Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Rupa Devi Soligalla"'
Autor:
Fumiyuki Hatanaka, Tomoaki Hishida, Pradeep Reddy, Emi Aizawa, Pedro Guillen, Alejandro Ocampo, Josep M. Campistol, Reyna Hernández-Benítez, Pierre J. Magistretti, Masahiro Sakurai, Concepcion Rodriguez Esteban, Ying Gu, Guang-Hui Liu, Masakazu Kurita, Keiichiro Suzuki, Zhe Li, Mako Yamamoto, Juan Carlos Izpisua Belmonte, Yilin Yuan, Amy N. Nemeth, Jun Wu, Estrella Nuñez Delicado, Carlos López-Otín, Christopher Wei, Jianhui Gong, Rupa Devi Soligalla, Kun Zhang
Publikováno v:
Cell research, vol 29, iss 10
Cell Res
Cell Res
In vivo genome editing represents a powerful strategy for both understanding basic biology and treating inherited diseases. However, it remains a challenge to develop universal and efficient in vivo genome-editing tools for tissues that comprise dive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c675f81e450057189474345522e38d04
https://escholarship.org/uc/item/2pn850cq
https://escholarship.org/uc/item/2pn850cq
Autor:
Euiseok J. Kim, Tomoaki Hishida, Fumiyuki Hatanaka, Estrella Núñez-Delicado, Edward M. Callaway, Shicheng Guo, Pierre J. Magistretti, Kang Zhang, Tingshuai Jiang, Reyna Hernández-Benítez, Kun Zhang, Jie Zhu, Concepcion Rodriguez Esteban, Masakazu Kurita, W. Travis Berggren, Jun Wu, Mo Li, Song Chen, Pedro Guillen, Yuji Tsunekawa, April Goebl, Toshikazu Araoka, Jing Qu, Rupa Devi Soligalla, Jeronimo Lajara, Maryam Jafari, Guang-Hui Liu, Keiichiro Suzuki, Fumio Matsuzaki, Mako Yamamoto, Zhe Li, Xin Fu, Juan Carlos Izpisua Belmonte, Emi Aizawa, Josep M. Campistol
Publikováno v:
Nature. 540:144-149
Targeted genome editing via engineered nucleases is an exciting area of biomedical research and holds potential for clinical applications. Despite rapid advances in the field, in vivo targeted transgene integration is still infeasible because current
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d39f934777741fe64b1b1bd4ebd49700
https://doi.org/10.1038/nature20565
https://doi.org/10.1038/nature20565
Autor:
Fuchou Tang, Junzhi Zhou, Weiqi Zhang, Zhichao Ding, Fuquan Yang, Huize Pan, Rupa Devi Soligalla, Shunlei Duan, Dee Guan, Guang-Hui Liu, Jiping Yang, Juan Carlos Izpisua Belmonte, Emi Aizawa, Ying Li, Jingyi Li, Xiaomeng Liu, Fei Yi, Ruotong Ren, Pradeep Reddy, Mo Li, Xiuling Xu, Keiichiro Suzuki, Alejandro Ocampo, Ping Wang, Ruijun Bai, Concepcion Rodriguez Esteban, Jing Qu, Tingting Yuan, Zimei Wang, Yayu Wang, April Goebl, Liang Shi, Xiaoyu Li, Chang Chen
Publikováno v:
Science. 348:1160-1163
Heterochromatin in aging stem cells Analysis of human aging syndromes, such as Werner syndrome (WS), may lead to greater understanding of both premature and normal aging. Zhang et al. generated isogenic WS-specific human embryonic stem cell lines (se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::364bc59c6c8408b934e2535e364371cf
https://doi.org/10.1126/science.aaa1356
https://doi.org/10.1126/science.aaa1356
Autor:
Weiqi, Zhang, Jingyi, Li, Keiichiro, Suzuki, Jing, Qu, Ping, Wang, Junzhi, Zhou, Xiaomeng, Liu, Ruotong, Ren, Xiuling, Xu, Alejandro, Ocampo, Tingting, Yuan, Jiping, Yang, Ying, Li, Liang, Shi, Dee, Guan, Huize, Pan, Shunlei, Duan, Zhichao, Ding, Mo, Li, Fei, Yi, Ruijun, Bai, Yayu, Wang, Chang, Chen, Fuquan, Yang, Xiaoyu, Li, Zimei, Wang, Emi, Aizawa, April, Goebl, Rupa Devi, Soligalla, Pradeep, Reddy, Concepcion Rodriguez, Esteban, Fuchou, Tang, Guang-Hui, Liu, Juan Carlos Izpisua, Belmonte
Publikováno v:
Science (New York, N.Y.). 348(6239)
Werner syndrome (WS) is a premature aging disorder caused by WRN protein deficiency. Here, we report on the generation of a human WS model in human embryonic stem cells (ESCs). Differentiation of WRN-null ESCs to mesenchymal stem cells (MSCs) recapit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::029d03a2ee13c4bac51a6a7ce2668a56
