Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Ruoqi Xu"'
Autor:
Jing Zhou, Tianjiao Wang, Haoran Zhang, Jianhong Liu, Pengjun Wei, Ruoqi Xu, Qin Yan, Guochun Chen, Wan Li, Shou-Jiang Gao, Chun Lu
Publikováno v:
PLoS Pathogens, Vol 20, Iss 3, p e1012082 (2024)
Ferroptosis, a defensive strategy commonly employed by the host cells to restrict pathogenic infections, has been implicated in the development and therapeutic responses of various types of cancer. However, the role of ferroptosis in oncogenic Kaposi
Externí odkaz:
https://doaj.org/article/3500e0653c5d4281917a5aa8dc5d405b
Autor:
Nicholas A. Arce, Wenpeng Cao, Alexander K. Brown, Emily R. Legan, Moriah S. Wilson, Emma-Ruoqi Xu, Michael C. Berndt, Jonas Emsley, X. Frank Zhang, Renhao Li
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Von Willebrand factor (VWF) is a large glycoprotein in the blood secreted from endothelial cells lining the blood vessel and activation of VWF leads to formation of VWF-platelet complexes or thrombi. Here authors use single-molecule force measurement
Externí odkaz:
https://doaj.org/article/717c9b35a0aa4d4d8a77c1b7e9fbb9c1
Autor:
Spyros D Chatziefthimiou, Philipp Hornburg, Florian Sauer, Simone Mueller, Deniz Ugurlar, Emma-Ruoqi Xu, Matthias Wilmanns
Publikováno v:
PLoS ONE, Vol 14, Iss 12, p e0226693 (2019)
In striated muscles, molecular filaments are largely composed of long protein chains with extensive arrays of identically folded domains, referred to as "beads-on-a-string". It remains a largely unresolved question how these domains have developed a
Externí odkaz:
https://doaj.org/article/d0254c6b8eb74b8085f90d3eb325de21
Autor:
Emily R. Legan, Emma-Ruoqi Xu, Michael C. Berndt, Nicholas A Arce, Jonas Emsley, Alexander K. Brown, Wenpeng Cao, Renhao Li, Moriah Simone Wilson, X. Frank Zhang
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Nature Communications
Nature Communications
Von Willebrand factor (VWF) activates in response to shear flow to initiate hemostasis, while aberrant activation could lead to thrombosis. Above a critical shear force, the A1 domain of VWF becomes activated and captures platelets via the GPIb-IX co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe2353e46afa4e83a3d1f65b2b13b40e
https://doaj.org/article/717c9b35a0aa4d4d8a77c1b7e9fbb9c1
https://doaj.org/article/717c9b35a0aa4d4d8a77c1b7e9fbb9c1
Autor:
Po-chia Chen, Fabian Kutzki, Angelika Mojzisch, Bernd Simon, Emma-Ruoqi Xu, Camilo Aponte-Santamaría, Kai Horny, Cy Jeffries, Reinhard Schneppenheim, Matthias Wilmanns, Maria A. Brehm, Frauke Gräter, Janosch Hennig
Publikováno v:
Journal of Structural Biology. 214:107923
Von Willebrand disease (VWD) is a bleeding disorder with different levels of severity. VWD-associated mutations are located in the von Willebrand factor (VWF) gene, coding for the large multidomain plasma protein VWF with essential roles in hemostasi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f128e7743c3fd91f6d86c499fe4e8876
https://doi.org/10.1016/j.jsb.2022.107923
https://doi.org/10.1016/j.jsb.2022.107923
Autor:
Natalie Hellermann, Alexander Tischer, Cécile V. Denis, Reinhard Schneppenheim, Winfried März, Tobias Obser, Maria A. Brehm, Emma Ruoqi Xu, Volker Huck, Ulrike Klemm, Rainer B. Zotz, Matthew Auton, Matthias Wilmanns, Stefan W. Schneider
Publikováno v:
Blood. 133:356-365
The frequent von Willebrand factor (VWF) variant p.Phe2561Tyr is located within the C4 domain, which also harbors the platelet GPIIb/IIIa-binding RGD sequence. To investigate its potential effect on hemostasis, we genotyped 865 patients with coronary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a38836f705c5eacb33baa5c2f642eb7d
https://doi.org/10.1182/blood-2018-04-843425
https://doi.org/10.1182/blood-2018-04-843425
Autor:
Kenton P. Arkill, Vivin Karthik, Jonas Emsley, Emma-Ruoqi Xu, Mohamed Halawa, Zubair Ahmed Nizamudeen, Andrew Jackson, David O. Bates
Publikováno v:
Bioscience Reports
ORF7a is an accessory protein common to SARS-CoV1 and the recently discovered SARS-CoV2, which is causing the COVID-19 pandemic. The ORF7a protein has a structural homology with ICAM-1 which binds to the T lymphocyte integrin receptor LFA-1. As COVID
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ea0d99f1ca76f1118cc38252cc9b8e7
Autor:
Matthias Wilmanns, Stefan W. Schneider, Maria A. Brehm, Volker Huck, Cécile V. Denis, Po-chia Chen, Gesa König, Frauke Gräter, Emma Ruoqi Xu, Christian Mess, Reinhard Schneppenheim, Fabian Kutzki, Tobias Obser, Ulrike Klemm, Matthew Auton, Alexander Tischer, Janosch Hennig, Camilo Aponte-Santamaría
Publikováno v:
Thrombosis and Haemostasis, 5
Thrombosis and haemostasis 122(02), 226-239 (2022). doi:10.1055/a-1344-4405
Thrombosis and haemostasis 122(02), 226-239 (2022). doi:10.1055/a-1344-4405
Thrombosis and haemostasis 122(02), 226 - 239 (2022). doi:10.1055/a-1344-4405
The multimeric plasma glycoprotein (GP) von Willebrand factor (VWF) is best known for recruiting platelets to sites of injury during primary hemostasis. Generally, mut
The multimeric plasma glycoprotein (GP) von Willebrand factor (VWF) is best known for recruiting platelets to sites of injury during primary hemostasis. Generally, mut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::676e2ffd5d34afa56c122f34b9f9a2b4
https://pubmed.ncbi.nlm.nih.gov/33385180
https://pubmed.ncbi.nlm.nih.gov/33385180
Autor:
Chunhe Zhang, Qiuyu Zhang, Dongliang Yang, Juan Zhang, Fengyan Yang, Guiran Yang, Yuan Zhou, Ruoqi Xu, Yanguo Li, Shuzhen Li, Yaxian Pang, Caihong Hu, Mingqing Liu, Tong Zhang, Ruixia Yan
Background: Patients with thyroid nodules may be complicated by hypothyroidism. However, effective means to predict thyroid-stimulating hormone (TSH) elevation in patients with thyroid nodules are currently lacking. Therefore, the research team recru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc41a8b26f647724babff974df519324
https://doi.org/10.21203/rs.3.rs-134775/v1
https://doi.org/10.21203/rs.3.rs-134775/v1
Autor:
Emma-Ruoqi Xu, Jonas Emsley
Publikováno v:
Blood. 137:2865-2866
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::178f74ef22f49c3bba9c4b7f1aa0fa7e
https://doi.org/10.1182/blood.2021010716
https://doi.org/10.1182/blood.2021010716