Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Ruoxi Lan"'
Autor:
Satenig Guler, Maria C. DiPoto, Alejandro Crespo, Richard Caldwell, Benjamin Doerfel, Nina Grossmann, Kevin Ho, Bayard Huck, Christopher CV Jones, Ruoxi Lan, Djordje Musil, Justin Potnick, Heike Schilke, Brian Sherer, Stephanie Simon, Christian Sirrenberg, Zhuo Zhang, Lesley Liu-Bujalski
Publikováno v:
ACS Medicinal Chemistry Letters. 14:566-576
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::25b39835444913dded430eb8a3077662
https://doi.org/10.1021/acsmedchemlett.2c00481
https://doi.org/10.1021/acsmedchemlett.2c00481
Autor:
Junjuan Wang, Ruolin Song, Ruoxi Lan, Mengzhen Hao, Guirong Liu, Manman Liu, Shanfeng Sun, Cheng Chen, Huilian Che
Publikováno v:
Food & Function. 13:8818-8828
There is no universally accepted uniform research to classify the severity of allergic reactions triggered by different food allergens. We established a food allergy model based on repeated intragastric administrations of proteins from peanut, egg, m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e294fcf0a9cd3086521e6d68cb8dd1a1
https://doi.org/10.1039/d2fo00777k
https://doi.org/10.1039/d2fo00777k
Autor:
Brian H. Heasley, Jing Lin, Thomas F. N. Haxell, Igor Mochalkin, Constantin Neagu, Felix Rohdich, Ruoxi Lan, Amanda E. Sutton, Jennifer Jackson, Potnick Justin, Bayard R. Huck, Andreas Machl, Katrin Georgi, Xiaoling Chen, Sherer Brian A, Erik Wilker, Thomas E. Richardson, Anderson Clark, Reinaldo Jones, Johnson Theresa L, Lizbeth Celeste Deselm, Andreas Goutopoulos, Hui Tian, Yufang Xiao, Joseph A. Moore, Lindsey Crowley
Publikováno v:
Journal of Medicinal Chemistry. 64:14603-14619
Herein, we report the discovery of a novel class of quinazoline carboxamides as dual p70S6k/Akt inhibitors for the treatment of tumors driven by alterations to the PI3K/Akt/mTOR (PAM) pathway. Through the screening of in-house proprietary kinase libr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f0f668e1b7d0d3fdf120a40211a6894
https://doi.org/10.1021/acs.jmedchem.1c01087
https://doi.org/10.1021/acs.jmedchem.1c01087
Autor:
Ruoxi Lan, Hui Tian, Dusica Santos, Lizbeth Celeste Deselm, Jing Lin, Donald Bankston, Constantin Neagu, Sherer Brian A, Jennifer Jackson, Jared Head, Jianguo Ma, Xuliang Jiang, Sakeena Syed, Anderson Clark, Andreas Machl, Yufang Xiao, Erik Wilker, Anna Gardberg, Xiaoling Chen, Igor Mochalkin, Bayard R. Huck, Hui Qiu, Christopher Charles Victor Jones, Vikram Dutt, Johnson Theresa L, Andreas Goutopoulos
Publikováno v:
Bioorganicmedicinal chemistry letters. 50
Activation of the PI3K/Akt/mTOR kinase pathway is associated with human cancers. A dual p70S6K/Akt inhibitor is sufficient to inhibit strong tumor growth and to block negative impact of the compensatory Akt feedback loop activation. A scaffold dockin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c34ccf70712c4f9a6c835cbbed5b0bb
https://pubmed.ncbi.nlm.nih.gov/35484006
https://pubmed.ncbi.nlm.nih.gov/35484006
Publikováno v:
Interactive Learning Environments. 28:148-165
In this study, a situation-based interactive e-book system was developed for improving children’s learning performance of numerical operations. To evaluate the effectiveness of the system, an exper...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4cd949aebef400e3359a943df4151a41
https://doi.org/10.1080/10494820.2019.1636085
