Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Ruonan Ning"'
Autor:
Yuxin Zhang, Jiahui Zhang, Zhongyi Sun, Hui Wang, Ruonan Ning, Longyu Xu, Yichen Zhao, Kai Yang, Xiaobing Xi, Jiwei Tian
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundIntervertebral disc degeneration (IDD) is one of the most common health problems in the elderly and a major causative factor in low back pain (LBP). An increasing number of studies have shown that IDD is closely associated with autophagy an
Externí odkaz:
https://doaj.org/article/2c0558f06d534239a12eb51e7bdc5b7f
Autor:
Hao Tian, Tao Jiang, Kai Yang, Ruonan Ning, Tianqi Wang, Qi Zhou, Niandong Qian, Ping Huang, Lei Guo, Min Jiang, Xiaobing Xi, Xing Xu, Lianfu Deng
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Osteoporosis (OP) is defined as low bone mineral density which features over activated osteoclasts (OCs) and bone resorption. Targeting excessive OCs activity is thought to be an effective therapeutic approach for OP treatment. α-asarone (ASA), a co
Externí odkaz:
https://doaj.org/article/66ae35d4938649f7bac26dac0882d097
Autor:
Xiaojing Wang, Hanzhi Zhang, Zhijun Yang, Jing Liu, Lei Shao, Junhai Huang, Kai Wu, Ruonan Ning
Publikováno v:
Journal of Chemical Technology & Biotechnology. 96:3066-3073
Autor:
Kai Yang, Shunyao Li, Tianqi Wang, Xueming Yan, Qian He, Ruonan Ning, Xing Xu, Wei Yao, Xiaofei Zhang, Chunhao Yang, Min Jiang, Lianfu Deng
Publikováno v:
Journal of medicinal chemistry. 65(16)
Receptor activator of nuclear factor-κB (RANK) and its ligand, RANKL, play pivotal roles in bone remodeling. The monoclonal antibody denosumab successfully inhibited the maturation of osteoclasts (OCs) by binding to RANKL in the clinic. We continued
Autor:
Lin Yang, Dongling Jia, Yifan Zhang, Ruonan Ning, Hongzhi Pan, Yuqing Miao, Peiying Feng, Xue Zhang
Publikováno v:
Environmental Science: Nano. 8:415-431
Metallic Bi nanoparticle-decorated g-C3N4 nanosheet (BiNPs/g-C3N4) heterostructures are fabricated by employing a simple ultrasound-assisted electrostatic self-assembly method. It is observed that BiNPs with a diameter of about 7 nanometer are unifor
Publikováno v:
Journal of agricultural and food chemistry. 70(2)
Dihydro-β-agarofuran-type sesquiterpenoids are characteristic metabolites of Celastraceae plants, and the extracts of these plants have been developed into botanical pesticides. In the course of our efforts to find novel natural biologically active
Autor:
Wei Wang, Yingdong Zhu, Wei-Min Zhao, Shuangzhu Liu, Ru-Jun Zhang, Ruonan Ning, Huan Wang, Hai-Yan Zhang, Yun Lei
Publikováno v:
Journal of Natural Products. 78:2175-2186
Alzheimer's disease (AD) is an irreversible, multifaceted, and progressive neurodegenerative disorder. Over the past 30 years, the search for anti-AD drugs has been primarily based on the cholinergic deficiency hypothesis and/or the β-amyloid (Aβ)
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 24:5395-5398
Chemical investigation of the cupules of Lithocarpus polystachyus resulted in the identification of four 3,4-seco-homo-cycloartane and one homo-cycloartane derivatives named lithocarpic acids O-S. Their structures were determined based on extensive 1
Lithocarpic Acids A–N, 3,4-seco-Cycloartane Derivatives from the Cupules of Lithocarpus polystachyus
Autor:
Hong-Min Wang, Ru-Jun Zhang, Ruonan Ning, Yu Shen, Ying Leng, Wei-Min Zhao, Zhen-Hua Chen, Jin-Long Li
Publikováno v:
Journal of Natural Products. 77:1910-1920
Fourteen new 3,4-seco-cycloartane-type triterpenes, lithocarpic acids A-N (1-14), together with one known compound, coccinetane E (15), were identified from the cupules of Lithocarpus polystachyus. The structures of 1-14 were determined by spectrosco
Publikováno v:
Journal of natural products. 79(12)
Seventeen β-dihydroagarofuran-type sesquiterpenes were isolated from the seeds of Celastrus monospermus, and, among them, 15 (1–15) were identified as new natural products. Nine isolates were evaluated for their lifespan-extending effect using the