https://pubmed.ncbi.nlm.nih.gov/26045423
https://pubmed.ncbi.nlm.nih.gov/26045423
Autor:
Weiqi Zhang, April Goebl, Jordi Surrallés, Concepcion Rodriguez Esteban, Nuria Montserrat, Juan A. Bueren, Sergio Ruiz, Xiuling Xu, Antonio del Sol, Carlo Dufour, Emmanuel Nivet, Yuji Tsunekawa, Keiichiro Suzuki, Ruotong Ren, Na Young Kim, Juan Carlos Izpisua Belmonte, Mo Li, Kun Zhang, Ying Gu, Enrico Cappelli, Jing Qu, Ilir Dubova, Jessica Kim, Ying Li, Fei Yi, Emi Aizawa, Juan P. Trujillo, Guang-Hui Liu, Rupa Devi Soligalla, Carolina Tarantino, Christopher Benner, Shigeo Masuda, Nongluk Plongthongkum
Publikováno v:
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Universitat Autònoma de Barcelona
Fanconi anaemia (FA) is a recessive disorder characterized by genomic instability, congenital abnormalities, cancer predisposition and bone marrow (BM) failure. However, the pathogenesis of FA is not fully understood partly due to the limitations of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::daf144ceb57d2908e7275dbb9df8acf1
https://doi.org/10.1038/ncomms5330
https://doi.org/10.1038/ncomms5330
Autor:
Guang-Hui Liu, Yingrui Li, Chang Yu, Keiichiro Suzuki, Xiuling Xu, Xiaotian Yao, Senwei Tang, Yabin Jin, Hsin-Kai Liao, Rupa Devi Soligalla, Jessica Kim, Jing Qu, Tingting Yuan, Ruotong Ren, Fan Zhang, Emi Aizawa, Juan Carlos Izpisua Belmonte, Mo Li, April Goebl, Feng Chen, Concepcion Rodriguez Esteban, Christopher Benner, Na Young Kim
Publikováno v:
Cell stem cell. 15(1)
SummaryThe utility of genome editing technologies for disease modeling and developing cellular therapies has been extensively documented, but the impact of these technologies on mutational load at the whole-genome level remains unclear. We performed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91033efe999b9e660184951c963466ed
https://pubmed.ncbi.nlm.nih.gov/24996168
https://pubmed.ncbi.nlm.nih.gov/24996168
Autor:
Nuria Montserrat, Ilir Dubova, Sergio Ruiz, Jessica Kim, Weiqi Zhang, Ying Li, Fei Yi, Jing Qu, April Goebl, Emmanuel Nivet, Rupa Devi Soligalla, Ulrich Wagner, Juan Carlos Izpisua Belmonte, John R. Yates, Concepcion Rodriguez Esteban, Xiuling Xu, Audrey Kim, Keiichiro Suzuki, James Thompson, Ignacio Sancho-Martinez, Bing Ren, Guang-Hui Liu, Mo Li
Publikováno v:
Nature
Nature, 2012, 491 (7425), pp.603--607. ⟨10.1038/nature11557⟩
Nature, Nature Publishing Group, 2012, 491 (7425), pp.603--607. ⟨10.1038/nature11557⟩
Nature, 2012, 491 (7425), pp.603--607. ⟨10.1038/nature11557⟩
Nature, Nature Publishing Group, 2012, 491 (7425), pp.603--607. ⟨10.1038/nature11557⟩
International audience; Nuclear-architecture defects have been shown to correlate with the manifestation of a number of human diseases as well as ageing. It is therefore plausible that diseases whose manifestations correlate with ageing might be conn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64924e37407b1015c9f1ae18a43620eb
https://hal.science/hal-01736204
https://hal.science/hal-01736204
Autor:
Ignacio Sancho-Martinez, Nongluk Plongthongkum, Jing Qu, Ho-Lim Fung, Rupa Devi Soligalla, Louise C. Laurent, Fei Yi, Guang-Hui Liu, Kun Zhang, Emmanuel Nivet, Juan Carlos Izpisua Belmonte, Keiichiro Suzuki, Mo Li, April Goebl, Jeanne F. Loring, Sachin Kumar, Jessica Kim, Ilir Dubova
Publikováno v:
Cell Stem Cell
Cell Stem Cell, 2011, 8 (6), pp.688--694. ⟨10.1016/j.stem.2011.04.019⟩
Cell Stem Cell, 2011, 8 (6), pp.688--694. ⟨10.1016/j.stem.2011.04.019⟩
International audience; Combination of stem cell-based approaches with gene-editing technologies represents an attractive strategy for studying human disease and developing therapies. However, gene-editing methodologies described to date for human ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a931355aed1a542df362d090bd0a293