Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Ruoshi Yuan"'
Publikováno v:
Royal Society Open Science, Vol 8, Iss 11 (2021)
Haematopoietic lineage commitments are presented by a canonical roadmap in which haematopoietic stem cells or multipotent progenitors (MPPs) bifurcate into progenitors of more restricted lineages and ultimately mature to terminally differentiated cel
Externí odkaz:
https://doaj.org/article/4deba5b539624b108723a09525244617
Publikováno v:
Frontiers in Physics, Vol 9 (2021)
Divergence is usually used to determine the dissipation of a dynamical system, but some researchers have noticed that it can lead to elusive contradictions. In this article, a criterion, dissipative power, beyond divergence for judging the dissipatio
Externí odkaz:
https://doaj.org/article/6eb313a8e4164811be877a75ba625bae
Autor:
Meimei Zhao, Rui Geng, Xiang Guo, Ruoshi Yuan, Xiao Zhou, Yanyan Zhong, Yanfei Huo, Mei Zhou, Qinjian Shen, Yinglu Li, Weiguo Zhu, Jiadong Wang
Publikováno v:
Cell Reports, Vol 20, Iss 9, Pp 1997-2009 (2017)
The RPA complex can integrate multiple stress signals into diverse responses by activating distinct DNA repair pathways. However, it remains unclear how RPA1 elects to activate a specific repair pathway during different types of DNA damage. Here, we
Externí odkaz:
https://doaj.org/article/33d2ae3800c64303b48af4ced8c35bf3
Autor:
Ruoshi Yuan, Suzhan Zhang, Jiekai Yu, Yanqin Huang, Demin Lu, Runtan Cheng, Sui Huang, Ping Ao, Shu Zheng, Leroy Hood, Xiaomei Zhu
Publikováno v:
Open Biology, Vol 7, Iss 11 (2017)
Colorectal cancer (CRC) has complex pathological features that defy the linear-additive reasoning prevailing in current biomedicine studies. In pursuing a mechanistic understanding behind such complexity, we constructed a core molecular–cellular in
Externí odkaz:
https://doaj.org/article/26f84f3578014f0889b3af9d3ae4a4c4
Self-assembly formation of nanoparticles (NPs) is a central theme in nanotechnology that has garnered significant attention in both academia and industry. The size of self-assembled NPs plays crucial role in their physicochemical properties. It has l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3fc7d17754564698ff4203f524e0f24f
https://doi.org/10.21203/rs.3.rs-2690518/v1
https://doi.org/10.21203/rs.3.rs-2690518/v1
Autor:
Wei Wang, Jiadong Wang, Jun Zhan, Xiao Albert Zhou, Jiadong Zhou, Changfeng Chen, Yan Wang, Long Zhao, Wenjia Zhang, Donghao Xu, Weibin Wang, Zhanlong Shen, Ruoshi Yuan, Chanyi Shi, Yingjiang Ye, Guihui Yu
Publikováno v:
Proc Natl Acad Sci U S A
Aberrant programmed cell death protein 1 (PD-1) expression on the surface of T cells is known to inhibit T cell effector activity and to play a pivotal role in tumor immune escape; thus, maintaining an appropriate level of PD-1 expression is of great
Publikováno v:
Nucleic Acids Research
In synthetic circuits, CRISPR-Cas systems have been used effectively for endpoint changes from an initial state to a final state, such as in logic gates. Here, we use deactivated Cas9 (dCas9) and deactivated Cas12a (dCas12a) to construct dynamic RNA
Publikováno v:
Royal Society Open Science
Royal Society Open Science, Vol 8, Iss 11 (2021)
Royal Society Open Science, Vol 8, Iss 11 (2021)
Haematopoietic lineage commitments are presented by a canonical roadmap in which haematopoietic stem cells or multipotent progenitors (MPPs) bifurcate into progenitors of more restricted lineages and ultimately mature to terminally differentiated cel
Autor:
Xiaojie Qiu, Yan Zhang, Jorge D. Martin-Rufino, Chen Weng, Shayan Hosseinzadeh, Dian Yang, Angela N. Pogson, Marco Y. Hein, Kyung Hoi (Joseph) Min, Li Wang, Emanuelle I. Grody, Matthew J. Shurtleff, Ruoshi Yuan, Song Xu, Yian Ma, Joseph M. Replogle, Eric S. Lander, Spyros Darmanis, Ivet Bahar, Vijay G. Sankaran, Jianhua Xing, Jonathan S. Weissman
Publikováno v:
Cell. 185(4)
Single-cell (sc)RNA-seq, together with RNA velocity and metabolic labeling, reveals cellular states and transitions at unprecedented resolution. Fully exploiting these data, however, requires kinetic models capable of unveiling governing regulatory f
In synthetic circuits, CRISPR-Cas systems have been used effectively for endpoint changes from an initial state to a final state, such as in logic gates. Here, we use deactivated Cas9 (dCas9) and deactivated Cas12a (dCas12a) to construct dynamic RNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82163c90778bad7b949060d044e8241e