Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Ruo-Lan Li"'
Autor:
Ming-Qiao Li, Yu-Qi He, Meng-Ni Zhang, Wan Tang, Ya Tan, Yue Cheng, Mei Yang, Nan Zhao, Ling Li, Si-Rui Yu, Ruo-Lan Li, Qiong Pan, Ming-Yue Wu, Jin Chai
Publikováno v:
Cell Death and Disease, Vol 15, Iss 10, Pp 1-10 (2024)
Abstract Pancreatic cancer is one of the leading causes of cancer-associated mortality, with a poor treatment approach. Previous study has shown that inducing pyroptosis in pancreatic ductal adenocarcinoma (PDAC) slows the growth of PDACs, implying t
Externí odkaz:
https://doaj.org/article/0a8d54c33b8e4ab4a6bfe7fb974ff3bc
Publikováno v:
Arabian Journal of Chemistry, Vol 17, Iss 8, Pp 105843- (2024)
Background: The traditional Chinese medicine Ligusticum chuanxiong Hort. (CHX) has been used in the management of heart disease, particularly myocardial ischemia (MI), but its related active constituents and mechanisms remain to be further explored.
Externí odkaz:
https://doaj.org/article/e4bd9e2b0f784a8bb18cc7ccc3c7b818
Autor:
Juan Guo, Cheng-Xun He, Qing Zhang, Ruo-Lan Li, Die Qian, Chun-Jie Wu, Wen-Wen Chen, Shu-Guang Hou, Wei Peng
Publikováno v:
Arabian Journal of Chemistry, Vol 17, Iss 3, Pp 105594- (2024)
The pericarp of Zanthoxylum bungeanum Maxim. (ZBM) (Rutaceae), also called Sichuan pepper, is a famous condiment and herbal medicine existing in China dating back over 2000 years. In this paper, we summarized the active compounds and pharmacological
Externí odkaz:
https://doaj.org/article/65851da2cd6f42819acc29991927980e
Publikováno v:
Arabian Journal of Chemistry, Vol 17, Iss 1, Pp 105377- (2024)
Background: It’s known that respiratory diseases are the top of the list of systemic diseases, and accumulating evidence suggests that one of the important reasons for the high incidence of respiratory diseases is the difficulty in delivering drugs
Externí odkaz:
https://doaj.org/article/ef9dbbccb4c44d79ac421d7abc4d279f
Publikováno v:
Pharmacological Research, Vol 196, Iss , Pp 106923- (2023)
Under physiological or pathological conditions, transient receptor potential (TRP) channel vanilloid type 1 (TRPV1) and TRP ankyrin 1 (TRPA1) possess the ability to detect a vast array of stimuli and execute diverse functions. Interestingly, increasi
Externí odkaz:
https://doaj.org/article/3a6997f0abc64ba2b44113cb9c11c92e
Publikováno v:
Arabian Journal of Chemistry, Vol 16, Iss 7, Pp 104817- (2023)
Neurodegenerative diseases are neurological diseases that are characterized by neuronal degeneration and apoptosis; they threaten populations around the world and place a great burden on the social economy. Unfortunately, the drugs currently used to
Externí odkaz:
https://doaj.org/article/4d48ee04d0be444c9f5a3bb750c91292
Publikováno v:
Toxics, Vol 12, Iss 2, p 100 (2024)
Hydroxy-α-sanshool (HAS) is the predominant active compound in Zanthoxylum bungeanum Maxim (ZBM). Our present work was aimed to explore the in vitro metabolism characteristics, and in vivo pharmacokinetic (PK) profile of HAS. Plasma (human), liver m
Externí odkaz:
https://doaj.org/article/38a1b1a2071a43a2979f80cc3c9b8623
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
As the common pathological basis of various cardiovascular diseases, the morbidity and mortality of atherosclerosis (AS) have increased in recent years. Unfortunately, there are still many problems in the treatment of AS, and the prevention and treat
Externí odkaz:
https://doaj.org/article/3c990a9e30a8498386cce9553ffedd8f
Autor:
Qing Zhang, Ruo-Lan Li, Ling-Yu Wang, Ting Zhang, Die Qian, Dan-Dan Tang, Cheng-Xun He, Chun-Jie Wu, Li Ai
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Type 2 diabetes mellitus (T2DM) is a chronic metabolic disease characterized by hyperglycemia. The fruits of Zanthoxylum bungeanum Maxim. is a common spice and herbal medicine in China, and hydroxy-α-sanshool (HAS) is the most abundant amide in Z. b
Externí odkaz:
https://doaj.org/article/7d45fa2de5534d76af3262a53a336c21
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 26, Iss 9, Pp 572-589 (2021)
Introduction: The ambiguity of the drug target is one of the major factors restricting the development of traditional Chinese medicine (TCMs) and its bioactive constituents. The characteristics of “multiple components, multiple targets and multiple
Externí odkaz:
https://doaj.org/article/55a7bea74df44b28af1d3dfe3c880a4f