Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Ruotian Zhang"'
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Learning effective molecular feature representation to facilitate molecular property prediction is of great significance for drug discovery. Recently, there has been a surge of interest in pre-training graph neural networks (GNNs) via self-s
Externí odkaz:
https://doaj.org/article/3accf436897c4a61889717c8ff87427b
Autor:
Hao Tian, Juanfeng Ou, Yong Wang, Jia Sun, Junbin Gao, Yicheng Ye, Ruotian Zhang, Bin Chen, Fei Wang, Weichang Huang, Huaan Li, Lu Liu, Chuxiao Shao, Zhili Xu, Fei Peng, Yingfeng Tu
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 13, Iss 9, Pp 3862-3875 (2023)
Enzyme-driven micro/nanomotors consuming in situ chemical fuels have attracted lots of attention for biomedical applications. However, motor systems composed by organism-derived organics that maximize the therapeutic efficacy of enzymatic products re
Externí odkaz:
https://doaj.org/article/992fb807fef647b3aeb031a93f93aeff
Autor:
Yanzhen Song, Ruotian Zhang, Hanfeng Qin, Wenxin Xu, Jia Sun, Jiamiao Jiang, Yicheng Ye, Junbin Gao, Huaan Li, Weichang Huang, Kun Liu, Yunrui Hu, Fei Peng, Yingfeng Tu
Publikováno v:
Advanced Science, Vol 10, Iss 33, Pp n/a-n/a (2023)
Abstract Sepsis is a highly heterogeneous syndrome normally characterized by bacterial infection and dysregulated systemic inflammatory response that leads to multiple organ failure and death. Single anti‐inflammation or anti‐infection treatment
Externí odkaz:
https://doaj.org/article/39dd96dbf5ef4d57a8dccb3842fc154e
Autor:
Weichang Huang, Lihong Wen, Hao Tian, Jiamiao Jiang, Meihuan Liu, Yicheng Ye, Junbin Gao, Ruotian Zhang, Fei Wang, Huaan Li, Lihan Shen, Fei Peng, Yingfeng Tu
Publikováno v:
Advanced Science, Vol 10, Iss 27, Pp n/a-n/a (2023)
Abstract Acute lung injury (ALI) is a frequent and serious complication of sepsis with limited therapeutic options. Gaining insights into the inflammatory dysregulation that causes sepsis‐associated ALI can help develop new therapeutic strategies.
Externí odkaz:
https://doaj.org/article/b463d007c5044ad493bddb36f5f7e7a5
Autor:
Yicheng Ye, Hao Tian, Jiamiao Jiang, Weichang Huang, Ruotian Zhang, Huaan Li, Lu Liu, Junbin Gao, Haixin Tan, Meihuan Liu, Fei Peng, Yingfeng Tu
Publikováno v:
Advanced Science, Vol 10, Iss 25, Pp n/a-n/a (2023)
Abstract An efficient and cost‐effective therapeutic vaccine is highly desirable for the prevention and treatment of cancer, which helps to strengthen the immune system and activate the T cell immune response. However, initiating such an adaptive i
Externí odkaz:
https://doaj.org/article/6337f16c48f249468893b18b187aa726
Publikováno v:
Heliyon, Vol 8, Iss 9, Pp e10480- (2022)
Introduction: Long-term treatment with antiepileptic drugs may cause secondary osteoporosis. The present study investigated the influence of simvastatin (SIM) in reversing the effects of valproate on bone defect healing in normal and ovariectomized (
Externí odkaz:
https://doaj.org/article/f24d639c1b6e4756827b010a6b72e54e
Autor:
Tao Yan, Xin Chen, Hua Zhan, Penglei Yao, Ning Wang, He Yang, Cheng Zhang, Kaikai Wang, Hong Hu, Jiafeng Li, Jingxian Sun, Yu Dong, Enzhou Lu, Zhixing Zheng, Ruotian Zhang, Xiaoxiong Wang, Jichao Ma, Ming Gao, Junyi Ye, Xinzhuang Wang, Lei Teng, Huailei Liu, Shiguang Zhao
Publikováno v:
Cell Death and Disease, Vol 12, Iss 5, Pp 1-15 (2021)
Abstract The tumor microenvironment plays an important role in tumor progression. Hyaluronic acid (HA), an important component of the extracellular matrix in the tumor microenvironment, abnormally accumulates in a variety of tumors. However, the role
Externí odkaz:
https://doaj.org/article/0580ac4030984df09f27d3b507d5765e
Autor:
Jiawei Yao, Xin Chen, Zhendong Liu, Ruotian Zhang, Cheng Zhang, Quan Yang, Penglei Yao, Qiuyi Jiang, Jianing Wu, Shiguang Zhao
Publikováno v:
Chinese Neurosurgical Journal, Vol 7, Iss 1, Pp 1-9 (2021)
Abstract Background Glioma is the most common malignant brain tumor in adults. The standard treatment scheme of glioma is surgical resection combined alternative radio- and chemotherapy. However, the outcome of glioma patients was unsatisfied. Here,
Externí odkaz:
https://doaj.org/article/217d6679e84b4b12b5839fe5d39d38a6
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 16, Iss 1, Pp 1-10 (2021)
Abstract Background The use of antiepileptic drugs and estrogen deficiency put forward higher requirements for bone defect regeneration. The present study investigated the effects of alendronate (ALN) on femoral bone defect in ovariectomized (OVX) ra
Externí odkaz:
https://doaj.org/article/941510ce613e4d8599fd394d28f21b12
Autor:
Guang Yang, Lu Wang, Jingxian Sun, Daming Zhang, Ruotian Zhang, Chao Yuan, Meixin Long, Yingqiang Zhong, Chunmei Li, Xiaoxiong Wang, Xin Chen, Qi Zhou, Bo Liu, Hongquan Jiang, Ailing Lian, Ilgiz Gareev, Lili Li, Shiguang Zhao
Publikováno v:
Brain and Behavior, Vol 10, Iss 7, Pp n/a-n/a (2020)
Abstract Introduction Few studies of the effect of cardiac abnormalities on acute intracerebral hemorrhage (ICH) outcomes have been published. We sought to determine whether the left ventricular ejection fraction (LVEF) is associated with the functio
Externí odkaz:
https://doaj.org/article/59036547fcae427590e895f5801532af