Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Ruolan Dong"'
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Backgrounds: The incidence of melanosis coli (MC) has gradually increased annually, attracting significant attention and efforts into this field. A potential risk for MC is the long-term use of anthraquinone laxatives in patients with constipation. M
Externí odkaz:
https://doaj.org/article/c8847fd9fcfe4e0aa45cde6e9499705a
Autor:
Liman Luo, Jinlan Luo, Yueting Cai, Menglu Fu, Wenhua Li, Lili Shi, Jingrui Liu, Ruolan Dong, Xizhen Xu, Ling Tu, Yan Yang
Publikováno v:
Pharmacological Research, Vol 183, Iss , Pp 106367- (2022)
Diabetic nephropathy (DN) is the most common cause of end-stage renal disease, and few treatment options that prevent the progressive loss of renal function are available. Studies have shown that dietary fiber intake improves kidney diseases and meta
Externí odkaz:
https://doaj.org/article/2b6d5a38820a492d86b2781e44bb60b8
Autor:
Fan Wu, Qingqing Shao, Zhe Cheng, Xinyu Xiong, Ke Fang, Yan Zhao, Ruolan Dong, Lijun Xu, Fuer Lu, Guang Chen
Publikováno v:
Chinese Medicine, Vol 16, Iss 1, Pp 1-17 (2021)
Abstract Background Accumulating evidence indicated that necroptosis plays an essential role in the pathogenesis of inflammatory bowel disease (IBD). The O-linked β-N-acetylglucosaminylation (O-GlcNAcylation) of necroptotic signal molecule receptor-
Externí odkaz:
https://doaj.org/article/c039ceb2237f4a69a402d211b35644c8
Autor:
Zhe Cheng, Xinyu Xiong, Yi Zhou, Fan Wu, Qingqing Shao, Ruolan Dong, Qiong Liu, Lingli Li, Guang Chen
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 146, Iss , Pp 112491- (2022)
Objectives: Accumulating studies revealed that 6-gingerol, a compound extracted mainly from ginger, treats obesity by preventing hyperlipidemia in vivo induced by high-fat-diet (HFD). The present study intends to further evaluate the efficacy of 6-gi
Externí odkaz:
https://doaj.org/article/392bd6254d0641dca11d3deb298207e8
Autor:
Fan Wu, Yan Zhao, Qingqing Shao, Ke Fang, Ruolan Dong, Shujun Jiang, Fuer Lu, Jinlong Luo, Guang Chen
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Objectives: Natural product, osthole, has been proven to have a protective effect on organ fibrosis, including renal fibrosis. All of these studies are mainly focused on the regulation of TGF-β/Smad signaling pathway. However, due to the pleiotropic
Externí odkaz:
https://doaj.org/article/e70d599c206b4e84a7ad19b386696a3a
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 134, Iss , Pp 111129- (2021)
Ulcerative colitis (UC) is an inflammatory bowel disease with complex pathogenesis, which is affected by genetic factors, intestinal immune status and intestinal microbial homeostasis. Intestinal epithelial barrier defect is crucial to the developmen
Externí odkaz:
https://doaj.org/article/f997359a260644658a0f00426540666d
Publikováno v:
Cellular Physiology and Biochemistry, Vol 42, Iss 2, Pp 761-779 (2017)
Background/Aims: Sepsis is a common disease that continues to increase in prevalence worldwide, and diabetes mellitus may make the situation worse. This study was designed to determine the role of Liver Kinase B1 (LKB1)/adenosine monophosphate-activa
Externí odkaz:
https://doaj.org/article/92a79d6866a94bee8635ecbd64051b50
Autor:
Ruolan Dong, Wenshu Chen, Wenjing Feng, Congying Xia, Danli Hu, Yanjun Zhang, Yan Yang, Dao Wen Wang, Xizhen Xu, Ling Tu
Publikováno v:
Cellular Physiology and Biochemistry, Vol 37, Iss 4, Pp 1592-1606 (2015)
Background/Aims: Bradykinin has been shown to exert a variety of protective effects against vascular injury, and to reduce the levels of several factors involved in the coagulation cascade. A key determinant of thrombin generation is tissue factor (T
Externí odkaz:
https://doaj.org/article/5c808c82459248e7be7f7561e95ea32f
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e77034 (2013)
BACKGROUND: Cell senescence is central to a large body of age related pathology, and accordingly, cardiomyocytes senescence is involved in many age related cardiovascular diseases. In consideration of that, delaying cardiomyocytes senescence is of gr
Externí odkaz:
https://doaj.org/article/9da5fb221e7c4a66af4611039fd56328
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dda2fcd23f0d1226ed1f58b7b3774e91
https://doi.org/10.2139/ssrn.4374090
https://doi.org/10.2139/ssrn.4374090