Zobrazeno 1 - 10
of 108
pro vyhledávání: '"Ruowen, Wang"'
Publikováno v:
In Science of the Total Environment 1 June 2024 927
Autor:
Ding Ding, Haitao Zhao, Dali Wei, Qinglai Yang, Cai Yang, Ruowen Wang, Yumei Chen, Lianghua Li, Shuxian An, Qian Xia, Gang Huang, Jianjun Liu, Zeyu Xiao, Weihong Tan
Publikováno v:
Research, Vol 6 (2023)
Serving as targeting ligands, aptamers have shown promise in precision medicine. However, the lack of knowledge of the biosafety and metabolism patterns in the human body largely impeded aptamers’ clinical translation. To bridge this gap, here we r
Externí odkaz:
https://doaj.org/article/9bd3bbece46d487bbd0eefd35644efa8
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2023)
Externí odkaz:
https://doaj.org/article/bc8db5fd94b94ba1a9d688dff8b74990
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
Traditional Chinese Medicine (TCM) provides unique therapeutic effects for many diseases with identified efficacy during long practice. Astragalus Membranaceus (AM) is the Chinese herbal applied for kidney injury in the clinic, but it remains challen
Externí odkaz:
https://doaj.org/article/b9ece2282da141e7983a9e66414e8e18
Publikováno v:
Pharmaceutics, Vol 14, Iss 12, p 2781 (2022)
Aptamer–drug conjugates (ApDCs) are potential targeted pharmaceutics, but their clinical applications are hampered by fast clearance in blood. Herein we report the construction of ApDCs modified with artificial base F and the study of biological ac
Externí odkaz:
https://doaj.org/article/89da9e6a8dd94751b095cb817fa7134f
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-7 (2019)
Membrane-anchored DNA probes have been used to study molecular interactions and control cell assembly, but are not selective for different cell membranes. Here the authors develop a lipid-conjugated oligonucleotide for alkaline phosphatase-dependent
Externí odkaz:
https://doaj.org/article/471b75f32e0f4ee2b944649ab12a7268
Site-Specific Radioiodination of Oligonucleotides with a Phenolic Element in a Programmable Approach
Autor:
Haitao Zhao, Yu Qin, Dunfang Liu, Xinyao Geng, Cheng Wang, Ding Ding, Xuan Ding, Qian Xia, Jianjun Liu, Ruowen Wang, Weihong Tan
Publikováno v:
Molecules, Vol 27, Iss 19, p 6257 (2022)
Radioiodination of oligonucleotides provides an extra modality for nucleic acid-based theranostics with potential applications. Herein, we report the design and synthesis of a phosphoramidite embedded with a phenolic moiety and demonstrate that oligo
Externí odkaz:
https://doaj.org/article/51b76e65a1f14a92a4b5b505a999afbe
DNA-modularized construction of bivalent ligands precisely regulates receptor binding and activation
Autor:
Na Zhao, Wenwei Wu, Ying Wang, Kun Song, Gaoxian Chen, Yingzhi Chen, Ruowen Wang, Jianrong Xu, Kai Cui, Hongzhuan Chen, Weihong Tan, Jian Zhang, Zeyu Xiao
Publikováno v:
Chem. 9:1047-1054
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30964d7544c5d2c9bb275ffb6069b6f6
https://doi.org/10.1016/j.chempr.2023.02.005
https://doi.org/10.1016/j.chempr.2023.02.005
Autor:
Yang Sun, Die Yu, Xinyao Geng, Ding Ding, Yu Yang, Zhuang Liu, Zeyu Xiao, Ruowen Wang, Weihong Tan
Publikováno v:
ACS Applied Materials & Interfaces. 15:8872-8883
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e192f03b8cd77710f3c2a152c7984829
https://doi.org/10.1021/acsami.2c19075
https://doi.org/10.1021/acsami.2c19075
Autor:
Ruowen Wang, Xueqiang Wang, Sitao Xie, Yanyan Zhang, Dingkun Ji, Xiaobing Zhang, Cheng Cui, Jianhui Jiang, Weihong Tan
Publikováno v:
Philosophical Transactions of the Royal Society B: Biological Sciences. 378
Classically, a molecular element (ME) is a pure substance composed of two or more atoms of the same element. However, MEs, in the context of this review, can be any molecules as elements bonded together into the backbone of synthetic oligonucleotides
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e66f06e16d1d9e02220a368a2fc6fba
https://doi.org/10.1098/rstb.2022.0024
https://doi.org/10.1098/rstb.2022.0024