Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Ruolan Qian"'
Autor:
Siying Wang, Yangyang Zhou, Ruobing Yu, Jing Ling, Botai Li, Chen Yang, Zhuoan Cheng, Ruolan Qian, Zhang Lin, Chengtao Yu, Jiaojiao Zheng, Xingling Zheng, Qi Jia, Wei Wu, Qiangxin Wu, Mengnuo Chen, Shengxian Yuan, Wei Dong, Yaoping Shi, Robin Jansen, Yujun Hao, Ming Yao, Wenxin Qin, Haojie Jin
Publikováno v:
JHEP Reports, Vol 5, Iss 10, Pp 100843- (2023)
Background & Aims: Exploiting key regulators responsible for hepatocarcinogenesis is of great importance for the prevention and treatment of hepatocellular carcinoma (HCC). However, the key players contributing to hepatocarcinogenesis remain poorly u
Externí odkaz:
https://doaj.org/article/2b9a76a9f8dc434a842fc6f8be8e1f2b
Autor:
Chen Yang, Senquan Zhang, Zhuoan Cheng, Zhicheng Liu, Linmeng Zhang, Kai Jiang, Haigang Geng, Ruolan Qian, Jun Wang, Xiaowen Huang, Mo Chen, Zhe Li, Wenxin Qin, Qiang Xia, Xiaonan Kang, Cun Wang, Hualian Hang
Publikováno v:
Genome Medicine, Vol 14, Iss 1, Pp 1-19 (2022)
Abstract Background Numerous studies have used multi-region sampling approaches to characterize intra-tumor heterogeneity (ITH) in hepatocellular carcinoma (HCC). However, conventional multi-region sampling strategies do not preserve the spatial deta
Externí odkaz:
https://doaj.org/article/d20961f1c7004cf0985792dab1e062f1
Autor:
Chen Yang, Hailin Zhang, Mengnuo Chen, Siying Wang, Ruolan Qian, Linmeng Zhang, Xiaowen Huang, Jun Wang, Zhicheng Liu, Wenxin Qin, Cun Wang, Hualian Hang, Hui Wang
Publikováno v:
eLife, Vol 11 (2022)
Pharmacologic perturbation projects, such as Connectivity Map (CMap) and Library of Integrated Network-based Cellular Signatures (LINCS), have produced many perturbed expression data, providing enormous opportunities for computational therapeutic dis
Externí odkaz:
https://doaj.org/article/2bf05f54ac574e679d0be89137dde479
Autor:
Haigang, Geng, Ruolan, Qian, Linmeng, Zhang, Chen, Yang, Xiang, Xia, Cun, Wang, Gang, Zhao, Zizhen, Zhang, Chunchao, Zhu
Publikováno v:
Aging. 14:6358-6376
Gastric cancer (GC) is one of the most aggressive malignant tumors worldwide. Ferroptosis is a kind of iron-dependent cell death, which is proved to be closely related to tumor progression. In this study, we aim at constructing a ferroptosis-related
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7e7532609d5b552e651c4d40f6ff305
https://doi.org/10.18632/aging.204227
https://doi.org/10.18632/aging.204227
Autor:
Linmeng Zhang, Chen Yang, Xiaowen Huang, Yuchen Guo, Wenxin Qin, Ruolan Qian, Xuhui Ma, Zhicheng Liu, Dayong Zhang, Jun Wang, Huimin Chen, Yiwen Huang, Cun Wang
Publikováno v:
Theranostics
Almost all the current therapies against liver cancer are based on the “one size fits all” principle and offer only limited survival benefit. Fortunately, synthetic lethality (SL) may provide an alternate route towards individualized therapy in l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f97e69a2fa1646ec8b0a67e8609d1a4d
http://europepmc.org/articles/PMC8419043
http://europepmc.org/articles/PMC8419043
Autor:
Siying Wang, Mengnuo Chen, Hailin Zhang, Chen Yang, Ruolan Qian, Linmeng Zhang, Xiaowen Huang, Jun Wang, Zhicheng Liu, Wenxin Qin, Cun Wang, Hualian Hang, Hui Wang
Publikováno v:
eLife. 11
Pharmacologic perturbation projects, such as Connectivity Map (CMap) and Library of Integrated Network-based Cellular Signatures (LINCS), have produced many perturbed expression data, providing enormous opportunities for computational therapeutic dis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c78b7f23cb3401082c335c8630ef7375
https://doi.org/10.7554/elife.71880
https://doi.org/10.7554/elife.71880
Autor:
Siying Wang, Mengnuo Chen, Hailin Zhang, Chen Yang, Ruolan Qian, Linmeng Zhang, Xiaowen Huang, Jun Wang, Zhicheng Liu, Wenxin Qin, Cun Wang, Hualian Hang, Hui Wang
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::36dcf4c91c783468b471bbb6486d24a5
https://doi.org/10.7554/elife.71880.sa2
https://doi.org/10.7554/elife.71880.sa2
Autor:
Xiaowen Huang, Hualian Hang, Chen Yang, Ruolan Qian, Wenxin Qin, Jun Wang, Siying Wang, Zhicheng Liu, Cun Wang, Mengnuo Chen, Hui Wang
Pharmacologic perturbation projects, such as Connectivity Map (CMap) and Library of Integrated Network-based Cellular Signatures (LINCS), have produced many perturbed expression data, providing enormous opportunities for computational therapeutic dis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c19e56039ad50c030a6937432df65ce
https://doi.org/10.1101/2021.06.29.450305
https://doi.org/10.1101/2021.06.29.450305
Publikováno v:
International Journal of Cancer
Osimertinib is the only Food and Drug Administration‐approved third‐generation epidermal growth factor receptor (EGFR) tyrosine‐kinase inhibitor (TKI). A meta‐analysis was performed to aggregate the mixed results of published clinical trials
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d68d7f1d6dbd8fce39b946cb1cdcc0fd
http://europepmc.org/articles/PMC6590181
http://europepmc.org/articles/PMC6590181
Autor:
Chen Yang, Xuhui Ma, Yuchen Guo, Zhicheng Liu, Cun Wang, Xiaowen Huang, Wenxin Qin, Ruolan Qian, Yiwen Huang, Huimin Chen, Jun Wang, Dayong Zhang
Publikováno v:
SSRN Electronic Journal.
Background: Current therapies against liver cancer all follow the “one fits all” principle, without the capacity to provide individualized treatment regimens, which may be responsible for the fact that almost all of them fail to bring about satis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b6fbbec8c09de100d431eb528873607
https://doi.org/10.2139/ssrn.3831111
https://doi.org/10.2139/ssrn.3831111