Zobrazeno 1 - 10 of 17 pro vyhledávání: '"Rupa Idate"'
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Akademický článek
Integrated analysis of canine soft tissue sarcomas identifies recurrent mutations in TP53, KMT genes and PDGFB fusions
Autor: Sunetra Das, Rupa Idate, Susan E. Lana, Daniel P. Regan, Dawn L. Duval
Publikováno v: Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract Soft tissue sarcomas (STS) are a heterogenous group of mesenchymal tumors representing over 50 distinct types with overlapping histological features and non-specific anatomical locations. Currently, localized sarcomas are treated with surger
Externí odkaz: https://doaj.org/article/72be33ec9b314d078fe5be7813f778cc
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3
Akademický článek
Immune pathways and TP53 missense mutations are associated with longer survival in canine osteosarcoma
Autor: Sunetra Das, Rupa Idate, Daniel P. Regan, Jared S. Fowles, Susan E. Lana, Douglas H. Thamm, Daniel L. Gustafson, Dawn L. Duval
Publikováno v: Communications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
Sunetra Das et al. combine genetic and immunohistochemistry data to characterize mutation and expression profiles of canine osteosarcoma and its association with clinical outcomes. Their results provide further insight into the pathogenesis and poten
Externí odkaz: https://doaj.org/article/40f18b0edf8e479584b48c155d3b6eee
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4
Supplementary Materials and Methods and Supplementary Tables S3, S4, S6, S8, and S9 from Identifying Candidate Druggable Targets in Canine Cancer Cell Lines Using Whole-Exome Sequencing
Autor: Dawn L. Duval, Daniel L. Gustafson, Kathryn E. Cronise, Rupa Idate, Sunetra Das
Section 1: Supplementary Materials and Methods Section 2: Supplementary Tables Supplementary Table S3. Tools and databases used in this study. Supplementary Table S4. Primers used for validating variants. Supplementary Table S6. Putative driver gene
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68044544f6ce6d9c3d8c2f6baf88df7d
https://doi.org/10.1158/1535-7163.22507174
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5
Supplementary Tables S1, S2, S5, and S7 from Identifying Candidate Druggable Targets in Canine Cancer Cell Lines Using Whole-Exome Sequencing
Autor: Dawn L. Duval, Daniel L. Gustafson, Kathryn E. Cronise, Rupa Idate, Sunetra Das
Supplementary Table S1A. Metadata associated with canine cancer cell line panel. Supplementary Table S1B. Metadata associated with normal samples. Supplementary Table S2. Certificate of Analysis - Cell Line Validation. Supplementary Table S5. List of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e498599bcb45398058fcc3d87dee38a
https://doi.org/10.1158/1535-7163.22507171.v1
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6
Supplementary Figs. S1 - S6 from Identifying Candidate Druggable Targets in Canine Cancer Cell Lines Using Whole-Exome Sequencing
Autor: Dawn L. Duval, Daniel L. Gustafson, Kathryn E. Cronise, Rupa Idate, Sunetra Das
Supplementary Fig. S1. Pipeline for post-processing of somatic variants. Supplementary Fig. S2. Distribution of genes and variants. Supplementary Fig. S3. MDM2 and TP53 transcript levels. Supplementary Fig. S4. KEGG MAPK pathway. Supplementary Fig. S
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0da1f3d979e23a02b85b3abbd3888e97
https://doi.org/10.1158/1535-7163.22507177
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7
Data from Identifying Candidate Druggable Targets in Canine Cancer Cell Lines Using Whole-Exome Sequencing
Autor: Dawn L. Duval, Daniel L. Gustafson, Kathryn E. Cronise, Rupa Idate, Sunetra Das
Cancer cell culture has been a backbone in cancer research, in which analysis of human cell line mutational profiles often correlates with oncogene addiction and drug sensitivity. We have conducted whole-exome sequence analyses on 33 canine cancer ce
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a1a79c1f91877731d63c1cc47f222e88
https://doi.org/10.1158/1535-7163.c.6538609.v1
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10
Immune pathways and TP53 missense mutations are associated with longer survival in canine osteosarcoma
Autor: Dawn L. Duval, Rupa Idate, Douglas H. Thamm, Daniel L. Gustafson, Jared S. Fowles, Daniel P. Regan, Sunetra Das, Susan E. Lana
Publikováno v: Communications Biology
Communications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
Osteosarcoma affects about 2.8% of dogs with cancer, with a one-year survival rate of approximately 45%. The purpose of this study was to characterize mutation and expression profiles of osteosarcoma and its association with outcome in dogs. The numb
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::803052d3f343fab983f9f9efc587a465
http://europepmc.org/articles/PMC8505454
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