPs) were successfully constructed via the facile crosslinking reaction between pH-sensitive poly(ortho ester)s and red
Externí odkaz:
https://doaj.org/article/e6f356aa4c4e4175a8f1908c718b2e12
Autor:
Xin Liu, Zhexiang Wang, Xiaodie Ren, Xinyang Chen, Jinjin Tao, Yuanhui Guan, Xuefeng Yang, Rupei Tang, Guoqing Yan
Publikováno v:
Asian Journal of Pharmaceutical Sciences, Vol 18, Iss 4, Pp 100832- (2023)
Currently, the dynamic erosive small molecule nano-prodrug is of great demand for oral chemotherapy, owing to its precise structure, high drug loading and improved oral bioavailability via overcoming various physiologic barriers in gastrointestinal t
Externí odkaz:
https://doaj.org/article/bd9a4553b4464ca781e06e45d4e246ba
Autor:
Ruochun Yin, Yiling Zhang, Liping Su, Dongdong Chen, Shidi Lou, Xuecai Luo, Lin Wang, Rupei Tang, Liang Zhang, Xiaohe Tian
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Trans-δ-viniferin (TVN), as a natural extract, is a resveratrol dimer with attractive biological activities, particularly its anti-tumor character. However, the mechanism of TVN interfering with cancerous proliferation has not been fully understood.
Externí odkaz:
https://doaj.org/article/dfd93d7da0904e82abe90230759184e1
Autor:
Xu Cheng, Dapeng Li, Jiaxi Xu, Bing Wei, Qin Fang, Longshun Yang, Yanbing Xue, Xin Wang, Rupei Tang
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 11, Pp 3595-3607 (2021)
Traditional chemotherapy exhibits a certain therapeutic effect toward malignant cancer, but easily induce tumor multidrug resistance (MDR), thereby resulting in the progress of tumor recurrence or metastasis. In this work, we deigned ternary hybrid n
Externí odkaz:
https://doaj.org/article/d5df5efdbff347129415b5f6fb84d986
Publikováno v:
Asian Journal of Pharmaceutical Sciences, Vol 16, Iss 6, Pp 762-771 (2021)
Carrier-free drug self-delivery systems consisting of amphiphilic drug-drug conjugate (ADDC) with well-defined structure and nanoscale features have drawn much attention in tumor drug delivery. Herein, we report a simple and effective strategy to pre
Externí odkaz:
https://doaj.org/article/36ffcfa293cb4d569b15eed57f94cfdd
Publikováno v:
Asian Journal of Pharmaceutical Sciences, Vol 16, Iss 3, Pp 363-373 (2021)
TPGS approved by FDA can be used as a P-gp inhibitor to effectively reverse multi-drug resistance (MDR) and as an anticancer agent for synergistic antitumor effects. However, the comparatively high critical micelle concentration (CMC), low drug loadi
Externí odkaz:
https://doaj.org/article/e13c2bdbbf004a6f88c6c34fb9200cba
Publikováno v:
Asian Journal of Pharmaceutical Sciences, Vol 15, Iss 6, Pp 728-738 (2020)
Although surface PEGylation of nanomedicines can decrease serum protein adsorption in vivo, it also blocks uptake by tumor cells. This dilemma could be overcome by employing detachably PEGylated strategy at tumoral extracellular microenvironment to a
Externí odkaz:
https://doaj.org/article/2ae362150e5f483087f05c9a3190d07f
Publikováno v:
Journal of Biomaterials Applications. 37:634-645
Herein, we combined a derivative of cisplatin (CP) and the chemosensitizer lonidamine (LND) to design an amphiphilic prodrug, in which the ratio of LND to cisplatin was fixed at 2:1. Diaminedichlorodihydroxyplatinum (DH-CP) is a hydrophilic cisplatin
Publikováno v:
Journal of Nanoparticle Research. 25