Výsledky vyhledávání

Toll-Like Receptor Signalling Pathways Regulate Hypoxic Stress Induced Fibroblast Growth Factor but Not Vascular Endothelial Growth Factor-A in Human Microvascular Endothelial Cells

Autor: Winfried M Amoaku, Rukhsar Akhtar, Imran Mohammed, Elizabeth Stewart, Husain Tahir, Ruoxin Wei

Publikováno v: International Journal of Translational Medicine
Volume 1
Issue 1
Pages 3-38

Retinal diseases are the leading causes of irreversible blindness worldwide. The role of toll-like receptor (TLR) signalling mechanisms (MyD88 and TRIF) in the production of pro-angiogenic growth factors from human microvascular endothelial cells (HM

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e97d8e48013c5f42ec1eaaa78f904c7a

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Outcome and risk of ocular complications of managing children with chronic anterior uveitis with topical rimexolone 1

Autor: Xiaozhe Zhang, Yi-Hsing Chen, Oren Tomkins-Netzer, Ruoxin Wei, Susan Lightman, Hsiao-Jung Tseng, Lazha Sharief, Raz Gepstein

Publikováno v: International ophthalmology. 40(5)

To investigate the efficacy and safety of 1% rimexolone ophthalmic suspension in children with chronic anterior uveitis under real-life conditions in a tertiary center.This is a retrospective longitudinal study. Medical records were analyzed at basel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f24c0e130b0930d1c690c7665086d836
https://pubmed.ncbi.nlm.nih.gov/32318939

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Expression of Toll-like receptors in human retinal and choroidal vascular endothelial cells

Autor: Matthew J. Branch, Laura E. Sidney, Winfried M Amoaku, Elizabeth A. Stewart, Ruoxin Wei

Publikováno v: Experimental Eye Research. 138:114-123

Toll-like receptors (TLRs) are a family of proteins that initiate the innate immune response in reaction to invading microbes. Studies confirm the expression of TLRs in a variety of ocular tissues and cells, and it has also been suggested that select

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1d85ad6cbc6b11581041d8960472617
https://doi.org/10.1016/j.exer.2015.06.012

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Functional Expression of Toll-Like Receptors in Human Retinal and Choroidal Vascular Endothelial Cells

Autor: W. Amoaku, Ruoxin Wei, Matthew J. Branch, Laura E. Sidney, Elizabeth A. Stewart

Publikováno v: Acta Ophthalmologica. 93

Purpose Toll-like receptors (TLRs) are a family of proteins that initiate the innate immune response in reaction to invading microbes. Studies confirm the expression of TLRs in a variety of ocular tissues and cells, and it has also been suggested tha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04eb02b00085ed0c8dc89dfd0103d1ed
https://doi.org/10.1111/j.1755-3768.2015.1630

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Stimulation of TLR4 Increases Angiogenic and Anti-Angiogenic Gene Expression in Choroidal Endothelial Cells

Autor: W. Amoaku, Ruoxin Wei, M. Uribe, S. May, E. Stewart

Publikováno v: Acta Ophthalmologica. 93

Purpose The Toll-like receptor (TLR) family initiate the innate immune response in reaction to invading microbes. Studies confirm the expression of TLRs in a variety of ocular tissues and cells, and it has also been suggested that selected TLRs may b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dc134450a088e21b41ea315f42f21140
https://doi.org/10.1111/j.1755-3768.2015.0627

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Efficacy of tetrandrine on lowering intraocular pressure in animal model with ocular hypertension

Autor: Samuel Shao Min Zhang, Jing Liu, Chun Zhang, Yongsheng Xu, Haiping Li, Yong Tang, Ruoxin Wei, Ping Huang

Publikováno v: Journal of glaucoma. 20(3)

Purpose To compare the efficacy of topical tetrandrine (an alkaloid isolated from the Chinese medicinal herb Radix Stephania tetrandrae S) and timolol 0.5% ophthalmic solution on lowering the intraocular pressure (IOP) in ocular normotensive and hype

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f167afc52f9518c087788f3ffa2bf0fc
https://pubmed.ncbi.nlm.nih.gov/20440217

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A glycine site-specific NMDA receptor antagonist protects retina ganglion cells from ischemic injury by modulating apoptotic cascades

Autor: Wei Wang, Chi Zhang, Weiqiang Qiu, Wen Leng, Chun Zhang, Ruoxin Wei

Publikováno v: Journal of cellular physiology. 223(3)

Glutamate neurotoxicity is one of the causative factors leading to neural degeneration including retina. Inhibition of NMDA receptors has been shown neuroprotective effects. However, specifically inhibition of glycine subunit in NMDA receptors and it

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e83c245d9a716a46e3ede9c630e184b
https://pubmed.ncbi.nlm.nih.gov/20333677

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Akademický článek

Expression of Toll-like receptors in human retinal and choroidal vascular endothelial cells.

Autor: Stewart, Elizabeth A., Ruoxin Wei, Branch, Matthew J., Sidney, Laura E., Amoaku, Winfried M. Winfried.amoaku@nottingham.ac.uk

Publikováno v: Experimental Eye Research. Sep2015, Vol. 138, p114-123. 10p.

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Akademický článek

A glycine site-specific NMDA receptor antagonist protects retina ganglion cells from ischemic injury by modulating apoptotic cascades.

Autor: WEIQIANG QIU, RUOXIN WEI, CHI ZHANG, CHUN ZHANG, WEN LENG, WEI WANG

Publikováno v: Journal of Cellular Physiology; Jun2010, Vol. 223 Issue 3, p819-826, 8p, 4 Color Photographs, 2 Charts, 1 Graph

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