Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Ruo-Lan Qian"'
Publikováno v:
Guoji Yanke Zazhi, Vol 19, Iss 10, Pp 1717-1721 (2019)
AIM: To evaluate the efficacy and safety of ripasudil in the treatment of glaucoma in recent years by Meta-analysis.METHODS:According to the Cochrane systematic review method, we searched three databases(Pubmed, Web of Knowledge and CNKI). The change
Externí odkaz:
https://doaj.org/article/224aaf829bb64034bd7f4a796e5cd639
Autor:
Ruo Lan Qian, Wen Jie Guo, Zi Yuan Zou, Si Han Liu, Xin Chen, Xiaoli Zhang, Ya Ting Chen, Peng Luo
Publikováno v:
Drug Design, Development and Therapy
Non-small-cell lung cancer (NSCLC) is a common disease threatening the health of humankind. It has a low survival rate and a poor prognosis. Under normal circumstances, tumor infiltrating lymphocytes (TILs) play the main role in the antitumor process
Autor:
Shubing Zhang, Lei Yang, Chunhui Hou, Wei Ying Zhou, Xiao Dong Cheng, Ruo Lan Qian, Heng Yue Xie, Xuejun Zhang
Publikováno v:
Acta Biochimica et Biophysica Sinica. 36:211-217
Huangqi (Astragalus membranaceus), a traditional Chinese medicine, has been used to ameliorate side effects of cancer chemotherapy in China. However, little is known about its molecular mechanisms. Here we show that induction of K562 or HEL cells wit
Autor:
Shubing Zhang, Ruo Lan Qian
Publikováno v:
Cell Research. 12:411-416
Our previous study showed that hydroxyurea (Hu) could induce HEL cells to express human beta-globin gene. However the molecular mechanisms by which the expression of beta-globin gene is activated and regulated are poorly understood. Here we show that
Publikováno v:
Cell Research. 12:79-82
The developmental control of the human epsilon-globin gene expression is mediated by transcription regulatory elements in the 5' flanking DNA of this gene. Sequence analysis has revealed a DNA motif (GGGGAATTTGCT) similar to NF-kappaB consensus seque
Publikováno v:
Cell Research. 11:301-310
HEL cells, a human erythroleukemia cell line, mainly express the fetal (gamma) globin gene and trace amount of the embryonic (epsilon) globin gene, but not adult (beta) globin gene. Here we show that hydroxyurea (HU) can induce HEL cells to express a
Publikováno v:
Cell Research. 9:255-260
The structure of the nucleosome core particle of chromatin in chicken erythrocytes has been examined by using AFM. The 146 bp of DNA wrapped twice around the core histone octamer are clearly visualized. Both the ends of entry/exit of linker DNA are a
Autor:
Ruo Lan Qian, Zhi Jiang Yan
Publikováno v:
Cell Research. 8:209-218
The nuclear matrix attachment regions(MARs) and the binding nuclear matrix proteins in the 5'-flanking cis-acting elements of the human epsilon-globin gene have been examined. Using in vitro DNA-matrix binding assay, it has been shown that the positi
Publikováno v:
Cell Research. 6:101-114
The erythroid- and developmental stage-specific expression of the human ɛ-globin gene is controlled, in part, by the 5′-flanking DNA sequence of this gene. In the present study, we have used DNA-protein binding assays to identify trans-acting fact
Publikováno v:
Cell research. 18(2)
GATA-1 is a hematopoietic transcription factor that is essential for the terminal maturation of proerythroblasts, megakaryocytic cells and mast cells. The erythroid-specific promoter of the human GATA-1 gene directs the high expression of a reporter