https://doi.org/10.1080/10494820.2019.1636085
Autor:
Yufang Xiao, Bayard R. Huck, Ruoxi Lan, Lizbeth DeSelm, Xiaoling Chen, Hui Qiu, Constantin Neagu, Theresa Johnson, Igor Mochalkin, Anna Gardberg, Xuliang Jiang, Hui Tian, Vikram Dutt, Dusica Santos, Jared Head, Jennifer Jackson, Sakeena Syed, Jing Lin, Erik Wilker, Jianguo Ma, Anderson Clark, Andreas Machl, Donald Bankston, Christopher C.V. Jones, Andreas Goutopoulos, Brian Sherer
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 67:128758
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e61734db4df8304c34df6aa92d38de6
https://doi.org/10.1016/j.bmcl.2022.128758
https://doi.org/10.1016/j.bmcl.2022.128758
Autor:
DeSelm, Lizbeth, Huck, Bayard, Ruoxi Lan, Neagu, Constantin, Potnick, Justin, Yufang Xiao, Xiaoling Chen, Jones, Reinaldo, Richardson, Thomas E., Heasley, Brian H., Haxell, Thomas, Moore, Joseph, Hui Tian, Georgi, Katrin, Rohdich, Felix, Sutton, Amanda, Johnson, Theresa, Mochalkin, Igor, Jackson, Jennifer, Jing Lin
Publikováno v:
Journal of Medicinal Chemistry; 10/14/2021, Vol. 64 Issue 19, p14603-14619, 17p
Autor:
Nadia Fortin, Carl Saint-Louis, Annick Landry, René Gagnon, Gilles Olsen, Sylvain Bernard, Patrick Bherer, Eric Marsault, Véronique Plourde, Gilles Berthiaume, Martin Brassard, Robert Deziel, Axel Mathieu, Gérald Villeneuve, Xiaowen Peng, Hamid R. Hoveyda, Mark Peterson, Graeme L. Fraser, François Bilodeau, Ruoxi Lan, Shridhar Bhat, Annie Doucet, Maude Gauthier, Yves L. Dory, David Lonergan, Shigui Li, Sylvie Beaubien, Luc Ouellet, Pierre Deslongchamps, Alexandre Drouin, Fabrice Galaud, Sophie Beauchemin, Manon Champagne, Kamel Benakli, Mahesh Ramaseshan, Laurence Foucher, Jean François Pinault, Martin Vezina, Daniel Fortin, Zhigang Wang
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 18:4731-4735
A new method for solid phase parallel synthesis of chemically and conformationally diverse macrocyclic peptidomimetics is reported. A key feature of the method is access to broad chemical and conformational diversity. Synthesis and mechanistic studie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf941f5cc5a05130451a2464ff661573
https://doi.org/10.1016/j.bmcl.2008.06.085
https://doi.org/10.1016/j.bmcl.2008.06.085
Autor:
Ruoxi Lan, J. Jill Pigg, Gerald H. Wilken, Alexandros Makriyannis, Qian Liu, Devin B. Houston, Allyn C. Howlett
Publikováno v:
Journal of Neurochemistry. 74:2174-2181
3-Azidophenyl- and 3-isothiocyanatophenyl-and 2-(5'-azidopentyl)- and 2-(5'-isothiocyanatopentyl)pyrazoles were synthesized to determine whether these compounds could behave as covalently binding ligands for the CB1 cannabinoid receptor in rat brain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f0e60f7c942b69a8cd356fad6705080
https://doi.org/10.1046/j.1471-4159.2000.0742174.x
https://doi.org/10.1046/j.1471-4159.2000.0742174.x
Publikováno v:
Rapid Communications in Mass Spectrometry. 13:1506-1510
The mass spectrometric behaviour of eight 1a,3-disubstituted 1, 1-dichloro-1,1a,2,3-tetrahydroazirino[2,1-d][1,5]benzothiazepines has been studied with the aid of mass-analyzed ion kinetic energy spectrometry and exact mass measurements under electro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a11cc3d05900be6632227d92ceed630
https://doi.org/10.1002/(sici)1097-0231(19990730)13:14<1506::aid-rcm676>3.0.co
https://doi.org/10.1002/(sici)1097-0231(19990730)13:14<1506::aid-rcm676>3.0.co